Skip to main content
Top
Published in: European Radiology 6/2016

01-06-2016 | Vascular-Interventional

Endovascular management of massive post-partum haemorrhage in abnormal placental implantation deliveries

Authors: Alberto Rebonato, Stefano Mosca, Matthias Fischer, Sandro Gerli, Gianluigi Orgera, Luigina Graziosi, Daniele Maiettini, Gian Carlo Di Renzo, Giorgio Epicoco, Miltiadis Krokidis, Michele Rossi, Michele Scialpi

Published in: European Radiology | Issue 6/2016

Login to get access

Abstract

Objectives

To retrospectively evaluate safety and efficacy of pelvic artery embolisation (PAE) in post-partum haemorrhage (PPH) in abnormal placental implantation (API) deliveries.

Methods

From January 2009 to November 2013, 12 patients with API and intractable intraoperative PPH underwent PAE after caesarean delivery to control a haemorrhage (in four of these cases after hysterectomy). Arterial access was obtained prior to the delivery; PAE was performed in the obstetrics operating room by an interventional radiologist that was present with an interventional radiology (IR) team during the delivery.

Results

PAE was successful in preventing bleeding and avoid hysterectomy in four cases (group A). Uterine atony and disseminated intravascular coagulation caused failure of PAE requiring hysterectomy in four patients (group B). PAE prevented bleeding post-hysterectomy in the remaining four cases (group C). Technical success (cessation of contrast extravasation on angiography or occlusion of the selected artery) was 100 %. Maternal and foetal mortality and morbidity were 0 %.

Conclusions

PAE is a minimal invasive technique that may help to prevent hysterectomy and control PPH in API pregnancies without complications. Embolisation should be performed on an emergency basis. For such cases, an IR team on standby in the obstetrics theatre may be useful to prevent hysterectomy, blood loss and limit morbidity.

Key Points

Endovascular treatment is a validated technique in post-partum haemorrhage.
Abnormal placental implantation is a risk factor for post-partum haemorrhage.
We propose an interventional radiologist standby in the delivery room.
Literature
1.
go back to reference American College of Obstetricians and Gynecologists (2006) ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 108:1039–1047CrossRef American College of Obstetricians and Gynecologists (2006) ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 108:1039–1047CrossRef
2.
go back to reference Sheldon W, Blum J, Vogel J, Souza J, Gulmezoglu A, Winikoff B et al (2014) Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 121:5–13CrossRefPubMed Sheldon W, Blum J, Vogel J, Souza J, Gulmezoglu A, Winikoff B et al (2014) Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 121:5–13CrossRefPubMed
3.
go back to reference Roberts WE (1995) Emergent obstetric management of obstetric hemorrhage. Obstet Gynecol Clin N Am 22:283–302 Roberts WE (1995) Emergent obstetric management of obstetric hemorrhage. Obstet Gynecol Clin N Am 22:283–302
6.
go back to reference Sofiah S, Med M, Late Y, Fung C et al (2009) Placenta accreta: clinical risk factors, accuracy of antenatal diagnosis and effect on pregnancy outcome. Med J Malaysia 64:298–302PubMed Sofiah S, Med M, Late Y, Fung C et al (2009) Placenta accreta: clinical risk factors, accuracy of antenatal diagnosis and effect on pregnancy outcome. Med J Malaysia 64:298–302PubMed
7.
go back to reference Hwang SM, Jeon GS, Kim MD, Kim SH, Lee JT, Choi MJ (2013) Transcatheter arterial embolisation for the management of obstetric haemorrhage associated with placental abnormality in 40 cases. Eur Radiol 23:766–773CrossRefPubMed Hwang SM, Jeon GS, Kim MD, Kim SH, Lee JT, Choi MJ (2013) Transcatheter arterial embolisation for the management of obstetric haemorrhage associated with placental abnormality in 40 cases. Eur Radiol 23:766–773CrossRefPubMed
8.
go back to reference Gerli S, Favilli A, Affronti G et al (2013) Prophylactic arterial catheterization in the management of high risk patients for obstetric haemorrhage. Eur Rev Med Pharmacol Sci 17:2822–2826PubMed Gerli S, Favilli A, Affronti G et al (2013) Prophylactic arterial catheterization in the management of high risk patients for obstetric haemorrhage. Eur Rev Med Pharmacol Sci 17:2822–2826PubMed
9.
go back to reference Rebonato A, D’Andrea A, Scialpi M (2013) Painless but problematic. Imaging modalities were useful in the diagnosis and treatment of an unusual tumor. Am J Obstet Gynecol 208:237.e1–237.e2CrossRef Rebonato A, D’Andrea A, Scialpi M (2013) Painless but problematic. Imaging modalities were useful in the diagnosis and treatment of an unusual tumor. Am J Obstet Gynecol 208:237.e1–237.e2CrossRef
10.
go back to reference Park KJ, Shin JH, Yoon HK, Gwon DI, Ko GY, Sung KB (2015) Postpartum haemorrhage from extravation or pseudoaneurysm: efficacy of transcatheter arterial embolization using N-Butyl Cyanoacrylate and comparision with gelatine sponge particle. J Vasc Interv Radiol 26:154–161CrossRefPubMed Park KJ, Shin JH, Yoon HK, Gwon DI, Ko GY, Sung KB (2015) Postpartum haemorrhage from extravation or pseudoaneurysm: efficacy of transcatheter arterial embolization using N-Butyl Cyanoacrylate and comparision with gelatine sponge particle. J Vasc Interv Radiol 26:154–161CrossRefPubMed
11.
go back to reference Kirby JM, Kachura JR, Rajan DK, Sniderman KW, Simons ME, Windrim RC et al (2009) Arterial embolization for primary postpartum hemorrhage. J Vasc Interv Radiol 20:1036–1045CrossRefPubMed Kirby JM, Kachura JR, Rajan DK, Sniderman KW, Simons ME, Windrim RC et al (2009) Arterial embolization for primary postpartum hemorrhage. J Vasc Interv Radiol 20:1036–1045CrossRefPubMed
12.
go back to reference Sacks D, McClenny TE, Cardella JF, Lewis CA (2003) Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 14:S199–S202CrossRefPubMed Sacks D, McClenny TE, Cardella JF, Lewis CA (2003) Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 14:S199–S202CrossRefPubMed
13.
go back to reference Hansch E, Chitkara U, McAlpine J, El-Sayed Y, Dake MD, Razavi MK (1999) Pelvic arterial embolization for control of obstetric hemorrhage: a five-year experience. Am J Obstet Gynecol 180:1454–1460CrossRefPubMed Hansch E, Chitkara U, McAlpine J, El-Sayed Y, Dake MD, Razavi MK (1999) Pelvic arterial embolization for control of obstetric hemorrhage: a five-year experience. Am J Obstet Gynecol 180:1454–1460CrossRefPubMed
14.
go back to reference Li Q, Yang ZQ, Mohammed W, Feng YL, Shi HB, Zhou X (2014) Prophylactic uterine artery embolization assisted cesarean section for the prevention of intrapartum hemorrhage in high-risk patients. Cardiovasc Intervent Radiol 37:1458–1463CrossRefPubMedPubMedCentral Li Q, Yang ZQ, Mohammed W, Feng YL, Shi HB, Zhou X (2014) Prophylactic uterine artery embolization assisted cesarean section for the prevention of intrapartum hemorrhage in high-risk patients. Cardiovasc Intervent Radiol 37:1458–1463CrossRefPubMedPubMedCentral
15.
go back to reference Chou YJ, Cheng YF, Shen CC, Hsu TY, Chang SY, Kung FT (2004) Failure of uterine arterial embolization: placenta accreta with profuse postpartum hemorrhage. Acta Obstet Gynecol Scand 83:688–690CrossRefPubMed Chou YJ, Cheng YF, Shen CC, Hsu TY, Chang SY, Kung FT (2004) Failure of uterine arterial embolization: placenta accreta with profuse postpartum hemorrhage. Acta Obstet Gynecol Scand 83:688–690CrossRefPubMed
16.
go back to reference La Folie T, Vidal V, Mehanna M et al (2007) Results of endovascular treatment in cases of abnormal placentation with post-partum hemorrhage. J Obstet Gynaecol Res 33:624–630CrossRefPubMed La Folie T, Vidal V, Mehanna M et al (2007) Results of endovascular treatment in cases of abnormal placentation with post-partum hemorrhage. J Obstet Gynaecol Res 33:624–630CrossRefPubMed
17.
go back to reference Kim YJ, Yoon CJ, Seong NJ et al (2013) Failed pelvic arterial embolization for postpartum hemorrhage: clinical outcomes and predictive factors. J Vasc Interv Radiol 24:703–709CrossRefPubMed Kim YJ, Yoon CJ, Seong NJ et al (2013) Failed pelvic arterial embolization for postpartum hemorrhage: clinical outcomes and predictive factors. J Vasc Interv Radiol 24:703–709CrossRefPubMed
18.
go back to reference Oei PL, Chua S, Tan L, Ratnam SS, Arulkumaran S (1998) Arterial embolization for bleeding following hysterectomy for intractable postpartum hemorrhage. Int J Gynaecol Obstet 62:83–86CrossRefPubMed Oei PL, Chua S, Tan L, Ratnam SS, Arulkumaran S (1998) Arterial embolization for bleeding following hysterectomy for intractable postpartum hemorrhage. Int J Gynaecol Obstet 62:83–86CrossRefPubMed
19.
go back to reference Maassen MS, Lambers MD, Tutein Nolthenius RP, van der Valk PH, Elgersma OE (2009) Complications and failure of uterine artery embolisation for intractable postpartum haemorrhage. BJOG 116:55–61CrossRefPubMed Maassen MS, Lambers MD, Tutein Nolthenius RP, van der Valk PH, Elgersma OE (2009) Complications and failure of uterine artery embolisation for intractable postpartum haemorrhage. BJOG 116:55–61CrossRefPubMed
20.
go back to reference Rebonato A, Auci A, Sanguinetti F et al (2014) Embolization of the periprostatic venous plexus for erectile dysfunction resulting from venous leakage. J Vasc Interv Radiol 25:866–872CrossRefPubMed Rebonato A, Auci A, Sanguinetti F et al (2014) Embolization of the periprostatic venous plexus for erectile dysfunction resulting from venous leakage. J Vasc Interv Radiol 25:866–872CrossRefPubMed
21.
go back to reference Lopera J, Suri R, Kroma GM, Garza-Berlanga A, Thomas J (2013) Role of interventional procedures in obstetrics/gynecology. Radiol Clin N Am 51:1049–1066CrossRefPubMed Lopera J, Suri R, Kroma GM, Garza-Berlanga A, Thomas J (2013) Role of interventional procedures in obstetrics/gynecology. Radiol Clin N Am 51:1049–1066CrossRefPubMed
22.
go back to reference Vedantham S, Goodwin SC, McLucas B, Mohr G (1997) Uterine artery embolization: an underused method of controlling pelvic hemorrhage. Am J Obstet Gynecol 176:938–948CrossRefPubMed Vedantham S, Goodwin SC, McLucas B, Mohr G (1997) Uterine artery embolization: an underused method of controlling pelvic hemorrhage. Am J Obstet Gynecol 176:938–948CrossRefPubMed
23.
go back to reference Cottier JP, Fignon A, Tranquart F, Herbreteau D (2002) Uterine necrosis after arterial embolization for postpartum hemorrhage. Obstet Gynecol 100:1074–1077PubMed Cottier JP, Fignon A, Tranquart F, Herbreteau D (2002) Uterine necrosis after arterial embolization for postpartum hemorrhage. Obstet Gynecol 100:1074–1077PubMed
24.
go back to reference Sergent F, Resch B, Verspyck E, Rachet B, Clavier E, Marpeau L (2004) Intractable postpartum haemorrhages: where is the place of vascular ligations, emergency peripartum hysterectomy or arterial embolization? Gynecol Obstet Fertil 32:320–329CrossRefPubMed Sergent F, Resch B, Verspyck E, Rachet B, Clavier E, Marpeau L (2004) Intractable postpartum haemorrhages: where is the place of vascular ligations, emergency peripartum hysterectomy or arterial embolization? Gynecol Obstet Fertil 32:320–329CrossRefPubMed
25.
go back to reference Kanematsu M, Watanabe H, Kondo H et al (2011) Postpartum hemorrhage in coagulopathic patients: preliminary experience with uterine arterial embolization with N-butyl cyanoacrylate. J Vasc Interv Radiol 22:1773–1776CrossRefPubMed Kanematsu M, Watanabe H, Kondo H et al (2011) Postpartum hemorrhage in coagulopathic patients: preliminary experience with uterine arterial embolization with N-butyl cyanoacrylate. J Vasc Interv Radiol 22:1773–1776CrossRefPubMed
26.
go back to reference Bodner LJ, Nosher JL, Gribbin C, Siegel RL, Beale S, Scorza W (2006) Balloon-assisted occlusion of the internal iliac arteries in patients with placenta accreta/percreta. Cardiovasc Intervent Radiol 29:354–361CrossRefPubMed Bodner LJ, Nosher JL, Gribbin C, Siegel RL, Beale S, Scorza W (2006) Balloon-assisted occlusion of the internal iliac arteries in patients with placenta accreta/percreta. Cardiovasc Intervent Radiol 29:354–361CrossRefPubMed
27.
go back to reference Clausen C, Stensballe J, Albrechtsen CK, Hansen MA, Lönn L, Langhoff-Roos J (2013) Balloon occlusion of the internal iliac arteries in the multidisciplinary management of placenta percreta. Acta Obstet Gynecol Scand 92:386–391CrossRefPubMed Clausen C, Stensballe J, Albrechtsen CK, Hansen MA, Lönn L, Langhoff-Roos J (2013) Balloon occlusion of the internal iliac arteries in the multidisciplinary management of placenta percreta. Acta Obstet Gynecol Scand 92:386–391CrossRefPubMed
28.
go back to reference Kidney DD, Nguyen AM, Ahdoot D, Bickmore D, Deutsch LS, Majors C (2001) Prophylactic perioperative hypogastric artery balloon occlusion in abnormal placentation. AJR Am J Roentgenol 176:1521–1524CrossRefPubMed Kidney DD, Nguyen AM, Ahdoot D, Bickmore D, Deutsch LS, Majors C (2001) Prophylactic perioperative hypogastric artery balloon occlusion in abnormal placentation. AJR Am J Roentgenol 176:1521–1524CrossRefPubMed
29.
go back to reference Masamoto H, Uehara H, Gibo M, Okubo E, Sakumoto K, Aoki Y (2009) Elective use of aortic balloon occlusion in cesarean hysterectomy for placenta previa percreta. Gynecol Obstet Investig 67:92–95CrossRef Masamoto H, Uehara H, Gibo M, Okubo E, Sakumoto K, Aoki Y (2009) Elective use of aortic balloon occlusion in cesarean hysterectomy for placenta previa percreta. Gynecol Obstet Investig 67:92–95CrossRef
30.
go back to reference Ott LK, Hoffman LA, Hravnak M (2011) Intrahospital transport to the radiology department: risk for adverse events, nursing surveillance, utilization of a MET and practice implications. J Radiol Nurs 30:49–52CrossRefPubMedPubMedCentral Ott LK, Hoffman LA, Hravnak M (2011) Intrahospital transport to the radiology department: risk for adverse events, nursing surveillance, utilization of a MET and practice implications. J Radiol Nurs 30:49–52CrossRefPubMedPubMedCentral
31.
go back to reference Jaik NP, Umakanthan R, Leacche M et al (2011) Current status of hybrid coronary revascularization. Expert Rev Cardiovasc Ther 9:1331–1337CrossRefPubMed Jaik NP, Umakanthan R, Leacche M et al (2011) Current status of hybrid coronary revascularization. Expert Rev Cardiovasc Ther 9:1331–1337CrossRefPubMed
32.
go back to reference Iihara K, Satow T, Matsushige T et al (2013) Hybrid operating room for the treatment of complex neurovascular and brachiocephalic lesions. J Stroke Cerebrovasc Dis 22:e277–e285CrossRefPubMed Iihara K, Satow T, Matsushige T et al (2013) Hybrid operating room for the treatment of complex neurovascular and brachiocephalic lesions. J Stroke Cerebrovasc Dis 22:e277–e285CrossRefPubMed
33.
go back to reference Clark A, Farber MK, Sviggum H, Camann W (2013) Cesarean delivery in the hybrid operating suite: a promising new location for high-risk obstetric procedures. Anesth Analg 117:1187–1189CrossRefPubMed Clark A, Farber MK, Sviggum H, Camann W (2013) Cesarean delivery in the hybrid operating suite: a promising new location for high-risk obstetric procedures. Anesth Analg 117:1187–1189CrossRefPubMed
34.
35.
go back to reference Yamasaki Y, Morita H, Miyahara Y et al (2014) The factors associated with the failure of transcatheter pelvic arterial embolization for intractable postpartum hemorrhage. J Perinat Med 42:359–362CrossRefPubMed Yamasaki Y, Morita H, Miyahara Y et al (2014) The factors associated with the failure of transcatheter pelvic arterial embolization for intractable postpartum hemorrhage. J Perinat Med 42:359–362CrossRefPubMed
36.
go back to reference Descargues G, Mauger Tinlot F, Douvrin F, Clavier E, Lemoine JP, Marpeau L (2004) Menses, fertility and pregnancy after arterial embolization for the control of postpartum haemorrhage. Hum Reprod 19:339–343CrossRefPubMed Descargues G, Mauger Tinlot F, Douvrin F, Clavier E, Lemoine JP, Marpeau L (2004) Menses, fertility and pregnancy after arterial embolization for the control of postpartum haemorrhage. Hum Reprod 19:339–343CrossRefPubMed
37.
go back to reference Onwere C, Gurol-Urganci I, Cromwell DA, Mahmood TA, Templeton A, van der Meulen JH (2011) Maternal morbidity associated with placenta praevia among women who had elective caesarean section. Eur J Obstet Gynecol Reprod Biol 159:62–66CrossRefPubMed Onwere C, Gurol-Urganci I, Cromwell DA, Mahmood TA, Templeton A, van der Meulen JH (2011) Maternal morbidity associated with placenta praevia among women who had elective caesarean section. Eur J Obstet Gynecol Reprod Biol 159:62–66CrossRefPubMed
38.
go back to reference Guleria K, Gupta B, Agarwal S, Suneja A, Vaid N, Jain S (2013) Abnormally invasive placenta: changing trends in diagnosis and management. Acta Obstet Gynecol Scand 92:461–464CrossRefPubMed Guleria K, Gupta B, Agarwal S, Suneja A, Vaid N, Jain S (2013) Abnormally invasive placenta: changing trends in diagnosis and management. Acta Obstet Gynecol Scand 92:461–464CrossRefPubMed
Metadata
Title
Endovascular management of massive post-partum haemorrhage in abnormal placental implantation deliveries
Authors
Alberto Rebonato
Stefano Mosca
Matthias Fischer
Sandro Gerli
Gianluigi Orgera
Luigina Graziosi
Daniele Maiettini
Gian Carlo Di Renzo
Giorgio Epicoco
Miltiadis Krokidis
Michele Rossi
Michele Scialpi
Publication date
01-06-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-4001-z

Other articles of this Issue 6/2016

European Radiology 6/2016 Go to the issue