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European Radiology
Published in: European Radiology 3/2017

01-03-2017 | Breast

Technical feasibility proof for high-resolution low-dose photon-counting CT of the breast

Authors: Willi A. Kalender, Daniel Kolditz, Christian Steiding, Veikko Ruth, Ferdinand Lück, Ann-Christin Rößler, Evelyn Wenkel

Published in: European Radiology | Issue 3/2017

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Abstract

X-ray computed tomography (CT) has been proposed and evaluated multiple times as a potentially alternative method for breast imaging. All efforts shown so far have been criticized and partly disapproved because of their limited spatial resolution and higher patient dose when compared to mammography. Our concept for a dedicated breast CT (BCT) scanner therefore aimed at novel apparatus and detector design to provide high spatial resolution of about 100 μm and average glandular dose (AGD) levels of 5 mGy or below. Photon-counting technology was considered as a solution to reach these goals. The complete concept was previously evaluated and confirmed by simulations and basic experiments on laboratory setups. We here present measurements of dose, technical image quality parameters and surgical specimen results on such a scanner. For comparison purposes, the specimens were also imaged with digital mammography (DM) and breast tomosynthesis (BT) apparatus. Results show that photon-counting BCT (pcBCT) at 5 mGy AGD offers sufficiently high 3D spatial resolution for reliable detectability of calcifications and soft tissue delineation.

Key points

• Photon-counting detector technology allows for spatial resolution better than 100 μm.
• pcBCT allows for dose levels in the screening mammography range.
• pcBCT provides the highest quality imaging of microcalcifications.
Literature
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Metadata
Title
Technical feasibility proof for high-resolution low-dose photon-counting CT of the breast
Authors
Willi A. Kalender
Daniel Kolditz
Christian Steiding
Veikko Ruth
Ferdinand Lück
Ann-Christin Rößler
Evelyn Wenkel
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 3/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4459-3

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