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01-11-2008 | Cardiac Imaging

Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience

Authors: Balazs Ruzsics, Heon Lee, Peter L. Zwerner, Mulugeta Gebregziabher, Philip Costello, U. Joseph Schoepf

Published in: European Radiology | Issue 11/2008

Abstract

We aimed to evaluate the feasibility of diagnosing coronary stenosis and myocardial ischemia with a single dual-energy CT (DECT) acquisition. Thirty-five patients underwent contrast-enhanced, ECG-gated DECT of the heart while independently operating the two tubes of a dual-source CT system at high- and low-energy X-ray spectra. From the same raw data, coronary CTA (cCTA) studies were reconstructed for stenosis detection, and the myocardial blood-pool was analyzed by determining the tissue iodine content. Two independent observers analyzed all studies for stenosis and myocardial blood-pool deficits. Results were correlated with SPECT, coronary catheterization and cCTA on a segmental basis. cCTA had 98% sensitivity, 88% specificity and 92% accuracy for detection of >50% stenosis. DECT detected myocardial ischemia with 84% sensitivity, 94% specificity and 92% accuracy. Our initial experience may warrant further exploration of DECT as a possibly feasible single imaging investigation for the comprehensive diagnosis of coronary stenosis and myocardial ischemia.

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Title: Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience
Authors: Balazs Ruzsics
Heon Lee
Peter L. Zwerner
Mulugeta Gebregziabher
Philip Costello
U. Joseph Schoepf
Publication date: 01-11-2008
Publisher: Springer-Verlag
Published in: European Radiology / Issue 11/2008
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-008-1022-x

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Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience

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