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European Radiology
Published in: European Radiology 12/2016

01-12-2016 | Cardiac

Real-time SPARSE-SENSE cardiac cine MR imaging: optimization of image reconstruction and sequence validation

Authors: Juliane Goebel, Felix Nensa, Bettina Bomas, Haemi P. Schemuth, Stefan Maderwald, Marcel Gratz, Harald H. Quick, Thomas Schlosser, Kai Nassenstein

Published in: European Radiology | Issue 12/2016

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Abstract

Objectives

Improved real-time cardiac magnetic resonance (CMR) sequences have currently been introduced, but so far only limited practical experience exists. This study aimed at image reconstruction optimization and clinical validation of a new highly accelerated real-time cine SPARSE-SENSE sequence.

Methods

Left ventricular (LV) short-axis stacks of a real-time free-breathing SPARSE-SENSE sequence with high spatiotemporal resolution and of a standard segmented cine SSFP sequence were acquired at 1.5 T in 11 volunteers and 15 patients. To determine the optimal iterations, all volunteers’ SPARSE-SENSE images were reconstructed using 10-200 iterations, and contrast ratios, image entropies, and reconstruction times were assessed. Subsequently, the patients’ SPARSE-SENSE images were reconstructed with the clinically optimal iterations. LV volumetric values were evaluated and compared between both sequences.

Results

Sufficient image quality and acceptable reconstruction times were achieved when using 80 iterations. Bland-Altman plots and Passing-Bablok regression showed good agreement for all volumetric parameters.

Conclusions

80 iterations are recommended for iterative SPARSE-SENSE image reconstruction in clinical routine. Real-time cine SPARSE-SENSE yielded comparable volumetric results as the current standard SSFP sequence. Due to its intrinsic low image acquisition times, real-time cine SPARSE-SENSE imaging with iterative image reconstruction seems to be an attractive alternative for LV function analysis.

Key Points

• A highly accelerated real-time CMR sequence using SPARSE-SENSE was evaluated.
• SPARSE-SENSE allows free breathing in real-time cardiac cine imaging.
• For clinically optimal SPARSE-SENSE image reconstruction, 80 iterations are recommended.
• Real-time SPARSE-SENSE imaging yielded comparable volumetric results as the reference SSFP sequence.
• The fast SPARSE-SENSE sequence is an attractive alternative to standard SSFP sequences.
Appendix
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Metadata
Title
Real-time SPARSE-SENSE cardiac cine MR imaging: optimization of image reconstruction and sequence validation
Authors
Juliane Goebel
Felix Nensa
Bettina Bomas
Haemi P. Schemuth
Stefan Maderwald
Marcel Gratz
Harald H. Quick
Thomas Schlosser
Kai Nassenstein
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 12/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4301-y

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