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European Radiology
Published in: European Radiology 6/2015

01-06-2015 | Computed Tomography

Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial

Authors: Xavier Montet, Anne-Lise Hachulla, Angeliki Neroladaki, Frederic Lador, Thierry Rochat, Diomidis Botsikas, Christoph D. Becker

Published in: European Radiology | Issue 6/2015

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Abstract

Objective

To determine whether CT pulmonary angiography (CTPA) using low mA setting reconstructed with model-based iterative reconstruction (MBIR) is equivalent to routine CTPA reconstructed with filtered back projection (FBP).

Methods

This prospective study was approved by the institutional review board and patients provided written informed consent. Eighty-two patients were examined with a low mA MBIR-CTPA (100 kV, 20 mA) and 82 patients with a standard FBP-CTPA (100 kV, 250 mA). Region of interests were drawn in nine pulmonary vessels; signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. A five-point scale was used to subjectively evaluate the image quality of FBP-CTPA and low mA MBIR-CTPA.

Results

Compared to routine FBP-CTPA, low mA MBIR-CTPA showed no differences in the attenuation measured in nine pulmonary vessels, higher SNR (56 ± 19 vs 43 ± 20, p < 0.0001) and higher CNR (50 ± 17 vs 38 ± 18, p < 0.0001) despite a dose reduction of 93 % (p < 0.0001). The subjective image quality of low mA MBIR-CTPA was quoted as diagnostic in 98 % of the cases for patient with body mass index less than 30 kg/m2.

Conclusion

Low mA MBIR-CTPA is equivalent to routine FBP-CTPA and allows a significant dose reduction while improving SNR and CNR in the pulmonary vessels, as compared with routine FBP-CTPA.

Key Points

• Low mA MBIR-CTPA is equivalent to routine FBP-CTPA.
• MBIR-CTPA may be achieved with drastic (93 %) dose reduction.
• Low mA MBIR-CTPA should be studied in the setting of suspected PE.
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Metadata
Title
Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial
Authors
Xavier Montet
Anne-Lise Hachulla
Angeliki Neroladaki
Frederic Lador
Thierry Rochat
Diomidis Botsikas
Christoph D. Becker
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3563-5

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