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Published in: European Radiology 8/2020

Open Access 01-08-2020 | Mammography | Breast

Digital zoom of the full-field digital mammogram versus magnification mammography: a systematic review

Authors: Mona Øynes, Bergliot Strøm, Bente Tveito, Bjørg Hafslund

Published in: European Radiology | Issue 8/2020

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Abstract

Objectives

To summarise and compare the performance of magnification mammography and digital zoom utilising a full-field digital mammography (FFDM) system in the detection and diagnosis of microcalcifications.

Methods

We ran an extended search in MEDLINE, EMBASE, CINAHL, Engineering Village and Web of Science. Diagnostic test studies, experimental breast phantom studies and a Monte Carlo phantom study were included. A narrative approach was selected to summarise and compare findings regarding the detection of microcalcifications, while a hierarchical model with bivariate analysis was used for the meta-analysis of sensitivity and specificity for diagnosing microcalcifications.

Results

Nine studies were included. Phantom studies suggested that the size of microcalcifications, magnification or zoom factor, exposure factors and detector technology determine whether digital zoom is equivalent to magnification mammography in the detection of microcalcifications. Pooled sensitivity for magnification and zoom calculated from the diagnostic test studies was 0.93 (95% CI 0.84–0.97) and 0.85 (95% CI 0.70–0.94), respectively. Pooled specificity was 0.55 (95% CI 0.51–0.58) and 0.56 (95% CI 0.50–0.62), respectively. The differences between the sensitivities and specificities were not statistically significant.

Conclusions

Digital zoom may be equivalent to magnification mammography. Diagnostic test studies and phantom studies using newer detector technology would contribute additional knowledge on this topic.

Key Points

• The performance of digital zoom is comparable to magnification for detecting microcalcifications when newer detector technology and optimised imaging procedures are utilised.
• The accuracy of digital zoom appears equivalent to geometric magnification in diagnosing microcalcifications.
Appendix
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Literature
1.
go back to reference Itani M, Griffin AT, Whitman GJ (2013) Mammography of breast calcifications. Imaging Med 5:63–74CrossRef Itani M, Griffin AT, Whitman GJ (2013) Mammography of breast calcifications. Imaging Med 5:63–74CrossRef
2.
go back to reference Muttarak M, Kongmebhol P, Sukhamwang N (2009) Breast calcifications: which are malignant. Singapore Med J 50:907–914PubMed Muttarak M, Kongmebhol P, Sukhamwang N (2009) Breast calcifications: which are malignant. Singapore Med J 50:907–914PubMed
3.
go back to reference Perry N, Broeders M, de Wolf C, Törnberg S, Holland R, von Karsa L (eds) (2006) European guidelines for quality assurance in breast cancer screening and diagnosis, fourth edition. Health & Consumer Protection Directorate-General, European Communities, Luxembourg Perry N, Broeders M, de Wolf C, Törnberg S, Holland R, von Karsa L (eds) (2006) European guidelines for quality assurance in breast cancer screening and diagnosis, fourth edition. Health & Consumer Protection Directorate-General, European Communities, Luxembourg
4.
go back to reference Bick U, Diekmann F (2007) Digital mammography: what do we and what don’t we know? Eur Radiol 17:1931–1942CrossRef Bick U, Diekmann F (2007) Digital mammography: what do we and what don’t we know? Eur Radiol 17:1931–1942CrossRef
5.
go back to reference Geller BM, Vacek PM, Skelly J, Harvey SC (2005) The use of additional imaging increased specificity and decreased sensitivity in screening mammography. J Clin Epidemiol 58:942–950CrossRef Geller BM, Vacek PM, Skelly J, Harvey SC (2005) The use of additional imaging increased specificity and decreased sensitivity in screening mammography. J Clin Epidemiol 58:942–950CrossRef
6.
go back to reference Madan AK, Nguyen MT, Wakabayashi MN, Beech DJ (2001) Magnification views of mammography decrease biopsy rates. Am Surg 67:687–689PubMed Madan AK, Nguyen MT, Wakabayashi MN, Beech DJ (2001) Magnification views of mammography decrease biopsy rates. Am Surg 67:687–689PubMed
7.
go back to reference Bosmans H, Carton A-K, Rogge F et al (2005) Image quality measurements and metrics in full field digital mammography: an overview. Radiat Prot Dosimetry 117:120–130CrossRef Bosmans H, Carton A-K, Rogge F et al (2005) Image quality measurements and metrics in full field digital mammography: an overview. Radiat Prot Dosimetry 117:120–130CrossRef
8.
go back to reference Suryanarayanan S, Karellas A, Vedantham S, Sechopoulos I, D’Orsi CJ (2007) Detection of simulated microcalcifications in a phantom with digital mammography: effect of pixel size. Radiology 244:130–137CrossRef Suryanarayanan S, Karellas A, Vedantham S, Sechopoulos I, D’Orsi CJ (2007) Detection of simulated microcalcifications in a phantom with digital mammography: effect of pixel size. Radiology 244:130–137CrossRef
9.
go back to reference Ruschin M, Hemdal B, Andersson I et al (2005) Threshold pixel size for shape determination of microcalcifications in digital mammography: a pilot study. Radiat Prot Dosimetry 114:415–423CrossRef Ruschin M, Hemdal B, Andersson I et al (2005) Threshold pixel size for shape determination of microcalcifications in digital mammography: a pilot study. Radiat Prot Dosimetry 114:415–423CrossRef
10.
go back to reference Noel A, Thibault F (2004) Digital detectors for mammography: the technical challenges. Eur Radiol 14:1990–1998CrossRef Noel A, Thibault F (2004) Digital detectors for mammography: the technical challenges. Eur Radiol 14:1990–1998CrossRef
11.
go back to reference Saunders RS, Baker JA, Delong DM, Johnson JP, Samei E (2007) Does image quality matter? Impact of resolution and noise on mammographic task performance. Med Phys 34:3971–3981CrossRef Saunders RS, Baker JA, Delong DM, Johnson JP, Samei E (2007) Does image quality matter? Impact of resolution and noise on mammographic task performance. Med Phys 34:3971–3981CrossRef
12.
go back to reference Tanaka N, Naka K, Kumazawa S et al (2009) Imaging properties of digital magnification mammography. World Congress on Medical Physics and Biomedical Engineering, Munich, Germany. Springer, pp 64–66 Tanaka N, Naka K, Kumazawa S et al (2009) Imaging properties of digital magnification mammography. World Congress on Medical Physics and Biomedical Engineering, Munich, Germany. Springer, pp 64–66
13.
go back to reference Zanca F, Jacobs J, Van Ongeval C et al (2009) Evaluation of clinical image processing algorithms used in digital mammography. Med Phys 36:765–775CrossRef Zanca F, Jacobs J, Van Ongeval C et al (2009) Evaluation of clinical image processing algorithms used in digital mammography. Med Phys 36:765–775CrossRef
14.
go back to reference Krupinski EA, Roehrig H, Dallas W, Fan J (2005) Differential use of image enhancement techniques by experienced and inexperienced observers. J Digit Imaging 18:311–315CrossRef Krupinski EA, Roehrig H, Dallas W, Fan J (2005) Differential use of image enhancement techniques by experienced and inexperienced observers. J Digit Imaging 18:311–315CrossRef
15.
go back to reference Park H-S, Oh Y, Kim S-T, Kim H-J (2012) Effects of breast thickness and lesion location on resolution in digital magnification mammography. Clin Imaging 36:255–262CrossRef Park H-S, Oh Y, Kim S-T, Kim H-J (2012) Effects of breast thickness and lesion location on resolution in digital magnification mammography. Clin Imaging 36:255–262CrossRef
16.
go back to reference Koutalonis M, Delis H, Spyrou G, Costaridou L, Tzanakos G, Panayiotakis G (2008) Monte Carlo studies on the influence of focal spot size and intensity distribution on spatial resolution in magnification mammography. Phys Med Biol 53:1369–1674CrossRef Koutalonis M, Delis H, Spyrou G, Costaridou L, Tzanakos G, Panayiotakis G (2008) Monte Carlo studies on the influence of focal spot size and intensity distribution on spatial resolution in magnification mammography. Phys Med Biol 53:1369–1674CrossRef
17.
go back to reference Liu B, Goodsitt M, Chan H-P (1995) Normalized average glandular dose in magnification mammography. Radiology 197:27–32CrossRef Liu B, Goodsitt M, Chan H-P (1995) Normalized average glandular dose in magnification mammography. Radiology 197:27–32CrossRef
18.
go back to reference Law J (2005) Breast dose from magnification films in mammography. Br J Radiol 78:816–820CrossRef Law J (2005) Breast dose from magnification films in mammography. Br J Radiol 78:816–820CrossRef
19.
go back to reference Perisinakis K, Damilakis J, Kontogiannis E, Gourtsoyiannis N (2001) Film-screen magnification versus electronic magnification and enhancement of digitized contact mammograms in the assessment of subtle microcalcifications. Invest Radiol 36:726–733CrossRef Perisinakis K, Damilakis J, Kontogiannis E, Gourtsoyiannis N (2001) Film-screen magnification versus electronic magnification and enhancement of digitized contact mammograms in the assessment of subtle microcalcifications. Invest Radiol 36:726–733CrossRef
20.
go back to reference Fischer U, Baum F, Obenauer S, Funke M, Hermann K, Grabbe E (2002) Digital full field mammography: comparison between radiographic direct magnification and digital monitor zooming. Radiologe 42:261–264CrossRef Fischer U, Baum F, Obenauer S, Funke M, Hermann K, Grabbe E (2002) Digital full field mammography: comparison between radiographic direct magnification and digital monitor zooming. Radiologe 42:261–264CrossRef
21.
go back to reference Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264–269CrossRef Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264–269CrossRef
24.
go back to reference Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A (2016) Rayyan—a web and mobile app for systematic reviews. Syst Rev 5:210–219CrossRef Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A (2016) Rayyan—a web and mobile app for systematic reviews. Syst Rev 5:210–219CrossRef
25.
go back to reference Whiting PF, Rutjes AW, Westwood ME et al (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRef Whiting PF, Rutjes AW, Westwood ME et al (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRef
26.
go back to reference Macaskill P, Gatsonis C, Deeks JJ, Harbord RM, Takwoingi Y (2010) Analysing and presenting results. In: Deeks JJ, Bossuyt P, Gatsonis C (eds) Cochrane handbook for systematic reviews of diagnostic test accuracy version 10. The Cochrane Collaboration Macaskill P, Gatsonis C, Deeks JJ, Harbord RM, Takwoingi Y (2010) Analysing and presenting results. In: Deeks JJ, Bossuyt P, Gatsonis C (eds) Cochrane handbook for systematic reviews of diagnostic test accuracy version 10. The Cochrane Collaboration
27.
go back to reference Chu H, Cole SR (2006) Bivariate meta-analysis of sensitivity and specificity with sparse data: a generalized linear mixed model approach. J Clin Epidemiol 59:1331CrossRef Chu H, Cole SR (2006) Bivariate meta-analysis of sensitivity and specificity with sparse data: a generalized linear mixed model approach. J Clin Epidemiol 59:1331CrossRef
28.
go back to reference Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH (2005) Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol 58:982–990CrossRef Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH (2005) Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol 58:982–990CrossRef
29.
go back to reference Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558CrossRef Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558CrossRef
30.
go back to reference Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560CrossRef Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560CrossRef
32.
go back to reference Sterne JAC, Egger, M, Moher, D (2011) Addressing reporting biases. In: Higgins J, Green, S, (ed) Cochrane Handbook for Systematic Reviews of Interventions, The Cochrane Collaboration Sterne JAC, Egger, M, Moher, D (2011) Addressing reporting biases. In: Higgins J, Green, S, (ed) Cochrane Handbook for Systematic Reviews of Interventions, The Cochrane Collaboration
34.
36.
go back to reference Alkhalifah K, Brindhaban A, Asbeutah A (2016) Comparison between image quality in electronic zoom and geometric magnification in digital mammography. J Xray Sci Technol 24:681–689PubMed Alkhalifah K, Brindhaban A, Asbeutah A (2016) Comparison between image quality in electronic zoom and geometric magnification in digital mammography. J Xray Sci Technol 24:681–689PubMed
37.
go back to reference Egan G, Keavey E, Phelan N (2012) Comparison of contact spot imaging on a scanning mammography system to conventional geometric magnification imaging. International Workshop on Digital Mammography. Springer, pp 165–172 Egan G, Keavey E, Phelan N (2012) Comparison of contact spot imaging on a scanning mammography system to conventional geometric magnification imaging. International Workshop on Digital Mammography. Springer, pp 165–172
38.
go back to reference Vahey K, Ryan E, McLean D, Poulos A, Rickard M (2012) A comparison between the electronic magnification (EM) and true magnification (TM) of breast phantom images using a CDMAM phantom. Eur J Radiol 81:1514–1519CrossRef Vahey K, Ryan E, McLean D, Poulos A, Rickard M (2012) A comparison between the electronic magnification (EM) and true magnification (TM) of breast phantom images using a CDMAM phantom. Eur J Radiol 81:1514–1519CrossRef
39.
go back to reference Koutalonis M, Delis H, Pascoal A, Spyrou G, Costaridou L, Panayiotakis G (2010) Can electronic zoom replace magnification in mammography? A comparative Monte Carlo study. Br J Radiol 83:569–577CrossRef Koutalonis M, Delis H, Pascoal A, Spyrou G, Costaridou L, Panayiotakis G (2010) Can electronic zoom replace magnification in mammography? A comparative Monte Carlo study. Br J Radiol 83:569–577CrossRef
40.
go back to reference Hermann K-P, Obenauer S, Funke M, Grabbe E (2002) Magnification mammography: a comparison of full-field digital mammography and screen-film mammography for the detection of simulated small masses and microcalcifications. Eur Radiol 12:2188–2191CrossRef Hermann K-P, Obenauer S, Funke M, Grabbe E (2002) Magnification mammography: a comparison of full-field digital mammography and screen-film mammography for the detection of simulated small masses and microcalcifications. Eur Radiol 12:2188–2191CrossRef
41.
go back to reference Fallenberg E, Dimitrijevic L, Diekmann F et al (2014) Impact of magnification views on the characterization of microcalcifications in digital mammography. Rofo 186:274–280 Fallenberg E, Dimitrijevic L, Diekmann F et al (2014) Impact of magnification views on the characterization of microcalcifications in digital mammography. Rofo 186:274–280
42.
go back to reference Moraux-Wallyn M, Chaveron C, Bachelle F, Taieb S, Ceugnart L (2010) Comparison between electronic zoom and geometric magnification of clusters of microcalcifications on digital mammography. J Radiol 91:879–883CrossRef Moraux-Wallyn M, Chaveron C, Bachelle F, Taieb S, Ceugnart L (2010) Comparison between electronic zoom and geometric magnification of clusters of microcalcifications on digital mammography. J Radiol 91:879–883CrossRef
43.
go back to reference Kim M, Youk J, Kang D et al (2010) Zooming method (× 2.0) of digital mammography vs digital magnification view (× 1.8) in full-field digital mammography for the diagnosis of microcalcifications. Br J Radiol 83:486–492CrossRef Kim M, Youk J, Kang D et al (2010) Zooming method (× 2.0) of digital mammography vs digital magnification view (× 1.8) in full-field digital mammography for the diagnosis of microcalcifications. Br J Radiol 83:486–492CrossRef
44.
go back to reference Kim MJ, Kim EK, Kwak JY et al (2009) Characterization of microcalcification: can digital monitor zooming replace magnification mammography in full-field digital mammography? Eur Radiol 19:310–317CrossRef Kim MJ, Kim EK, Kwak JY et al (2009) Characterization of microcalcification: can digital monitor zooming replace magnification mammography in full-field digital mammography? Eur Radiol 19:310–317CrossRef
47.
go back to reference Spyrou G, Panayuotakis G, Tzanakos G (2000) MASTOS: mammography simulation tool for design optimization studies. Med Inform Internet Med 25:275–293CrossRef Spyrou G, Panayuotakis G, Tzanakos G (2000) MASTOS: mammography simulation tool for design optimization studies. Med Inform Internet Med 25:275–293CrossRef
48.
go back to reference Balleyguier C, Ayadi S, Van Nguyen K, Vanel D, Dromain C, Sigal R (2007) BIRADS™ classification in mammography. Eur J Radiol 61:192–194CrossRef Balleyguier C, Ayadi S, Van Nguyen K, Vanel D, Dromain C, Sigal R (2007) BIRADS™ classification in mammography. Eur J Radiol 61:192–194CrossRef
49.
go back to reference Cederström B, Fredenberg E (2014) The influence of anatomical noise on optimal beam quality in mammography. Med Phys 41:121903CrossRef Cederström B, Fredenberg E (2014) The influence of anatomical noise on optimal beam quality in mammography. Med Phys 41:121903CrossRef
Metadata
Title
Digital zoom of the full-field digital mammogram versus magnification mammography: a systematic review
Authors
Mona Øynes
Bergliot Strøm
Bente Tveito
Bjørg Hafslund
Publication date
01-08-2020
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 8/2020
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-020-06798-6

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