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01-01-2018 | Original Article

Results of transurethral resection of the prostate in renal transplant recipients: a single center experience

Authors: Mehmet Sarier, Sabri Tekin, İbrahim Duman, Yucel Yuksel, Meltem Demir, Furkan Alptekinkaya, Mehmet Guler, Asuman Havva Yavuz, Alim Kosar

Published in: World Journal of Urology | Issue 1/2018

Abstract

Objectives

The aim of this study was to retrospectively evaluate the early and long-term results of renal transplantation (RT) patients undergoing transurethral resection of the prostate (TURP) due to benign prostate hyperplasia (BPH).

Materials and methods

Eighty-nine patients with RT performed in our hospital underwent TURP between November 2008 and March 2016. Results were evaluated along with early and long-term complications. Patients were followed up for a minimum of 12 months.

Results

The mean age of the patients was 61.4 ± 7.4 years. The median duration of dialysis was 28 (0–180) months. The median duration between transplantation and TURP was 13 (0–84) months. Before TURP, the mean serum creatinine (sCr) was 1.99 ± 0.83 mg/dL and the mean prostate volume was 33.3 ± 14.6 cm³. The mean Q _max, Q _ave and PVR values were 9.5 ± 3.7, 5.2 ± 2.2 ml/s and 85(5–480) mL, respectively. None of the patients developed perioperative and postoperative major complications. Twelve patients (13.4%) developed urinary tract infections in the postoperative period. The sCr, IPSS and PVR values significantly decreased, while Q _max and Q _ave significantly increased at the 1-month follow-up. At the 6-month follow-up, 63 (70.8%) patients had retrograde ejaculation. Patients were followed up for a median of 42 (12–96) months. Three patients (3.3%) were re-operated for bladder neck contracture and eight (8.9%) patients were re-operated for urethral stricture.

Conclusion

TURP can be safely and successfully applied for the treatment of BPH after RT. LUTS and renal functions significantly improve after the operation. Patients should be followed up for UTIs in the short term and for urethral stricture in the long term.

Evans RW, Manninen DL, Garrison LP et al (1985) The quality of life of patients with end-stage renal disease. N Engl J Med 312(9):553–559CrossRefPubMed

Szlauer R, Götschl R, Razmaria A, Paras L, Schmeller NT (2009) Endoscopic vaporesection of the prostate using the continuous-wave 2-microm thulium laser: outcome and demonstration of the surgical technique. Eur Urol 55(2):368–375CrossRefPubMed

Rule A, Lieber M, Jacobsen S (2005) Is benign prostatic hyperplasia a risk factor for chronic renal failure? J Urol 173(3):691–696CrossRefPubMed

Lourenco T, Shaw M, Fraser C, MacLennan G, N’Dow J, Pickard R (2010) The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials. World J Urol 28(1):23–32CrossRefPubMed

Rassweiler J, Teber D, Kuntz R, Hofmann R (2006) Complications of transurethral resection of the prostate (TURP)—incidence, management, and prevention. Eur Urol 50(5):969–980CrossRefPubMed

Reinberg Y, Manivel JC, Sidi AA, Ercole CJ (1992) Transurethral resection of prostate immediately after renal transplantation. Urology 39(4):319–321CrossRefPubMed

Fitzpatrick JM (2006) The natural history of benign prostatic hyperplasia. BJU Int. 97(SUPPL. 2):3–6CrossRefPubMed

Power RE, Hickey DP, Little DM (2004) Urological evaluation prior to renal transplantation. Transplant Proc 36(10):2962–2967CrossRefPubMed

Hurst FP, Neff RT, Falta EM et al (2009) Incidence, predictors, and associated outcomes of prostatism after kidney transplantation. Clin J Am Soc Nephrol 4(2):329–336CrossRefPubMedPubMedCentral

10.

Ghose RR (1990) Prolonged recovery of renal function after prostatectomy for prostatic outflow obstruction. BMJ 300(6736):1376–1377CrossRefPubMedPubMedCentral

11.

Volpe A, Billia M, Quaglia M et al (2013) Transurethral resection of the prostate in kidney transplant recipients: urological and renal functional outcomes at long-term follow-up. BJU Int 112(3):386–393CrossRefPubMed

12.

Kabler RL, Cerny JC (1983) Pre-transplant urologic investigation and treatment of end stage renal disease. J Urol 129(3):475–478CrossRefPubMed

13.

Shenasky JH (1976) Renal transplantation in patients with urologic abnormalities. J Urol 115(5):490–493CrossRefPubMed

14.

Védrine N, Nsabimbona B, Soares P, Deteix P, Boiteux J-P, Guy L (2009) Résection transuréthrale de prostate ou incision cervicoprostatique dans les suites immédiates d’une transplantation rénale. Progrès en Urol 19(11):845–849CrossRef

15.

Mokos I, Kastelan Z, Basić-Jukić N, Kes P, Pasini J (2011) Transurethral incision/resection of the prostate (TUIP/TURP) in operative treatment of repeated bladder outlet obstruction early after kidney transplantation. Acta Clin Croat 50(3):381–384PubMed

16.

Ahyai SA, Gilling P, Kaplan SA et al (2010) Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 58(3):384–397CrossRefPubMed

17.

Karuthu S, Blumberg EA (2012) Common infections in kidney transplant recipients. Clin J Am Soc Nephrol 7(12):2058–2070CrossRefPubMed

18.

Pellé G, Vimont S, Levy PP et al (2007) Acute pyelonephritis represents a risk factor impairing long-term kidney graft function. Am J Transplant 7(4):899–907CrossRefPubMed

19.

Shoskes D, Hanbury D, Cranston D, Morris P (1995) Urological complications in 1,000 consecutive renal transplant recipients. J Urol 153:18–21CrossRefPubMed

20.

Streeter EH, Little DM, Cranston DW, Morris PJ (2002) The urological complications of renal transplantation: a series of 1535 patients. BJU Int 90(7):627–634CrossRefPubMed

21.

Grabe M, Bartoletti R, Bjerklund-Johansen TE et al (2015) Guidelines on urological infections. Eur Assoc Urol 1:50–58

22.

Taylor BL, Jaffe WI (2015) Electrosurgical transurethral resection of the prostate and transurethral incision of the prostate (monopolar techniques). Can J Urol 22(Suppl 1):24–29PubMed

23.

Nielsen KK, Nordling J (1990) Urethral stricture following transurethral prostatectomy. Urology 35(1):18–24CrossRefPubMed

24.

Fenton AS, Morey AF, Aviles R, Garcia CR (2005) Anterior urethral strictures: etiology and characteristics. Urology 65(6):1055–1058CrossRefPubMed

25.

Edwards LE, Bucknall TE, Pittam MR, Richardson DR, Stanek J (1985) Transurethral resection of the prostate and bladder neck incision: a review of 700 cases. Br J Urol 57(2):168–171CrossRefPubMed

26.

Madersbacher S, Alivizatos G, Nordling J, Sanz CR, Emberton M, de la Rosette JJMCH (2004) EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). Eur Urol 46(5):547–554CrossRefPubMed

27.

Pertuz W, Castaneda DA, Rincon O, Lozano E (2014) Sexual dysfunction in patients with chronic renal disease: does it improve with renal transplantation? Transplant Proc 46:3021–3026CrossRefPubMed

28.

Yadav R, Mehta SN, Kumar A, Guleria S, Seenu V, Tiwari SC (2008) A prospective analysis of testicular androgenic function in recipients of a renal allograft. Int Urol Nephrol 40(2):397–403CrossRefPubMed

29.

Reich O, Gratzke C, Stief CG (2006) Techniques and long-term results of surgical procedures for BPH. Eur Urol 49(6):970–978CrossRefPubMed

Title: Results of transurethral resection of the prostate in renal transplant recipients: a single center experience
Authors: Mehmet Sarier
Sabri Tekin
İbrahim Duman
Yucel Yuksel
Meltem Demir
Furkan Alptekinkaya
Mehmet Guler
Asuman Havva Yavuz
Alim Kosar
Publication date: 01-01-2018
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 1/2018
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-017-2094-5

At a glance: The STEP trials

Springer Medicine

Results of transurethral resection of the prostate in renal transplant recipients: a single center experience

Abstract

Objectives

Materials and methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusion

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