Skip to main content
Top
Published in: Rheumatology International 3/2012

01-03-2012 | Short Communication

A case of primary Sjögren’s syndrome presenting primarily with central nervous system vasculitic involvement

Authors: Zehra Isik Hasiloglu, Sait Albayram, Koray Tasmali, Burak Erer, Hakan Selcuk, Civan Islak

Published in: Rheumatology International | Issue 3/2012

Login to get access

Abstract

Sjögren’s syndrome is primarily a chronic systemic autoimmune disease that affects exocrine organs. Neurologic symptoms frequently present as peripheral neuropathy due to small vessel vasculitis. Type and prevalence of central nervous system involvement are still controversial. In this report, we present a 35-year-old woman with primary Sjögren’s syndrome with central nervous system vasculitic involvement.
Literature
1.
go back to reference Garcia-Carrasco M, Ramos-Casals M, Rosas J et al (2002) Primary Sjogren syndrome: clinical and immunologic disease patterns in a cohort of 400 patients. Medicine 81:270–280PubMedCrossRef Garcia-Carrasco M, Ramos-Casals M, Rosas J et al (2002) Primary Sjogren syndrome: clinical and immunologic disease patterns in a cohort of 400 patients. Medicine 81:270–280PubMedCrossRef
2.
go back to reference Morgen K, McFarland HF, Pillemer SR (2004) Central nervous system disease in primary Sjögren syndrome: the role of magnetic resonance imaging. Semin Arthritis Rheum 34:623–630PubMedCrossRef Morgen K, McFarland HF, Pillemer SR (2004) Central nervous system disease in primary Sjögren syndrome: the role of magnetic resonance imaging. Semin Arthritis Rheum 34:623–630PubMedCrossRef
3.
go back to reference Sanahuja J, Ordon˜ ez-Palau S, Begué R, Brieva L, Boquet D (2008) Primary Sjögren syndrome with tumefactive central nervous system involvement. AJNR Am J Neuroradiol 29:1878–1879PubMedCrossRef Sanahuja J, Ordon˜ ez-Palau S, Begué R, Brieva L, Boquet D (2008) Primary Sjögren syndrome with tumefactive central nervous system involvement. AJNR Am J Neuroradiol 29:1878–1879PubMedCrossRef
4.
go back to reference Sjögren H (1935) Zur kenntnis der keratoconjunctivitis sicca: allgemeine symtomatologie und aetiologie. Acta Ophthalmol 57:983–996 Sjögren H (1935) Zur kenntnis der keratoconjunctivitis sicca: allgemeine symtomatologie und aetiologie. Acta Ophthalmol 57:983–996
5.
go back to reference Delalande S, de Seze J, Fauchais AL et al (2004) Neurologic manifestations in primary Sjögren syndrome: a study of 82 patients. Medicine 83:280–291PubMedCrossRef Delalande S, de Seze J, Fauchais AL et al (2004) Neurologic manifestations in primary Sjögren syndrome: a study of 82 patients. Medicine 83:280–291PubMedCrossRef
6.
go back to reference Shearn M (1971) Sjögren’s syndrome. WB Saunders, Philadelphia Shearn M (1971) Sjögren’s syndrome. WB Saunders, Philadelphia
7.
go back to reference Talal N, Sokoloff L, Barth WF (1967) Extrasalivary lymphoid abnormalities in Sjögren’s syndrome (reticulum cell sarcoma, pseudolymphoma, macroglobulinemia). Am J Med 43:50–65PubMedCrossRef Talal N, Sokoloff L, Barth WF (1967) Extrasalivary lymphoid abnormalities in Sjögren’s syndrome (reticulum cell sarcoma, pseudolymphoma, macroglobulinemia). Am J Med 43:50–65PubMedCrossRef
8.
go back to reference Alexander EL, Ranzenbach MR, Kumar AJ, Kozachuk WE, Rosenbaum AE, Patronas N et al (1994) Anti-Ro(SS-A) autoantibodies in central nervous system disease associated with Sjogren’s syndrome (CNS-SS): clinical, neuroimaging, and angiographic correlates. Neurology 44:899–908PubMed Alexander EL, Ranzenbach MR, Kumar AJ, Kozachuk WE, Rosenbaum AE, Patronas N et al (1994) Anti-Ro(SS-A) autoantibodies in central nervous system disease associated with Sjogren’s syndrome (CNS-SS): clinical, neuroimaging, and angiographic correlates. Neurology 44:899–908PubMed
9.
go back to reference Alexander EL, Craft C, Dorsch C, Moser RL, Provost TT, Alexander GE (1982) Necrotizing arteritis and spinal subarachnoid hemorrhage in Sjögren’s syndrome. Ann Neurol 11:632–635PubMedCrossRef Alexander EL, Craft C, Dorsch C, Moser RL, Provost TT, Alexander GE (1982) Necrotizing arteritis and spinal subarachnoid hemorrhage in Sjögren’s syndrome. Ann Neurol 11:632–635PubMedCrossRef
10.
go back to reference Alexander EL, Provost TT, Stevens MB, Alexander GE (1982) Neurologic complications of primary Sjögren’s syndrome. Medicine 61:247–257PubMedCrossRef Alexander EL, Provost TT, Stevens MB, Alexander GE (1982) Neurologic complications of primary Sjögren’s syndrome. Medicine 61:247–257PubMedCrossRef
11.
go back to reference Alexander EL (1986) Central nervous system (CNS) manifestations of primary Sjögren’s syndrome: an overview. Scand J Rheumatol Suppl 61:161–165PubMed Alexander EL (1986) Central nervous system (CNS) manifestations of primary Sjögren’s syndrome: an overview. Scand J Rheumatol Suppl 61:161–165PubMed
12.
go back to reference Alexander EL (1993) Neurologic disease in Sjögren’s syndrome: a mononuclear inflammatory vasculopathy affecting central/peripheral nervous system and muscle. A clinical review and update of immunopathogenesis. Rheum Dis Clin North Am 19:869–908PubMed Alexander EL (1993) Neurologic disease in Sjögren’s syndrome: a mononuclear inflammatory vasculopathy affecting central/peripheral nervous system and muscle. A clinical review and update of immunopathogenesis. Rheum Dis Clin North Am 19:869–908PubMed
13.
go back to reference Molina R, Provost TT, Alexander EL (1985) Peripheral inflammatory vascular disease in Sjögren’s syndrome. Association with nervous system complications. Arthritis Rheum 28:1341–1347PubMedCrossRef Molina R, Provost TT, Alexander EL (1985) Peripheral inflammatory vascular disease in Sjögren’s syndrome. Association with nervous system complications. Arthritis Rheum 28:1341–1347PubMedCrossRef
14.
go back to reference Ferreiro JE, Robalino BD, Saldana MJ (1987) Primary Sjögren’s syndrome with diffuse cerebral vasculitis and lymphocytic interstitial pneumonitis. Am J Med 82:1227–1232PubMedCrossRef Ferreiro JE, Robalino BD, Saldana MJ (1987) Primary Sjögren’s syndrome with diffuse cerebral vasculitis and lymphocytic interstitial pneumonitis. Am J Med 82:1227–1232PubMedCrossRef
Metadata
Title
A case of primary Sjögren’s syndrome presenting primarily with central nervous system vasculitic involvement
Authors
Zehra Isik Hasiloglu
Sait Albayram
Koray Tasmali
Burak Erer
Hakan Selcuk
Civan Islak
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 3/2012
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-011-1824-z

Other articles of this Issue 3/2012

Rheumatology International 3/2012 Go to the issue