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01-01-2020 | Cardiac

Compressed sensing real-time cine imaging for assessment of ventricular function, volumes and mass in clinical practice

Authors: Mathilde Vermersch, Benjamin Longère, Augustin Coisne, Michaela Schmidt, Christoph Forman, Aurélien Monnet, Julien Pagniez, Valentina Silvestri, Arianna Simeone, Emma Cheasty, David Montaigne, François Pontana

Published in: European Radiology | Issue 1/2020

Abstract

Objectives

This study was conducted in order to evaluate the accuracy of a compressed sensing (CS) real-time single-breath-hold cine sequence for the assessment of left and right ventricular functional parameters in daily practice.

Methods

Cardiac magnetic resonance (CMR) cine images were acquired from 100 consecutive patients using both the reference segmented multi-breath-hold steady-state free precession (SSFP) acquisition and a prototype single-breath-hold real-time CS sequence, providing the same slice number, position, and thickness. For both sequences, the left (LV) and right ventricular (RV) ejection fractions (EF) and end-diastolic volumes (EDV) were assessed as well as LV mass (LVM). The visualization of wall-motion disorders (WMD) and signal void related to mitral or tricuspid regurgitation was also analyzed.

Results

The CS sequence mean scan time was 23 ± 6 versus 510 ± 109 s for the multi-breath-hold SSFP sequence (p < 0.001). There was an excellent correlation between the two sequences regarding mean LVEF (r = 0.995), LVEDV (r = 0.997), LVM (r = 0.981), RVEF (r = 0.979), and RVEDV (r = 0.983). Moreover, inter- and intraobserver agreements were very strong with intraclass correlations of 0.96 and 0.99, respectively. On CS images, mitral or tricuspid regurgitation visualization was good (AUC = 0.85 and 0.81, respectively; ROC curve analysis) and wall-motion disorder visualization was excellent (AUC ≥ 0.97).

Conclusion

CS real-time single-breath-hold cine imaging reduces CMR scan duration by almost 20 times in daily practice while providing reliable measurements of both left and right ventricles. There was no clinically relevant information loss regarding valve regurgitation and wall-motion disorder depiction.

Key Points

• Compressed sensing single-breath-hold real-time cine imaging is a reliable sequence in daily practice.

• Fast CS real-time imaging reduces CMR scan time and improves patient workflow.

• There is no clinically relevant information loss with CS regarding heart valve regurgitation or wall-motion disorders.

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Title: Compressed sensing real-time cine imaging for assessment of ventricular function, volumes and mass in clinical practice
Authors: Mathilde Vermersch
Benjamin Longère
Augustin Coisne
Michaela Schmidt
Christoph Forman
Aurélien Monnet
Julien Pagniez
Valentina Silvestri
Arianna Simeone
Emma Cheasty
David Montaigne
François Pontana
Publication date: 01-01-2020
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 1/2020
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-019-06341-2

At a glance: The STEP trials

Springer Medicine

Compressed sensing real-time cine imaging for assessment of ventricular function, volumes and mass in clinical practice

Abstract

Objectives

Methods

Results

Conclusion

Key Points

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

Key Points

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