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01-10-2010 | Musculoskeletal

Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation

Authors: Fabio Becce, Nicolas Theumann, Antoine Rochette, Frédérique Larousserie, Raphaël Campagna, Stéphane Cherix, Louis Guillou, Elyazid Mouhsine, Philippe Anract, Jean-Luc Drapé, Antoine Feydy

Published in: European Radiology | Issue 10/2010

Abstract

Objective:

To report the biopsy findings of osteoid osteoma (OO) and OO-mimicking lesions, assess their distinctive multidetector computed tomography (MDCT) features and evaluate treatment by radiofrequency ablation (RFA).

Methods:

In this multicentric retrospective study, 80 patients (54 male, 26 female, mean age 24.1 years, range 5–48) with presumed (clinical and MDCT features) OO were treated by percutaneous RFA between May 2002 and June 2009. Per-procedural biopsies were always performed. The following MDCT features were assessed: skeletal distribution and location within the bone, size, central calcification, surrounding osteosclerosis and periosteal reaction. Clinical success of RFA was evaluated.

Results:

Histopathological diagnoses were: 54 inconclusive biopsies, 16 OO, 10 OO-mimicking lesions (5 chronic osteomyelitis, 3 chondroblastoma, 1 eosinophilic granuloma, 1 fibrous dysplasia). OO-mimicking lesions were significantly greater in size (p = 0.001) and presented non-significant trends towards medullary location (p = 0.246), moderate surrounding osteosclerosis (p = 0.189) and less periosteal reaction (p = 0.197), compared with OO. Primary success for ablation of OO-mimicking lesions was 100% at 1 month, 85.7% at 6 and 12 months, and 66.7% at 24 months. Secondary success was 100%.

Conclusion:

Larger size, medullary location, less surrounding osteosclerosis and periosteal reaction on MDCT may help differentiate OO-mimicking lesions from OO. OO-mimicking lesions are safely and successfully treated by RFA.

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Title: Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation
Authors: Fabio Becce
Nicolas Theumann
Antoine Rochette
Frédérique Larousserie
Raphaël Campagna
Stéphane Cherix
Louis Guillou
Elyazid Mouhsine
Philippe Anract
Jean-Luc Drapé
Antoine Feydy
Publication date: 01-10-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 10/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1811-x

At a glance: The STEP trials

Springer Medicine

Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation

Abstract

Objective:

Methods:

Results:

Conclusion:

At a glance: The STEP trials

Springer Medicine

Abstract

Objective:

Methods:

Results:

Conclusion:

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