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European Radiology
Published in: European Radiology 3/2015

01-03-2015 | Musculoskeletal

An update on risk factors for cartilage loss in knee osteoarthritis assessed using MRI-based semiquantitative grading methods

Authors: Hamza Alizai, Frank W. Roemer, Daichi Hayashi, Michel D. Crema, David T. Felson, Ali Guermazi

Published in: European Radiology | Issue 3/2015

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Abstract

Arthroscopy-based semiquantitative scoring systems such as Outerbridge and Noyes’ scores were the first to be developed for the purpose of grading cartilage defects. As magnetic resonance imaging (MRI) became available faor evaluation of the osteoarthritic knee joint, these systems were adapted for use with MRI. Later on, grading methods such as the Whole Organ Magnetic Resonance Score, the Boston-Leeds Osteoarthritis Knee Score and the MRI Osteoarthritis Knee Score were designed specifically for performing whole-organ assessment of the knee joint structures, including cartilage. Cartilage grades on MRI obtained with these scoring systems represent optimal outcome measures for longitudinal studies, and are designed to enhance understanding of the knee osteoarthritis disease process. The purpose of this narrative review is to describe cartilage assessment in knee osteoarthritis using currently available MRI-based semiquantitative whole-organ scoring systems, and to provide an update on the risk factors for cartilage loss in knee osteoarthritis as assessed with these scoring systems.
Key Points
• Radiography is neither specific nor sensitive to progression of knee osteoarthritis
• Semiquantitative MRI-based outcome measures are useful to identify knee osteoarthritis risk factors
• Several MRI-based semiquantitative scoring systems for knee cartilage lesions are available
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Metadata
Title
An update on risk factors for cartilage loss in knee osteoarthritis assessed using MRI-based semiquantitative grading methods
Authors
Hamza Alizai
Frank W. Roemer
Daichi Hayashi
Michel D. Crema
David T. Felson
Ali Guermazi
Publication date
01-03-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 3/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3464-7

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