Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

ACC 2024 Congress

Catch up on all the top stories and latest evidence in cardiology research with our ACC 2024 Congress hub page.
ADVANCED SEARCH
Log in
Top
Rheumatology International
Published in: Rheumatology International 7/2012

01-07-2012 | Case Report

A case of Degos disease successfully treated with corticosteroid combined with cyclophosphamide

Authors: Tomohiro Kameda, Hiroaki Dobashi, Kozo Yoneda, Kentaro Susaki, Toshiya Kuno, Koji Murao, Toshihiko Ishida

Published in: Rheumatology International | Issue 7/2012

Login to get access

Abstract

Degos disease is a rare disorder characterized by systemic vasculitis involving various organs. There is no established, effective treatment for the disorder, and its prognosis is still poor. Combination therapy with corticosteroid and cyclophosphamide is considered effective for vasculitides involving the small arteries such as ANCA-associated vasculitis. We present here a 42-year-old man who developed Degos disease over several months, and was successfully treated using combined treatment with corticosteroid and cyclophosphamide.
Literature
1.
2.
3.
McFarkand HR (1978) Papulosis atrophicans maligna (Kohlmeier-Degos disease): a disseminated occlusive vasculopathy. Ann Neurol 3:388–392CrossRef
4.
Fauci AS, Haynes BF, Katz P, Wolff SM (1983) Wegener’s granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 98:76–85PubMed
5.
Yazici Y (2008) Systemic vasculitis treatment and monitoring update, 2008. Bull NYU Hosp Jt Dis 66(3):228–230PubMed
6.
Lapraik C, Watts R, Bacon P, Carruthers D, Chakravarty K et al (2007) BSR and BHPR guidelines for the management of adult with ANCA associated vasculitis. Rheumatology (Oxford) 46(10):1615–1616CrossRef
7.
Kohlmeier W (1941) Multiple Hautnekrosen bei Trombangitis obliterans. Arch Klin Exp Dermatol 181:783–792
8.
Dubertret L (1999) Malignant atrophic papulosis (Degos’ disease). In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith AL, Katz SI, Fitzpatrick TB (eds) Dermatology in general medicine, vol 1. McGraw-Hill, New York, pp 1157–1161
9.
Ryan TJ (1998) Malignant atrophic papulosis. In: Champion RH, Burton JL, Burns DA, Breathnach SM (eds) Textbook of dermatology, vol 3. Blackwell, London, pp 2216–2217
10.
Katz SK, Mudd LJ, Roenigk HH (1997) Malignant atrophic papulosis (Degos’ disease) involving three generations of family. J Am Acad Dermatol 37:480–484PubMedCrossRef
11.
Ball E, Newburger A, Ackerman AB (2003) Degos’ disease: a distinctive pattern of disease, chiefly of lupus erythematosus, and not a specific disease per se. Am J Dermatopathol 25(4):308–320PubMedCrossRef
12.
Heymann WR (2009) Degos disease: considerations for reclassification. J Am Acad Dermatol 61(3):505–506PubMedCrossRef
13.
Howsden SM, Hodge DJ, Herndon JH, Freeman RG (1976) Malignant atrophic papulosis of Degos. Report of a patient who failed response to fibrinolytic therapy. Arch Dermatol 112:1582–1588PubMedCrossRef
14.
Zhu KJ, Zhou Q, Lin AH, Lu ZM, Cheng H (2007) The use of intravenous immunoglobulin in cutaneous and recurrent perforating intestinal Degos disease (malignant atrophic papulosis). Br J Dermatol 157(1):206–207PubMedCrossRef
Metadata
Title
A case of Degos disease successfully treated with corticosteroid combined with cyclophosphamide
Authors
Tomohiro Kameda
Hiroaki Dobashi
Kozo Yoneda
Kentaro Susaki
Toshiya Kuno
Koji Murao
Toshihiko Ishida
Publication date
01-07-2012
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 7/2012
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1436-z

Other articles of this Issue 7/2012

Rheumatology International 7/2012 Go to the issue

Original Article

TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor

Case Report

Misdiagnosis of Behçet’s disease with unknown protracted fever and chill after surgical excision of cardiac tumor

Original Article

Prevalence of hepatitis B surface antigen in patients with ankylosing spondylitis and its association with HLA-B27: a retrospective study from south China

Original Article

Evaluation of functional ability of rheumatoid arthritis based on HAQ score and BMD among South Indian patients

Original Article

Serum adenosine deaminase may predict disease activity in rheumatoid arthritis

Case Report

Proteus Takayasu’s arteritis with unusual intracranial granulomatosis as initial manifestation

ACC 2024 Congress Coverage

Cardiology Video

Highlights from the ACC 2024 Congress

Watch now

Watch official videos from the ACC congress summarizing key highlights from the last year in heart failure, cardiomyopathies, valvular disease, pulmonary vascular disease, and pediatric cardiology.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits