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Rheumatology International
Published in: Rheumatology International 5/2015

01-05-2015 | Review Article - Therapy Review

Potentially effective natural drugs in treatment for the most common rheumatic disorder: osteoarthritis

Authors: Mohammad Hosein Farzaei, Fatemeh Farzaei, Maziar Gooshe, Zahra Abbasabadi, Nima Rezaei, Amir Hossein Abdolghaffari

Published in: Rheumatology International | Issue 5/2015

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Abstract

Osteoarthritis (OA) is a chronic condition in which imbalance between anabolic and catabolic mediators occurs leading to the destruction of homeostasis of articular cartilage. The current drugs in the management of OA can just alleviate symptoms. Hence, the research tendency toward exploration of novel sources has been grown up in order to achieve safe and efficacious drugs. Meanwhile, various components exist as novel natural drugs that may possess favorable properties for the management of OA. This review focuses on the most efficacious medicinal plants and their phytochemical agents, which have been consumed for the management of OA. Moreover, evaluation of their efficacy and molecular mechanisms of action are discussed based on numerous modern experimental investigations. More research is needed to develop therapeutic agents with disease-modifying properties to treat OA.
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Metadata
Title
Potentially effective natural drugs in treatment for the most common rheumatic disorder: osteoarthritis
Authors
Mohammad Hosein Farzaei
Fatemeh Farzaei
Maziar Gooshe
Zahra Abbasabadi
Nima Rezaei
Amir Hossein Abdolghaffari
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Rheumatology International / Issue 5/2015
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-014-3175-z

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