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European Radiology
Published in: European Radiology 9/2016

01-09-2016 | Breast

Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance

Authors: Dan-Dan Li, Hui-Xiong Xu, Le-Hang Guo, Xiao-Wan Bo, Xiao-Long Li, Rong Wu, Jun-Mei Xu, Yi-Feng Zhang, Kun Zhang

Published in: European Radiology | Issue 9/2016

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Abstract

Objectives

To evaluate the diagnostic performance of a new method of combined two-dimensional shear wave elastography (i.e. virtual touch imaging quantification, VTIQ) and ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) in the differential diagnosis of breast lesions.

Materials and methods

From September 2014 to December 2014, 276 patients with 296 pathologically proven breast lesions were enrolled in this study. The conventional US images were interpreted by two independent readers. The diagnosis performances of BI-RADS and combined BI-RADS and VTIQ were evaluated, including the area under the receiver operating characteristic curve (AUROC), sensitivity and specificity. Observer consistency was also evaluated.

Results

Pathologically, 212 breast lesions were benign and 84 were malignant. Compared with BI-RADS alone, the AUROCs and specificities of the combined method for both readers increased significantly (AUROC: 0.862 vs. 0.693 in reader 1, 0.861 vs. 0.730 in reader 2; specificity: 91.5 % vs. 38.7 % in reader 1, 94.8 % vs. 47.2 % in reader 2; all P < .05). The Kappa value between the two readers for BI-RADS assessment was 0.614, and 0.796 for the combined method.

Conclusion

The combined VTIQ and BI-RADS had a better diagnostic performance in the diagnosis of breast lesions in comparison with BI-RADS alone.

Key Points

• Combination of conventional ultrasound and elastography distinguishes breast cancers more effectively.
• Combination of conventional ultrasound and elastography increases observer consistency.
• BI-RADS weights more than the 2D-SWE with an increase in malignancy probability.
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Metadata
Title
Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance
Authors
Dan-Dan Li
Hui-Xiong Xu
Le-Hang Guo
Xiao-Wan Bo
Xiao-Long Li
Rong Wu
Jun-Mei Xu
Yi-Feng Zhang
Kun Zhang
Publication date
01-09-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 9/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-4163-8

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