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Open Access 01-09-2010 | Breast

Consequences of digital mammography in population-based breast cancer screening: initial changes and long-term impact on referral rates

Authors: Adriana M. J. Bluekens, Nico Karssemeijer, David Beijerinck, Jan J. M. Deurenberg, Ruben E. van Engen, Mireille J. M. Broeders, Gerard J. den Heeten

Published in: European Radiology | Issue 9/2010

Abstract

Objectives:

To investigate the referral pattern after the transition to full-field digital mammography (FFDM) in a population-based breast cancer screening programme.

Methods:

Preceding the nationwide digitalisation of the Dutch screening programme, an FFDM feasibility study was conducted. Detection and referral rates for FFDM and screen-film mammography (SFM) were compared for first and subsequent screens. Furthermore, radiological characteristics of referrals in digital screening were assessed.

Results:

A total of 312,414 screening mammograms were performed (43,913 digital and 268,501 conventional), with 4,473 consecutive referrals (966 following FFDM). Initially the FFDM referral rate peaked, and many false-positive results were noted as a consequence of pseudolesions and increased detection of (benign) microcalcifications. A higher overall referral rate was observed in FFDM screening in both first and subsequent examinations (p < .001), with a significant increase in cancer detection (p = .010).

Conclusion:

As a result of initial inexperience with digital screening images implementing FFDM in a population-based breast cancer screening programme may lead to a strong, but temporary increase in referral. Dedicated training in digital screening for radiographers and screening radiologists is therefore recommended. Referral rates decrease and stabilise (learning curve effect) at a higher level than in conventional screening, yet with significantly enhanced cancer detection.

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Title: Consequences of digital mammography in population-based breast cancer screening: initial changes and long-term impact on referral rates
Authors: Adriana M. J. Bluekens
Nico Karssemeijer
David Beijerinck
Jan J. M. Deurenberg
Ruben E. van Engen
Mireille J. M. Broeders
Gerard J. den Heeten
Publication date: 01-09-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 9/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1786-7

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Consequences of digital mammography in population-based breast cancer screening: initial changes and long-term impact on referral rates

Abstract

Objectives:

Methods:

Results:

Conclusion:

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objectives:

Methods:

Results:

Conclusion:

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