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Rheumatology International
Published in: Rheumatology International 2/2011

01-02-2011 | Review

Pathophysiology and antioxidant status of patients with fibromyalgia

Authors: Riffat Iqbal, M. S. Mughal, Najma Arshad, Muhammad Arshad

Published in: Rheumatology International | Issue 2/2011

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Abstract

Fibromyalgia syndrome (FMS) is characterized by systemic pain of unknown etiology and is often accompanied by various psychological symptoms. Research on different parameters in fibromyalgia (FM) indicates that multifactors are involved in its pathophysiology; such as genetic factors, substance P, serotonin, hypothalamic pituitary adrenal axis (HPA), muscles metabolic dysfunction, reactive oxygen species (ROS) and reactive nitrogen species (RNS). Oxidative stress has also been implicated in the pathophysiology of FM; therefore, supplementation with antioxidants may be important in modulation of the effects of ROS in patients with FM.
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Metadata
Title
Pathophysiology and antioxidant status of patients with fibromyalgia
Authors
Riffat Iqbal
M. S. Mughal
Najma Arshad
Muhammad Arshad
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 2/2011
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1470-x

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