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Published in: European Radiology 3/2017

Open Access 01-03-2017 | Gastrointestinal

Patient experience of CT colonography and colonoscopy after fecal occult blood test in a national screening programme

Authors: Andrew A. Plumb, Alex Ghanouni, Colin J. Rees, Paul Hewitson, Claire Nickerson, Suzanne Wright, Stuart A. Taylor, Steve Halligan, Christian von Wagner

Published in: European Radiology | Issue 3/2017

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Abstract

Objective

To investigate patient experience of CT colonography (CTC) and colonoscopy in a national screening programme.

Methods

Retrospective analysis of patient experience postal questionnaires. We included screenees from a fecal occult blood test (FOBt) based screening programme, where CTC was performed when colonoscopy was incomplete or deemed unsuitable. We analyzed questionnaire responses concerning communication of test risks, test-related discomfort and post-test pain, as well as complications. CTC and colonoscopy responses were compared using multilevel logistic regression.

Results

Of 67,114 subjects identified, 52,805 (79 %) responded. Understanding of test risks was lower for CTC (1712/1970 = 86.9 %) than colonoscopy (48783/50975 = 95.7 %, p < 0.0001). Overall, a slightly greater proportion of screenees found CTC unexpectedly uncomfortable (506/1970 = 25.7 %) than colonoscopy (10,705/50,975 = 21.0 %, p < 0.0001). CTC was tolerated well as a completion procedure for failed colonoscopy (unexpected discomfort; CTC = 26.3 %: colonoscopy = 57.0 %, p < 0.001). Post-procedural pain was equally common (CTC: 288/1970,14.6 %, colonoscopy: 7544/50,975,14.8 %; p = 0.55). Adverse event rates were similar in both groups (CTC: 20/2947 = 1.2 %; colonoscopy: 683/64,312 = 1.1 %), but generally less serious with CTC.

Conclusions

Even though CTC was reserved for individuals either unsuitable for or unable to complete colonoscopy, we found only small differences in test-related discomfort. CTC was well tolerated as a completion procedure and was extremely safe. CTC can be delivered across a national screening programme with high patient satisfaction.

Key Points

High patient satisfaction at CTC is deliverable across a national screening programme.
Patients who cannot tolerate screening colonoscopy are likely to find CTC acceptable.
CTC is extremely safe; complications are rare and almost never serious.
Patients may require more detailed information regarding the expected discomfort of CTC.
Literature
1.
go back to reference Robert G, Cornwell J, Brearley S, et al (2011) What matters to patients? Developing the evidence base for measuring and improving patient experience. Department of Health and NHS Institute for Innovation and Improvement Robert G, Cornwell J, Brearley S, et al (2011) What matters to patients? Developing the evidence base for measuring and improving patient experience. Department of Health and NHS Institute for Innovation and Improvement
2.
go back to reference Francis R (2013) Report of the Mid Staffordshire NHS Foundation Trust Public Inquiry Francis R (2013) Report of the Mid Staffordshire NHS Foundation Trust Public Inquiry
3.
go back to reference Benson VS, Atkin WS, Green J et al (2012) Toward standardizing and reporting colorectal cancer screening indicators on an international level: The International Colorectal Cancer Screening Network. Int J Cancer 130:2961–2973CrossRefPubMed Benson VS, Atkin WS, Green J et al (2012) Toward standardizing and reporting colorectal cancer screening indicators on an international level: The International Colorectal Cancer Screening Network. Int J Cancer 130:2961–2973CrossRefPubMed
4.
go back to reference Benson VS, Patnick J, Davies AK et al (2008) Colorectal cancer screening: a comparison of 35 initiatives in 17 countries. Int J Cancer 122:1357–1367CrossRefPubMed Benson VS, Patnick J, Davies AK et al (2008) Colorectal cancer screening: a comparison of 35 initiatives in 17 countries. Int J Cancer 122:1357–1367CrossRefPubMed
5.
go back to reference Schreuders EH, Ruco A, Rabeneck L, et al (2015) Colorectal cancer screening: a global overview of existing programmes. Gut Schreuders EH, Ruco A, Rabeneck L, et al (2015) Colorectal cancer screening: a global overview of existing programmes. Gut
6.
go back to reference Hewitson P, Glasziou P, Irwig L, Towler B, Watson E (2007) Screening for colorectal cancer using the faecal occult blood test, Hemoccult. Cochrane Database Syst Rev (1) Hewitson P, Glasziou P, Irwig L, Towler B, Watson E (2007) Screening for colorectal cancer using the faecal occult blood test, Hemoccult. Cochrane Database Syst Rev (1)
7.
go back to reference Pickhardt PJ, Choi JR, Hwang I et al (2003) Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 349:2191–2200CrossRefPubMed Pickhardt PJ, Choi JR, Hwang I et al (2003) Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 349:2191–2200CrossRefPubMed
8.
9.
go back to reference Plumb AA, Halligan S, Pendse DA, Taylor SA, Mallett S (2014) Sensitivity and specificity of CT colonography for the detection of colonic neoplasia after positive faecal occult blood testing: systematic review and meta-analysis. Eur Radiol Plumb AA, Halligan S, Pendse DA, Taylor SA, Mallett S (2014) Sensitivity and specificity of CT colonography for the detection of colonic neoplasia after positive faecal occult blood testing: systematic review and meta-analysis. Eur Radiol
10.
go back to reference Spada C, Stoker J, Alarcon O et al (2014) Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline. Endoscopy 46:897–915CrossRefPubMed Spada C, Stoker J, Alarcon O et al (2014) Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline. Endoscopy 46:897–915CrossRefPubMed
11.
go back to reference Spada C, Stoker J, Alarcon O et al (2015) Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline. Eur Radiol 25:331–345CrossRefPubMed Spada C, Stoker J, Alarcon O et al (2015) Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline. Eur Radiol 25:331–345CrossRefPubMed
13.
go back to reference Lin OS, Kozarek RA, Gluck M et al (2012) Preference for colonoscopy versus computerized tomographic colonography: a systematic review and meta-analysis of observational studies. J Gen Intern Med 27:1349–1360CrossRefPubMedPubMedCentral Lin OS, Kozarek RA, Gluck M et al (2012) Preference for colonoscopy versus computerized tomographic colonography: a systematic review and meta-analysis of observational studies. J Gen Intern Med 27:1349–1360CrossRefPubMedPubMedCentral
14.
go back to reference Taylor SA, Halligan S, Saunders BP, Bassett P, Vance M, Bartram CI (2003) Acceptance by patients of multidetector CT colonography compared with barium enema examinations, flexible sigmoidoscopy, and colonoscopy. AJR Am J Roentgenol 181:913–921CrossRefPubMed Taylor SA, Halligan S, Saunders BP, Bassett P, Vance M, Bartram CI (2003) Acceptance by patients of multidetector CT colonography compared with barium enema examinations, flexible sigmoidoscopy, and colonoscopy. AJR Am J Roentgenol 181:913–921CrossRefPubMed
15.
go back to reference Gluecker TM, Johnson CD, Harmsen WS et al (2003) Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination: prospective assessment of patient perceptions and preferences. Radiology 227:378–384CrossRefPubMed Gluecker TM, Johnson CD, Harmsen WS et al (2003) Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination: prospective assessment of patient perceptions and preferences. Radiology 227:378–384CrossRefPubMed
16.
go back to reference Stoop EM, de Haan MC, de Wijkerslooth TR, et al (2011) Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial. Lancet Oncol Stoop EM, de Haan MC, de Wijkerslooth TR, et al (2011) Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial. Lancet Oncol
17.
go back to reference Atkin W, Dadswell E, Wooldrage K et al (2013) Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial. Lancet 381:1194–1202CrossRefPubMed Atkin W, Dadswell E, Wooldrage K et al (2013) Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial. Lancet 381:1194–1202CrossRefPubMed
18.
go back to reference de Wijkerslooth TR, de Haan MC, Stoop EM, et al (2011) Burden of colonoscopy compared to non-cathartic CT-colonography in a colorectal cancer screening programme: randomised controlled trial. Gut de Wijkerslooth TR, de Haan MC, Stoop EM, et al (2011) Burden of colonoscopy compared to non-cathartic CT-colonography in a colorectal cancer screening programme: randomised controlled trial. Gut
19.
go back to reference von Wagner C, Ghanouni A, Halligan S et al (2012) Patient acceptability and psychologic consequences of CT colonography compared with those of colonoscopy: results from a multicenter randomized controlled trial of symptomatic patients. Radiology 263:723–731CrossRef von Wagner C, Ghanouni A, Halligan S et al (2012) Patient acceptability and psychologic consequences of CT colonography compared with those of colonoscopy: results from a multicenter randomized controlled trial of symptomatic patients. Radiology 263:723–731CrossRef
20.
go back to reference Logan RFA, Patnick J, Nickerson C, Coleman L, Rutter MD, von Wagner C (2012) Outcomes of the Bowel Cancer Screening Programme (BCSP) in England after the first 1 million tests. Gut 61(10):1439–1446 Logan RFA, Patnick J, Nickerson C, Coleman L, Rutter MD, von Wagner C (2012) Outcomes of the Bowel Cancer Screening Programme (BCSP) in England after the first 1 million tests. Gut 61(10):1439–1446
21.
go back to reference Plumb AA, Halligan S, Taylor SA, Burling D, Nickerson C, Patnick J (2013) CT colonography in the English Bowel Cancer Screening Programme: national survey of current practice. Clin Radiol 68(5):479–487 Plumb AA, Halligan S, Taylor SA, Burling D, Nickerson C, Patnick J (2013) CT colonography in the English Bowel Cancer Screening Programme: national survey of current practice. Clin Radiol 68(5):479–487
23.
go back to reference van Buuren S, Groothuis-Oudshoorn K (2011) mice: Multivariate imputation by chained equations in R. J Stat Softw 45:1–67CrossRef van Buuren S, Groothuis-Oudshoorn K (2011) mice: Multivariate imputation by chained equations in R. J Stat Softw 45:1–67CrossRef
24.
go back to reference Rubin DB (1987) Multiple imputation for nonresponse in surveys. J. Wiley & Sons, New YorkCrossRef Rubin DB (1987) Multiple imputation for nonresponse in surveys. J. Wiley & Sons, New YorkCrossRef
25.
go back to reference Spiegelhalter DJ (2005) Funnel plots for comparing institutional performance. Stat Med 24:1185–1202CrossRefPubMed Spiegelhalter DJ (2005) Funnel plots for comparing institutional performance. Stat Med 24:1185–1202CrossRefPubMed
26.
go back to reference Lee TJW, Rutter MD, Blanks RG et al (2012) Colonoscopy quality measures: experience from the NHS Bowel Cancer Screening Programme. Gut 61:1050–1057CrossRefPubMed Lee TJW, Rutter MD, Blanks RG et al (2012) Colonoscopy quality measures: experience from the NHS Bowel Cancer Screening Programme. Gut 61:1050–1057CrossRefPubMed
27.
go back to reference Plumb AA, Halligan S, Nickerson C et al (2014) Use of CT colonography in the English Bowel Cancer Screening Programme. Gut 63:964–973CrossRefPubMed Plumb AA, Halligan S, Nickerson C et al (2014) Use of CT colonography in the English Bowel Cancer Screening Programme. Gut 63:964–973CrossRefPubMed
28.
go back to reference Ball AJ, Rees CJ, Corfe BM, Riley SA (2015) Sedation practice and comfort during colonoscopy: lessons learnt from a national screening programme. Eur J Gastroenterol Hepatol 27:741–746CrossRefPubMed Ball AJ, Rees CJ, Corfe BM, Riley SA (2015) Sedation practice and comfort during colonoscopy: lessons learnt from a national screening programme. Eur J Gastroenterol Hepatol 27:741–746CrossRefPubMed
29.
go back to reference Stock C, Ihle P, Sieg A, Schubert I, Hoffmeister M, Brenner H (2013) Adverse events requiring hospitalization within 30 days after outpatient screening and nonscreening colonoscopies. Gastrointest Endosc 77:419–429CrossRefPubMed Stock C, Ihle P, Sieg A, Schubert I, Hoffmeister M, Brenner H (2013) Adverse events requiring hospitalization within 30 days after outpatient screening and nonscreening colonoscopies. Gastrointest Endosc 77:419–429CrossRefPubMed
30.
go back to reference Pox CP, Altenhofen L, Brenner H, Theilmeier A, Von Stillfried D, Schmiegel W (2012) Efficacy of a nationwide screening colonoscopy program for colorectal cancer. Gastroenterology 142:1460–1467, e2CrossRefPubMed Pox CP, Altenhofen L, Brenner H, Theilmeier A, Von Stillfried D, Schmiegel W (2012) Efficacy of a nationwide screening colonoscopy program for colorectal cancer. Gastroenterology 142:1460–1467, e2CrossRefPubMed
Metadata
Title
Patient experience of CT colonography and colonoscopy after fecal occult blood test in a national screening programme
Authors
Andrew A. Plumb
Alex Ghanouni
Colin J. Rees
Paul Hewitson
Claire Nickerson
Suzanne Wright
Stuart A. Taylor
Steve Halligan
Christian von Wagner
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 3/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4428-x

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