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Rheumatology International
Published in: Rheumatology International 1/2013

01-01-2013 | Case Report

Immune complex reaction after successful treatment of meningococcal disease: an excellent response to IVIG

Authors: Rashna Dass, Himesh Barman, Saurabh Gohain Duwarah, Nayan Mani Deka, Pankaj Jain, Vivek Choudhury

Published in: Rheumatology International | Issue 1/2013

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Abstract

The convalescence phase of severe meningococcal sepsis is complicated by immune complex reactions with arthritis being the commonest. No standard guidelines exist for management of such complications, but non-steroidal anti-inflammatory drugs and steroids have been used with varying success. We report excellent response to intravenous immunoglobulin in a child with immune complex reaction following meningococcal sepsis.
Literature
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Anderson MS, Glade MP, Smith AL Meningococcal disease. In: Feigin, Cherry, Demmer, Kaplan (eds) Textbook of pediatric infections diseases, 5th edn. Saunders, Philadelphia, 1256–1277
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Whittle HC, Abdullahi MT, Fakunle FA et al (1973) Allergic complications of meningococcal disease. I. Clinical aspects. Br Med J 2(5869):733–737PubMedCrossRef
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Greenwood BM, Whittle HC, Byrceson AD (1973) Allergic complications of meningococcal disease. II. Immunologic investigations. Br Med J 2(5869):737–740PubMedCrossRef
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Goedvolk CA, von Rosenstiel IA, Bos AP (2003) Immune complex associated complications in the subacute phase of meningococcal disease: incidence and literature review. Arch Dis Child 88(10):927–930PubMedCrossRef
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Keeling PW, Aston NO, Croft DN (1980) Steroid-responsive vasculitis and arthritis in meningococcal septicaemia. Postgrad Med J 56(661):800–801PubMedCrossRef
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Tosila MN, Fretzayas A, Georgouli H et al (2004) Invasive meningococcal disease presenting as Henoch- Schonlein purpura. Eur J Clin Microbiol Infect Dis 23(10):776–779CrossRef
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Metadata
Title
Immune complex reaction after successful treatment of meningococcal disease: an excellent response to IVIG
Authors
Rashna Dass
Himesh Barman
Saurabh Gohain Duwarah
Nayan Mani Deka
Pankaj Jain
Vivek Choudhury
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 1/2013
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1555-6

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