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Published in: European Radiology 5/2011

01-05-2011 | Cardiac

Diagnostic performance of 320-detector CT coronary angiography in patients with atrial fibrillation: preliminary results

Authors: Lei Xu, Lin Yang, Zhanming Fan, Wei Yu, Biao Lv, Zhaoqi Zhang

Published in: European Radiology | Issue 5/2011

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Abstract

Objective

To evaluate the feasibility, diagnostic accuracy, and radiation dose of CT coronary angiography (CTCA) in patients with atrial fibrillation (AF) using 320-detector CT.

Methods

Thirty-seven patients with persistent AF and suspected coronary artery disease (CAD) were enrolled. All patients underwent both 320-detector CTCA and conventional coronary angiography (CCA). CT image quality and the presence of significant (≥50%) stenosis were evaluated by two radiologists blinded to the results of CCA. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated using CCA as the reference standard. Differences in detection of coronary artery stenosis between 320-detector CTCA and CCA were evaluated with McNemar’s test. Patient radiation dose was calculated by multiplying dose length product by conversion coefficient of 0.017.

Results

In total 474 evaluated coronary segments, 459 (96.8%) segments were diagnostically evaluable. On per-segment analysis, sensitivity, specificity, PPV and NPV were 90.0% (18 of 20), 99.3% (436 of 439), 85.7% (18 of 21) and 99.5% (436 of 438). No significant difference was found between 320-detector CTCA and CCA on the detection of significant stenosis (P = 1.000). Effective doses of 320-detector CTCA was 13.0 ± 4.7 mSv.

Conclusion

320-detector CTCA is feasible and accurate in excluding CAD in patients with AF.
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Metadata
Title
Diagnostic performance of 320-detector CT coronary angiography in patients with atrial fibrillation: preliminary results
Authors
Lei Xu
Lin Yang
Zhanming Fan
Wei Yu
Biao Lv
Zhaoqi Zhang
Publication date
01-05-2011
Publisher
Springer-Verlag
Published in
European Radiology / Issue 5/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1987-0

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