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Open Access 01-05-2017 | Original Article

Utilization of multiparametric prostate magnetic resonance imaging in clinical practice and focal therapy: report from a Delphi consensus project

Authors: M. J. Scheltema, K. J. Tay, A. W. Postema, D. M. de Bruin, J. Feller, J. J. Futterer, A. K. George, R. T. Gupta, F. Kahmann, C. Kastner, M. P. Laguna, S. Natarajan, S. Rais-Bahrami, A. R. Rastinehad, T. M. de Reijke, G. Salomon, N. Stone, R. van Velthoven, R. Villani, A. Villers, J. Walz, T. J. Polascik, J. J. M. C. H. de la Rosette

Published in: World Journal of Urology | Issue 5/2017

Abstract

Purpose

To codify the use of multiparametric magnetic resonance imaging (mpMRI) for the interrogation of prostate neoplasia (PCa) in clinical practice and focal therapy (FT).

Methods

An international collaborative consensus project was undertaken using the Delphi method among experts in the field of PCa. An online questionnaire was presented in three consecutive rounds and modified each round based on the comments provided by the experts. Subsequently, a face-to-face meeting was held to discuss and finalize the consensus results.

Results

mpMRI should be performed in patients with prior negative biopsies if clinical suspicion remains, but not instead of the PSA test, nor as a stand-alone diagnostic tool or mpMRI-targeted biopsies only. It is not recommended to use a 1.5 Tesla MRI scanner without an endorectal or pelvic phased-array coil. mpMRI should be performed following standard biopsy-based PCa diagnosis in both the planning and follow-up of FT. If a lesion is seen, MRI-TRUS fusion biopsies should be performed for FT planning. Systematic biopsies are still required for FT planning in biopsy-naïve patients and for patients with residual PCa after FT. Standard repeat biopsies should be taken during the follow-up of FT. The final decision to perform FT should be based on histopathology. However, these consensus statements may differ for expert centers versus non-expert centers.

Conclusions

The mpMRI is an important tool for characterizing and targeting PCa in clinical practice and FT. Standardization of acquisition and reading should be the main priority to guarantee consistent mpMRI quality throughout the urological community.

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Title: Utilization of multiparametric prostate magnetic resonance imaging in clinical practice and focal therapy: report from a Delphi consensus project
Authors: M. J. Scheltema
K. J. Tay
A. W. Postema
D. M. de Bruin
J. Feller
J. J. Futterer
A. K. George
R. T. Gupta
F. Kahmann
C. Kastner
M. P. Laguna
S. Natarajan
S. Rais-Bahrami
A. R. Rastinehad
T. M. de Reijke
G. Salomon
N. Stone
R. van Velthoven
R. Villani
A. Villers
J. Walz
T. J. Polascik
J. J. M. C. H. de la Rosette
Publication date: 01-05-2017
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 5/2017
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-016-1932-1

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Utilization of multiparametric prostate magnetic resonance imaging in clinical practice and focal therapy: report from a Delphi consensus project

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

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Abstract

Purpose

Methods

Results

Conclusions

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