Skip to main content
Top
Published in: European Radiology 2/2017

01-02-2017 | Cardiac

Value of a noise-optimized virtual monoenergetic reconstruction technique in dual-energy CT for planning of transcatheter aortic valve replacement

Authors: Simon S. Martin, Moritz H. Albrecht, Julian L. Wichmann, Kristina Hüsers, Jan-Erik Scholtz, Christian Booz, Boris Bodelle, Ralf W. Bauer, Sarah C. Metzger, Thomas J. Vogl, Thomas Lehnert

Published in: European Radiology | Issue 2/2017

Login to get access

Abstract

Objectives

To evaluate objective and subjective image quality of a noise-optimized virtual monoenergetic imaging (VMI+) reconstruction technique in dual-energy computed tomography (DECT) angiography prior to transcatheter aortic valve replacement (TAVR).

Methods

Datasets of 47 patients (35 men; 64.1 ± 10.9 years) who underwent DECT angiography of heart and vascular access prior to TAVR were reconstructed with standard linear blending (F_0.5), VMI+, and traditional monoenergetic (VMI) algorithms in 10-keV intervals from 40–100 keV. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of 564 arterial segments were evaluated. Subjective analysis was rated by three blinded observers using a Likert scale.

Results

Mean SNR and CNR were highest in 40 keV VMI+ series (SNR, 27.8 ± 13.0; CNR, 26.3 ± 12.7), significantly (all p < 0.001) superior to all VMI series, which showed highest values at 70 keV (SNR, 18.5 ± 7.6; CNR, 16.0 ± 7.4), as well as linearly-blended F_0.5 series (SNR, 16.8 ± 7.3; CNR, 13.6 ± 6.9). Highest subjective image quality scores were observed for 40, 50, and 60 keV VMI+ reconstructions (all p > 0.05), significantly superior to all VMI and standard linearly-blended images (all p < 0.01).

Conclusions

Low-keV VMI+ reconstructions significantly increase CNR and SNR compared to VMI and standard linear-blending image reconstruction and improve subjective image quality in preprocedural DECT angiography in the context of TAVR planning.

Key Points

VMI+ combines increased contrast with reduced image noise.
VMI+ shows substantially less image noise than traditional VMI.
40-keV reconstructions show highest SNR/CNR of the aortic and iliofemoral access route.
Observers overall prefer 60 keV VMI+ images.
VMI+ DECT imaging helps improve image quality for TAVR planning.
Literature
1.
go back to reference Blanke P, Spira EM, Ionasec R et al (2014) Semiautomated quantification of aortic annulus dimensions on cardiac CT for TAVR. JACC Cardiovasc Imaging 7:320–322CrossRefPubMed Blanke P, Spira EM, Ionasec R et al (2014) Semiautomated quantification of aortic annulus dimensions on cardiac CT for TAVR. JACC Cardiovasc Imaging 7:320–322CrossRefPubMed
2.
go back to reference Blanke P, Schoepf UJ, Leipsic JA (2013) CT in transcatheter aortic valve replacement. Radiology 269:650–669CrossRefPubMed Blanke P, Schoepf UJ, Leipsic JA (2013) CT in transcatheter aortic valve replacement. Radiology 269:650–669CrossRefPubMed
3.
go back to reference Wichmann JL, Varga-Szemes A, Suranyi P et al (2015) Transcatheter aortic valve replacement: imaging techniques for aortic root sizing. J Thorac Imaging 30:349–358 Wichmann JL, Varga-Szemes A, Suranyi P et al (2015) Transcatheter aortic valve replacement: imaging techniques for aortic root sizing. J Thorac Imaging 30:349–358
4.
go back to reference Apfaltrer P, Henzler T, Blanke P, Krazinski AW, Silverman JR, Schoepf UJ (2013) Computed tomography for planning transcatheter aortic valve replacement. J Thorac Imaging 28:231–239CrossRefPubMed Apfaltrer P, Henzler T, Blanke P, Krazinski AW, Silverman JR, Schoepf UJ (2013) Computed tomography for planning transcatheter aortic valve replacement. J Thorac Imaging 28:231–239CrossRefPubMed
5.
go back to reference Roller FC, Schuhbaeck A, Achenbach S, Krombach GA, Schneider C (2015) CT before transcatheter aortic valve implantation: value of venous phase imaging for detection and interpretation of findings with impact on the TAVI procedure. J Cardiovasc Comput Tomogr 9:422–427 Roller FC, Schuhbaeck A, Achenbach S, Krombach GA, Schneider C (2015) CT before transcatheter aortic valve implantation: value of venous phase imaging for detection and interpretation of findings with impact on the TAVI procedure. J Cardiovasc Comput Tomogr 9:422–427
6.
go back to reference Schuhbaeck A, Achenbach S, Pflederer T et al (2014) Reproducibility of aortic annulus measurements by computed tomography. Eur Radiol 24:1878–1888CrossRefPubMed Schuhbaeck A, Achenbach S, Pflederer T et al (2014) Reproducibility of aortic annulus measurements by computed tomography. Eur Radiol 24:1878–1888CrossRefPubMed
7.
go back to reference Rixe J, Schuhbaeck A, Liebetrau C et al (2012) Multi-detector computed tomography is equivalent to trans-oesophageal echocardiography for the assessment of the aortic annulus before transcatheter aortic valve implantation. Eur Radiol 22:2662–2669CrossRefPubMed Rixe J, Schuhbaeck A, Liebetrau C et al (2012) Multi-detector computed tomography is equivalent to trans-oesophageal echocardiography for the assessment of the aortic annulus before transcatheter aortic valve implantation. Eur Radiol 22:2662–2669CrossRefPubMed
8.
go back to reference Blanke P, Russe M, Leipsic J et al (2012) Conformational pulsatile changes of the aortic annulus: impact on prosthesis sizing by computed tomography for transcatheter aortic valve replacement. JACC Cardiovasc Interv 5:984–994CrossRefPubMed Blanke P, Russe M, Leipsic J et al (2012) Conformational pulsatile changes of the aortic annulus: impact on prosthesis sizing by computed tomography for transcatheter aortic valve replacement. JACC Cardiovasc Interv 5:984–994CrossRefPubMed
9.
go back to reference Vlahos I, Chung R, Nair A, Morgan R (2012) Dual-energy CT: vascular applications. AJR Am J Roentgenol 199:S87–S97CrossRefPubMed Vlahos I, Chung R, Nair A, Morgan R (2012) Dual-energy CT: vascular applications. AJR Am J Roentgenol 199:S87–S97CrossRefPubMed
10.
go back to reference Marin D, Fananapazir G, Mileto A, Choudhury KR, Wilson JM, Nelson RC (2014) Dual-energy multi-detector row CT with virtual monochromatic imaging for improving patient-to-patient uniformity of aortic enhancement during CT angiography: an in vitro and in vivo study. Radiology 272:895–902CrossRefPubMed Marin D, Fananapazir G, Mileto A, Choudhury KR, Wilson JM, Nelson RC (2014) Dual-energy multi-detector row CT with virtual monochromatic imaging for improving patient-to-patient uniformity of aortic enhancement during CT angiography: an in vitro and in vivo study. Radiology 272:895–902CrossRefPubMed
11.
go back to reference Schneider D, Apfaltrer P, Sudarski S et al (2014) Optimization of kiloelectron volt settings in cerebral and cervical dual-energy CT angiography determined with virtual monoenergetic imaging. Acad Radiol 21:431–436CrossRefPubMed Schneider D, Apfaltrer P, Sudarski S et al (2014) Optimization of kiloelectron volt settings in cerebral and cervical dual-energy CT angiography determined with virtual monoenergetic imaging. Acad Radiol 21:431–436CrossRefPubMed
12.
go back to reference Apfaltrer P, Sudarski S, Schneider D et al (2014) Value of monoenergetic low-kV dual energy CT datasets for improved image quality of CT pulmonary angiography. Eur J Radiol 83:322–328CrossRefPubMed Apfaltrer P, Sudarski S, Schneider D et al (2014) Value of monoenergetic low-kV dual energy CT datasets for improved image quality of CT pulmonary angiography. Eur J Radiol 83:322–328CrossRefPubMed
13.
go back to reference Sudarski S, Apfaltrer P, Nance JW Jr et al (2013) Optimization of keV-settings in abdominal and lower extremity dual-source dual-energy CT angiography determined with virtual monoenergetic imaging. Eur J Radiol 82:e574–e581CrossRefPubMed Sudarski S, Apfaltrer P, Nance JW Jr et al (2013) Optimization of keV-settings in abdominal and lower extremity dual-source dual-energy CT angiography determined with virtual monoenergetic imaging. Eur J Radiol 82:e574–e581CrossRefPubMed
14.
go back to reference Schabel C, Bongers M, Sedlmair M et al (2014) Assessment of the hepatic veins in poor contrast conditions using dual energy CT: evaluation of a novel monoenergetic extrapolation software algorithm. Röfo 186:591–597PubMed Schabel C, Bongers M, Sedlmair M et al (2014) Assessment of the hepatic veins in poor contrast conditions using dual energy CT: evaluation of a novel monoenergetic extrapolation software algorithm. Röfo 186:591–597PubMed
15.
go back to reference Beeres M, Trommer J, Frellesen C et al (2016) Evaluation of different keV-settings in dual-energy CT angiography of the aorta using advanced image-based virtual monoenergetic imaging. Int J Cardiovasc Imaging 32:137–144 Beeres M, Trommer J, Frellesen C et al (2016) Evaluation of different keV-settings in dual-energy CT angiography of the aorta using advanced image-based virtual monoenergetic imaging. Int J Cardiovasc Imaging 32:137–144
16.
go back to reference Wichmann JL, Gillott MR, De Cecco CN et al (2016) Dual-energy CT angiography of the lower extremity run-off: impact of noise-optimized virtual monochromatic imaging on image quality and diagnostic accuracy. Invest Radiol 51:139–146 Wichmann JL, Gillott MR, De Cecco CN et al (2016) Dual-energy CT angiography of the lower extremity run-off: impact of noise-optimized virtual monochromatic imaging on image quality and diagnostic accuracy. Invest Radiol 51:139–146
17.
go back to reference Behrendt FF, Schmidt B, Plumhans C et al (2009) Image fusion in dual energy computed tomography: effect on contrast enhancement, signal-to-noise ratio and image quality in computed tomography angiography. Investig Radiol 44:1–6CrossRef Behrendt FF, Schmidt B, Plumhans C et al (2009) Image fusion in dual energy computed tomography: effect on contrast enhancement, signal-to-noise ratio and image quality in computed tomography angiography. Investig Radiol 44:1–6CrossRef
18.
go back to reference Yu L, Leng S, McCollough CH (2012) Dual-energy CT-based monochromatic imaging. AJR Am J Roentgenol 199:S9–S15CrossRefPubMed Yu L, Leng S, McCollough CH (2012) Dual-energy CT-based monochromatic imaging. AJR Am J Roentgenol 199:S9–S15CrossRefPubMed
19.
go back to reference Grant KL, Flohr TG, Krauss B, Sedlmair M, Thomas C, Schmidt B (2014) Assessment of an advanced image-based technique to calculate virtual monoenergetic computed tomographic images from a dual-energy examination to improve contrast-to-noise ratio in examinations using iodinated contrast media. Investig Radiol 49:586–592CrossRef Grant KL, Flohr TG, Krauss B, Sedlmair M, Thomas C, Schmidt B (2014) Assessment of an advanced image-based technique to calculate virtual monoenergetic computed tomographic images from a dual-energy examination to improve contrast-to-noise ratio in examinations using iodinated contrast media. Investig Radiol 49:586–592CrossRef
20.
go back to reference Wichmann JL, Noske EM, Kraft J et al (2014) Virtual monoenergetic dual-energy computed tomography: optimization of kiloelectron volt settings in head and neck cancer. Investig Radiol 49:735–741CrossRef Wichmann JL, Noske EM, Kraft J et al (2014) Virtual monoenergetic dual-energy computed tomography: optimization of kiloelectron volt settings in head and neck cancer. Investig Radiol 49:735–741CrossRef
21.
go back to reference Sudarski S, Apfaltrer P, Nance JW Jr et al (2014) Objective and subjective image quality of liver parenchyma and hepatic metastases with virtual monoenergetic dual-source dual-energy CT reconstructions: an analysis in patients with gastrointestinal stromal tumor. Acad Radiol 21:514–522CrossRefPubMed Sudarski S, Apfaltrer P, Nance JW Jr et al (2014) Objective and subjective image quality of liver parenchyma and hepatic metastases with virtual monoenergetic dual-source dual-energy CT reconstructions: an analysis in patients with gastrointestinal stromal tumor. Acad Radiol 21:514–522CrossRefPubMed
22.
go back to reference Wichmann JL, Arbaciauskaite R, Kerl JM et al (2014) Evaluation of monoenergetic late iodine enhancement dual-energy computed tomography for imaging of chronic myocardial infarction. Eur Radiol 24:1211–1218CrossRefPubMed Wichmann JL, Arbaciauskaite R, Kerl JM et al (2014) Evaluation of monoenergetic late iodine enhancement dual-energy computed tomography for imaging of chronic myocardial infarction. Eur Radiol 24:1211–1218CrossRefPubMed
23.
go back to reference Leng S, Yu L, Fletcher JG, McCollough CH (2015) Maximizing iodine contrast-to-noise ratios in abdominal CT imaging through use of energy domain noise reduction and virtual monoenergetic dual-energy CT. Radiology 276:562–570CrossRefPubMedPubMedCentral Leng S, Yu L, Fletcher JG, McCollough CH (2015) Maximizing iodine contrast-to-noise ratios in abdominal CT imaging through use of energy domain noise reduction and virtual monoenergetic dual-energy CT. Radiology 276:562–570CrossRefPubMedPubMedCentral
24.
go back to reference Bongers MN, Schabel C, Krauss B et al (2015) Noise-optimized virtual monoenergetic images and iodine maps for the detection of venous thrombosis in second-generation dual-energy CT (DECT): an ex vivo phantom study. Eur Radiol 25:1655–1664CrossRefPubMed Bongers MN, Schabel C, Krauss B et al (2015) Noise-optimized virtual monoenergetic images and iodine maps for the detection of venous thrombosis in second-generation dual-energy CT (DECT): an ex vivo phantom study. Eur Radiol 25:1655–1664CrossRefPubMed
25.
go back to reference Albrecht MH, Scholtz JE, Kraft J et al (2015) Assessment of an advanced monoenergetic reconstruction technique in dual-energy computed tomography of head and neck cancer. Eur Radiol 25:2493–2501CrossRefPubMed Albrecht MH, Scholtz JE, Kraft J et al (2015) Assessment of an advanced monoenergetic reconstruction technique in dual-energy computed tomography of head and neck cancer. Eur Radiol 25:2493–2501CrossRefPubMed
26.
go back to reference Delesalle MA, Pontana F, Duhamel A et al (2013) Spectral optimization of chest CT angiography with reduced iodine load: experience in 80 patients evaluated with dual-source, dual-energy CT. Radiology 267:256–266CrossRefPubMed Delesalle MA, Pontana F, Duhamel A et al (2013) Spectral optimization of chest CT angiography with reduced iodine load: experience in 80 patients evaluated with dual-source, dual-energy CT. Radiology 267:256–266CrossRefPubMed
27.
go back to reference Dubourg B, Caudron J, Lestrat JP et al (2014) Single-source dual-energy CT angiography with reduced iodine load in patients referred for aortoiliofemoral evaluation before transcatheter aortic valve implantation: impact on image quality and radiation dose. Eur Radiol 24:2659–2668CrossRefPubMed Dubourg B, Caudron J, Lestrat JP et al (2014) Single-source dual-energy CT angiography with reduced iodine load in patients referred for aortoiliofemoral evaluation before transcatheter aortic valve implantation: impact on image quality and radiation dose. Eur Radiol 24:2659–2668CrossRefPubMed
28.
go back to reference Bamberg F, Dierks A, Nikolaou K, Reiser MF, Becker CR, Johnson TR (2011) Metal artifact reduction by dual energy computed tomography using monoenergetic extrapolation. Eur Radiol 21:1424–1429CrossRefPubMed Bamberg F, Dierks A, Nikolaou K, Reiser MF, Becker CR, Johnson TR (2011) Metal artifact reduction by dual energy computed tomography using monoenergetic extrapolation. Eur Radiol 21:1424–1429CrossRefPubMed
29.
go back to reference Meinel FG, Bischoff B, Zhang Q, Bamberg F, Reiser MF, Johnson TR (2012) Metal artifact reduction by dual-energy computed tomography using energetic extrapolation: a systematically optimized protocol. Investig Radiol 47:406–414CrossRef Meinel FG, Bischoff B, Zhang Q, Bamberg F, Reiser MF, Johnson TR (2012) Metal artifact reduction by dual-energy computed tomography using energetic extrapolation: a systematically optimized protocol. Investig Radiol 47:406–414CrossRef
30.
go back to reference Mangold S, Cannaò PM, Schoepf UJ et al (2016) Impact of an advanced image-based monoenergetic reconstruction algorithm on coronary stent visualization using 3rd generation dual-source dual-energy CT: a phantom study. Eur Radiol 26:1871–1878 Mangold S, Cannaò PM, Schoepf UJ et al (2016) Impact of an advanced image-based monoenergetic reconstruction algorithm on coronary stent visualization using 3rd generation dual-source dual-energy CT: a phantom study. Eur Radiol 26:1871–1878
Metadata
Title
Value of a noise-optimized virtual monoenergetic reconstruction technique in dual-energy CT for planning of transcatheter aortic valve replacement
Authors
Simon S. Martin
Moritz H. Albrecht
Julian L. Wichmann
Kristina Hüsers
Jan-Erik Scholtz
Christian Booz
Boris Bodelle
Ralf W. Bauer
Sarah C. Metzger
Thomas J. Vogl
Thomas Lehnert
Publication date
01-02-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 2/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4422-3

Other articles of this Issue 2/2017

European Radiology 2/2017 Go to the issue