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Published in: European Radiology 1/2009

01-01-2009 | Vascular-Interventional

Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b

Authors: Tim F. Weber, Maria-Katharina Ganten, Dittmar Böckler, Philipp Geisbüsch, Annette Kopp-Schneider, Hans-Ulrich Kauczor, Hendrik von Tengg-Kobligk

Published in: European Radiology | Issue 1/2009

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Abstract

To characterize the heartbeat-related distension of dissected and non-dissected thoracic aortic segments in chronic aortic dissection type b (CADB) ECG-gated computed tomography angiography was performed in ten CADB patients. For 20 time points of the R–R interval, multiplanar reformations were taken at non-dissected (A, B) and dissected (C) aorta: ascending aorta (A), aortic vertex (B), 10 cm distal to left subclavian (Ct, true channel; Cf, false channel). Relative amplitudes of aortic area and major and minor axis diameter changes were quantified. Area amplitudes were 12.9 ± 3.7%, 11.4 ± 1.8%, 16.5 ± 5.9% and 10.5 ± 5.7% at A, B, Ct and Cf, respectively. Area amplitudes were significantly greater at Ct than at Cf and B (p < 0.05). Major axis diameter amplitudes were 7.7 ± 1.9%, 6.2 ± 1.3%, 5.9 ± 2.0% and 6.1 ± 3.6% at A, B, Ct and Cf, respectively. There were no differences in major axis diameter amplitudes. Minor axis diameter amplitudes were 6.7 ± 2.1%, 8.4 ± 1.9%, 12.7 ± 6.3% and 6.0 ± 2.2% at A, B, Ct and Cf, respectively. Minor axis diameter amplitudes were significantly the greatest at Ct (p < 0.05). In CADB, the heartbeat-related distension of aortic area and diameter is evenly distributed over the non-dissected aortic arch. As a result from different blood flow properties, there are significantly greater conformational changes in the true channel of the dissected aorta.
Literature
1.
go back to reference Meszaros I, Morocz J, Szlavi J et al (2000) Epidemiology and clinicopathology of aortic dissection. Chest 117:1271–1278PubMedCrossRef Meszaros I, Morocz J, Szlavi J et al (2000) Epidemiology and clinicopathology of aortic dissection. Chest 117:1271–1278PubMedCrossRef
2.
go back to reference Gleason TG (2005) Heritable disorders predisposing to aortic dissection. Semin Thorac Cardiovasc Surg 17:274–281PubMedCrossRef Gleason TG (2005) Heritable disorders predisposing to aortic dissection. Semin Thorac Cardiovasc Surg 17:274–281PubMedCrossRef
3.
go back to reference Shennan T (1934) Dissecting aneurysms special report. Medical Research Council, London Shennan T (1934) Dissecting aneurysms special report. Medical Research Council, London
4.
go back to reference Spittell PC, Spittell JA Jr, Joyce JW et al (1993) Clinical features and differential diagnosis of aortic dissection: experience with 236 cases (1980 through 1990). Mayo Clin Proc 68:642–651PubMed Spittell PC, Spittell JA Jr, Joyce JW et al (1993) Clinical features and differential diagnosis of aortic dissection: experience with 236 cases (1980 through 1990). Mayo Clin Proc 68:642–651PubMed
5.
go back to reference Coselli JS, de Figueiredo LF (1997) Natural history of descending and thoracoabdominal aortic aneurysms. J Card Surg 12:285–289 discussion 289–291PubMed Coselli JS, de Figueiredo LF (1997) Natural history of descending and thoracoabdominal aortic aneurysms. J Card Surg 12:285–289 discussion 289–291PubMed
6.
go back to reference Hagan PG, Nienaber CA, Isselbacher EM et al (2000) The international registry of acute aortic dissection (IRAD): new insights into an old disease. JAMA 283:897–903PubMedCrossRef Hagan PG, Nienaber CA, Isselbacher EM et al (2000) The international registry of acute aortic dissection (IRAD): new insights into an old disease. JAMA 283:897–903PubMedCrossRef
7.
go back to reference McGee EC Jr, Pham DT, Gleason TG (2005) Chronic descending aortic dissections. Semin Thorac Cardiovasc Surg 17:262–267PubMedCrossRef McGee EC Jr, Pham DT, Gleason TG (2005) Chronic descending aortic dissections. Semin Thorac Cardiovasc Surg 17:262–267PubMedCrossRef
8.
go back to reference Ince H, Nienaber CA (2007) Etiology, pathogenesis and management of thoracic aortic aneurysm. Nat Clin Pract Cardiovasc Med 4:418–427PubMedCrossRef Ince H, Nienaber CA (2007) Etiology, pathogenesis and management of thoracic aortic aneurysm. Nat Clin Pract Cardiovasc Med 4:418–427PubMedCrossRef
9.
go back to reference Schumacher H, Böckler D, Allenberg JR (2004) Surgical management of thoracic aortic lesions. Aneurysm, dissection and traumatic rupture. Chirurg 75:937–958PubMedCrossRef Schumacher H, Böckler D, Allenberg JR (2004) Surgical management of thoracic aortic lesions. Aneurysm, dissection and traumatic rupture. Chirurg 75:937–958PubMedCrossRef
10.
go back to reference Winnerkvist A, Lockowandt U, Rasmussen E et al (2006) A prospective study of medically treated acute type B aortic dissection. Eur J Vasc Endovasc Surg 32:349–355PubMedCrossRef Winnerkvist A, Lockowandt U, Rasmussen E et al (2006) A prospective study of medically treated acute type B aortic dissection. Eur J Vasc Endovasc Surg 32:349–355PubMedCrossRef
11.
go back to reference Czermak BV, Waldenberger P, Fraedrich G et al (2000) Treatment of Stanford type B aortic dissection with stent-grafts: preliminary results. Radiology 217:544–550PubMed Czermak BV, Waldenberger P, Fraedrich G et al (2000) Treatment of Stanford type B aortic dissection with stent-grafts: preliminary results. Radiology 217:544–550PubMed
12.
go back to reference Lopera J, Patino JH, Urbina C et al (2003) Endovascular treatment of complicated type-B aortic dissection with stent-grafts: midterm results. J Vasc Interv Radiol 14:195–203PubMed Lopera J, Patino JH, Urbina C et al (2003) Endovascular treatment of complicated type-B aortic dissection with stent-grafts: midterm results. J Vasc Interv Radiol 14:195–203PubMed
13.
go back to reference Riesenman PJ, Farber MA, Mendes RR et al (2005) Endovascular repair of lesions involving the descending thoracic aorta. J Vasc Surg 42:1063–1074PubMedCrossRef Riesenman PJ, Farber MA, Mendes RR et al (2005) Endovascular repair of lesions involving the descending thoracic aorta. J Vasc Surg 42:1063–1074PubMedCrossRef
14.
go back to reference Stone DH, Brewster DC, Kwolek CJ et al (2006) Stent-graft versus open-surgical repair of the thoracic aorta: mid-term results. J Vasc Surg 44:1188–1197PubMedCrossRef Stone DH, Brewster DC, Kwolek CJ et al (2006) Stent-graft versus open-surgical repair of the thoracic aorta: mid-term results. J Vasc Surg 44:1188–1197PubMedCrossRef
15.
go back to reference Böckler D, Schumacher H, Ganten M et al (2006) Complications after endovascular repair of acute symptomatic and chronic expanding Stanford type B aortic dissections. J Thorac Cardiovasc Surg 132:361–368PubMedCrossRef Böckler D, Schumacher H, Ganten M et al (2006) Complications after endovascular repair of acute symptomatic and chronic expanding Stanford type B aortic dissections. J Thorac Cardiovasc Surg 132:361–368PubMedCrossRef
16.
go back to reference Thurnher SA, Grabenwoger M (2002) Endovascular treatment of thoracic aortic aneurysms: a review. Eur Radiol 12:1370–1387PubMedCrossRef Thurnher SA, Grabenwoger M (2002) Endovascular treatment of thoracic aortic aneurysms: a review. Eur Radiol 12:1370–1387PubMedCrossRef
17.
go back to reference Fattori R, Napoli G, Lovato L et al (2003) Descending thoracic aortic diseases: stent-graft repair. Radiology 229:176–183PubMedCrossRef Fattori R, Napoli G, Lovato L et al (2003) Descending thoracic aortic diseases: stent-graft repair. Radiology 229:176–183PubMedCrossRef
18.
go back to reference Di Tommaso L, Monaco M, Mottola M et al (2006) Major complications following endovascular surgery of descending thoracic aorta. Interact Cardiovasc Thorac Surg 5:705–708PubMedCrossRef Di Tommaso L, Monaco M, Mottola M et al (2006) Major complications following endovascular surgery of descending thoracic aorta. Interact Cardiovasc Thorac Surg 5:705–708PubMedCrossRef
19.
go back to reference Nienaber CA, Kische S, Ince H (2007) Thoracic aortic stent-graft devices: problems, failure modes, and applicability. Semin Vasc Surg 20:81–89PubMedCrossRef Nienaber CA, Kische S, Ince H (2007) Thoracic aortic stent-graft devices: problems, failure modes, and applicability. Semin Vasc Surg 20:81–89PubMedCrossRef
20.
go back to reference Weigel S, Tombach B, Maintz D et al (2003) Thoracic aortic stent graft: comparison of contrast-enhanced MR angiography and CT angiography in the follow-up: initial results. Eur Radiol 13:1628–1634PubMedCrossRef Weigel S, Tombach B, Maintz D et al (2003) Thoracic aortic stent graft: comparison of contrast-enhanced MR angiography and CT angiography in the follow-up: initial results. Eur Radiol 13:1628–1634PubMedCrossRef
21.
go back to reference Willoteaux S, Lions C, Gaxotte V et al (2004) Imaging of aortic dissection by helical computed tomography (CT). Eur Radiol 14:1999–2008PubMedCrossRef Willoteaux S, Lions C, Gaxotte V et al (2004) Imaging of aortic dissection by helical computed tomography (CT). Eur Radiol 14:1999–2008PubMedCrossRef
22.
go back to reference Böckler D, Hylik-Dürr A, von Tengg-Kobligk H et al (2007) Clinical requirements of aortic imaging. Radiologe 47:962–973PubMedCrossRef Böckler D, Hylik-Dürr A, von Tengg-Kobligk H et al (2007) Clinical requirements of aortic imaging. Radiologe 47:962–973PubMedCrossRef
23.
go back to reference Huber A, Matzko M, Wintersperger BJ et al (2001) Reconstruction methods in postprocessing of CT- and MR-angiography of the aorta. Radiologe 41:689–694PubMedCrossRef Huber A, Matzko M, Wintersperger BJ et al (2001) Reconstruction methods in postprocessing of CT- and MR-angiography of the aorta. Radiologe 41:689–694PubMedCrossRef
24.
go back to reference Parker MV, O’Donnell SD, Chang AS et al (2005) What imaging studies are necessary for abdominal aortic endograft sizing? A prospective blinded study using conventional computed tomography, aortography, and three-dimensional computed tomography. J Vasc Surg 41:199–205PubMedCrossRef Parker MV, O’Donnell SD, Chang AS et al (2005) What imaging studies are necessary for abdominal aortic endograft sizing? A prospective blinded study using conventional computed tomography, aortography, and three-dimensional computed tomography. J Vasc Surg 41:199–205PubMedCrossRef
25.
go back to reference Ganten M, Boese JM, Leitermann D et al (2005) Quantification of aortic elasticity: development and experimental validation of a method using computed tomography. Eur Radiol 15:2506–2512PubMedCrossRef Ganten M, Boese JM, Leitermann D et al (2005) Quantification of aortic elasticity: development and experimental validation of a method using computed tomography. Eur Radiol 15:2506–2512PubMedCrossRef
26.
go back to reference Ganten M, Krautter U, Hosch W et al (2007) Age related changes of human aortic distensibility: evaluation with ECG-gated CT. Eur Radiol 17:701–708PubMedCrossRef Ganten M, Krautter U, Hosch W et al (2007) Age related changes of human aortic distensibility: evaluation with ECG-gated CT. Eur Radiol 17:701–708PubMedCrossRef
27.
go back to reference Ganten M, von Tengg-Kobligk H, Weber TF et al (2008) Charakterisierung der Membranbewegung bei Patienten mit chronischer B-Dissektion mittels EKG-getriggerter CT. Rofo 180:S157 Ganten M, von Tengg-Kobligk H, Weber TF et al (2008) Charakterisierung der Membranbewegung bei Patienten mit chronischer B-Dissektion mittels EKG-getriggerter CT. Rofo 180:S157
28.
go back to reference Muhs BE, Vincken KL, van Prehn J et al (2006) Dynamic cine-CT angiography for the evaluation of the thoracic aorta; insight in dynamic changes with implications for thoracic endograft treatment. Eur J Vasc Endovasc Surg 32:532–536PubMedCrossRef Muhs BE, Vincken KL, van Prehn J et al (2006) Dynamic cine-CT angiography for the evaluation of the thoracic aorta; insight in dynamic changes with implications for thoracic endograft treatment. Eur J Vasc Endovasc Surg 32:532–536PubMedCrossRef
29.
go back to reference van Prehn J, Vincken KL, Muhs BE et al (2007) Toward endografting of the ascending aorta: insight into dynamics using dynamic cine-CTA. J Endovasc Ther 14:551–560PubMedCrossRef van Prehn J, Vincken KL, Muhs BE et al (2007) Toward endografting of the ascending aorta: insight into dynamics using dynamic cine-CTA. J Endovasc Ther 14:551–560PubMedCrossRef
30.
go back to reference Herold U, Piotrowski J, Baumgart D et al (2002) Endoluminal stent graft repair for acute and chronic type B aortic dissection and atherosclerotic aneurysm of the thoracic aorta: an interdisciplinary task. Eur J Cardiothorac Surg 22:891–897PubMedCrossRef Herold U, Piotrowski J, Baumgart D et al (2002) Endoluminal stent graft repair for acute and chronic type B aortic dissection and atherosclerotic aneurysm of the thoracic aorta: an interdisciplinary task. Eur J Cardiothorac Surg 22:891–897PubMedCrossRef
31.
go back to reference Sternbergh WC 3rd, Money SR, Greenberg RK et al (2004) Influence of endograft oversizing on device migration, endoleak, aneurysm shrinkage, and aortic neck dilation: results from the Zenith Multicenter Trial. J Vasc Surg 39:20–26PubMedCrossRef Sternbergh WC 3rd, Money SR, Greenberg RK et al (2004) Influence of endograft oversizing on device migration, endoleak, aneurysm shrinkage, and aortic neck dilation: results from the Zenith Multicenter Trial. J Vasc Surg 39:20–26PubMedCrossRef
32.
go back to reference Mohan IV, Laheij RJ, Harris PL (2001) Risk factors for endoleak and the evidence for stent-graft oversizing in patients undergoing endovascular aneurysm repair. Eur J Vasc Endovasc Surg 21:344–349PubMedCrossRef Mohan IV, Laheij RJ, Harris PL (2001) Risk factors for endoleak and the evidence for stent-graft oversizing in patients undergoing endovascular aneurysm repair. Eur J Vasc Endovasc Surg 21:344–349PubMedCrossRef
33.
go back to reference Shimono T, Kato N, Yasuda F et al (2002) Transluminal stent-graft placements for the treatments of acute onset and chronic aortic dissections. Circulation 106:I241–247PubMed Shimono T, Kato N, Yasuda F et al (2002) Transluminal stent-graft placements for the treatments of acute onset and chronic aortic dissections. Circulation 106:I241–247PubMed
34.
go back to reference Schumacher H, Von Tengg-Kobligk H, Ostovic M et al (2006) Hybrid aortic procedures for endoluminal arch replacement in thoracic aneurysms and type B dissections. J Cardiovasc Surg (Torino) 47:509–517 Schumacher H, Von Tengg-Kobligk H, Ostovic M et al (2006) Hybrid aortic procedures for endoluminal arch replacement in thoracic aneurysms and type B dissections. J Cardiovasc Surg (Torino) 47:509–517
35.
go back to reference Chang JM, Friese K, Caputo GR et al (1991) MR measurement of blood flow in the true and false channel in chronic aortic dissection. J Comput Assist Tomogr 15:418–423PubMedCrossRef Chang JM, Friese K, Caputo GR et al (1991) MR measurement of blood flow in the true and false channel in chronic aortic dissection. J Comput Assist Tomogr 15:418–423PubMedCrossRef
36.
go back to reference Inoue T, Watanabe S, Sakurada H et al (2000) Evaluation of flow volume and flow patterns in the patent false lumen of chronic aortic dissections using velocity-encoded cine magnetic resonance imaging. Jpn Circ J 64:760–764PubMedCrossRef Inoue T, Watanabe S, Sakurada H et al (2000) Evaluation of flow volume and flow patterns in the patent false lumen of chronic aortic dissections using velocity-encoded cine magnetic resonance imaging. Jpn Circ J 64:760–764PubMedCrossRef
37.
go back to reference Markl M, Draney MT, Hope MD et al (2004) Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J Comput Assist Tomogr 28:459–468PubMedCrossRef Markl M, Draney MT, Hope MD et al (2004) Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J Comput Assist Tomogr 28:459–468PubMedCrossRef
38.
go back to reference Xu SD, Huang FJ, Du JH et al (2008) A study of aortic dimension in type B aortic dissection. Interact Cardiovasc Thorac Surg 7(2):244–8 Epub 2008 Jan 10PubMedCrossRef Xu SD, Huang FJ, Du JH et al (2008) A study of aortic dimension in type B aortic dissection. Interact Cardiovasc Thorac Surg 7(2):244–8 Epub 2008 Jan 10PubMedCrossRef
39.
go back to reference Kortesniemi M, Kiljunen T, Kangasmaki A (2006) Radiation exposure in body computed tomography examinations of trauma patients. Phys Med Biol 51:3269–3282PubMedCrossRef Kortesniemi M, Kiljunen T, Kangasmaki A (2006) Radiation exposure in body computed tomography examinations of trauma patients. Phys Med Biol 51:3269–3282PubMedCrossRef
40.
go back to reference Gray JE, Archer BR, Butler PF et al (2005) Reference values for diagnostic radiology: application and impact. Radiology 235:354–358PubMedCrossRef Gray JE, Archer BR, Butler PF et al (2005) Reference values for diagnostic radiology: application and impact. Radiology 235:354–358PubMedCrossRef
41.
go back to reference Duvernoy O, Coulden R, Ytterberg C (1995) Aortic motion: a potential pitfall in CT imaging of dissection in the ascending aorta. J Comput Assist Tomogr 19:569–572PubMedCrossRef Duvernoy O, Coulden R, Ytterberg C (1995) Aortic motion: a potential pitfall in CT imaging of dissection in the ascending aorta. J Comput Assist Tomogr 19:569–572PubMedCrossRef
42.
go back to reference Beller CJ, Labrosse MR, Thubrikar MJ et al (2004) Role of aortic root motion in the pathogenesis of aortic dissection. Circulation 109:763–769PubMedCrossRef Beller CJ, Labrosse MR, Thubrikar MJ et al (2004) Role of aortic root motion in the pathogenesis of aortic dissection. Circulation 109:763–769PubMedCrossRef
Metadata
Title
Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b
Authors
Tim F. Weber
Maria-Katharina Ganten
Dittmar Böckler
Philipp Geisbüsch
Annette Kopp-Schneider
Hans-Ulrich Kauczor
Hendrik von Tengg-Kobligk
Publication date
01-01-2009
Publisher
Springer-Verlag
Published in
European Radiology / Issue 1/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-008-1103-x

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