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Published in: European Radiology 3/2017

01-03-2017 | Head and Neck

Diagnostic efficacy and therapeutic impact of computed tomography in the evaluation of clinically suspected otosclerosis

Authors: Cristina Dudau, Fakhruddin Salim, Dan Jiang, Steve E. J. Connor

Published in: European Radiology | Issue 3/2017

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Abstract

Objective

To assess the diagnostic efficacy and therapeutic impact of CT in evaluating patients with clinically suspected otosclerosis.

Methods

CT scans performed over a 5-year period for clinically suspected otosclerosis were retrospectively reviewed. CT diagnoses were correlated with subsequent surgical management. For otosclerosis positive cases, clinically significant extensions of otosclerosis were correlated with audiometry and the diagnosis was correlated with surgical findings.

Results

Of 259 CT studies, 46 % of patients were positive, 49 % negative and 5 % equivocal for otosclerosis. A relevant alternative CT diagnosis was evident in 33 % of the negative studies. One targeted surgery was performed for every four CT studies. CT outcome influenced the decision to perform stapedectomy in 41 % CT-positive versus 4 % CT-negative patients. CT-positive ears for otosclerosis could not be predicted from baseline clinical or audiometric criteria. Those with endosteal extension demonstrated lower bone conduction thresholds presurgically. The positive predictive value of CT diagnosis of otosclerosis was 100 %.

Conclusions

CT demonstrated a high rate of clinically relevant diagnoses in both CT-positive and -negative for otosclerosis patients, and this frequently influenced surgical management. CT also added value by demonstrating relevant extensions of the otosclerotic foci, some of which were predictive of audiometric parameters.

Key Points

• CT demonstrates a high rate of alternative diagnoses in suspected otosclerosis, 1:3.
• CT results in a high rate of targeted surgery in suspected otosclerosis, 1:4.
• CT prevents exploratory surgery in suspected otosclerosis.
• Endosteal extension of otosclerosis is predictive of lower bone conduction tresholds presurgically.
• The PPV of CT diagnosis of otosclerosis was 100 %.
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Metadata
Title
Diagnostic efficacy and therapeutic impact of computed tomography in the evaluation of clinically suspected otosclerosis
Authors
Cristina Dudau
Fakhruddin Salim
Dan Jiang
Steve E. J. Connor
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 3/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4446-8

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