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Published in: Rheumatology International 7/2011

01-07-2011 | Original Article

Sexual functions in ankylosing spondylitis

Authors: Serpil Bal, Kaan Bal, Yasemin Turan, Gonca Deniz, Alev Gürgan, Işıl Karataş Berkit, Ömer Faruk Şendur

Published in: Rheumatology International | Issue 7/2011

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Abstract

Ankylosing spondylitis (AS) is a chronic inflammatory disorder of the axial skeleton. In recent years, several authors reported an increased prevalence of sexual dysfunction among AS patients. We aimed to find out, whether the prevalence of erectile dysfunction among AS patients is different from age-matched healthy controls. Thirty-seven male patients with AS who were diagnosed according to the modified New York criteria and 67 normal healthy controls (NHC) were included in this study. Clinical characteristics of patients including age, disease duration and morning stiffness were noted. Disease activity was evaluated by using Bath AS disease activity index (BASDAI), functional statement was evaluated by using Bath AS functional index, and scores of spinal measurements were done by using Bath AS metrology index. Erectile function is evaluated using the International Index of Erectile Function (IIEF) scoring system. Health-related quality of life was assessed by short form 36. The mean age of the patients and controls were 42.8 + 10.8 and 43.6 + 5.9 years (P = 0.666). The prevalence of erectile dysfunction in AS patients and NHC were 35.1 and 26.9%, respectively (P = 0.335). There was no statistically significant difference between IIEF domain scores of AS patients and NHC except for the sexual desire domain (P = 0.014). Duration of morning stiffness and BASDAI was negatively correlated with sexual desire and overall satisfaction; however, they have no negative impact on erectile function, orgasmic function and intercourse satisfaction domains of IIEF. In this report, we showed that only the sexual desire domain of IIEF was significantly lower in AS patients. The prevalence of erectile dysfunction among AS patients is similar to NHC, which is a finding contrary to previous reports. AS patients do not suffer from erectile dysfunction, they rather have problems of satisfaction from the intercourse.
Literature
1.
go back to reference Van Der Linden SJEF (2005) Spondyloarthropathies: ankylosing spondylitis. In: Harris Jr (ed) Kelley’s textbook of rheumatology, 7th edn. Elsevier Saunders, Philadelphia, pp 1125–1141 Van Der Linden SJEF (2005) Spondyloarthropathies: ankylosing spondylitis. In: Harris Jr (ed) Kelley’s textbook of rheumatology, 7th edn. Elsevier Saunders, Philadelphia, pp 1125–1141
2.
go back to reference Inman RD (1997) Seronegative spondyloarthropathies: Ankylosing spondylitis. In: Klippel JH (ed) Primer on the rheumatic diseases, 1st edn. Arthritis Foundation, Atlanta, pp 180–195 Inman RD (1997) Seronegative spondyloarthropathies: Ankylosing spondylitis. In: Klippel JH (ed) Primer on the rheumatic diseases, 1st edn. Arthritis Foundation, Atlanta, pp 180–195
3.
go back to reference Khan MA (2003) Clinical features of ankylosing spondylitis. In: Klippel JH (ed) Rheumatology. Mosby, London, pp 1161–1181 Khan MA (2003) Clinical features of ankylosing spondylitis. In: Klippel JH (ed) Rheumatology. Mosby, London, pp 1161–1181
4.
go back to reference Ward MM (1998) Quality of life in patients with ankylosing spondylitis. Rheum Dis Clin North Am 24:815PubMedCrossRef Ward MM (1998) Quality of life in patients with ankylosing spondylitis. Rheum Dis Clin North Am 24:815PubMedCrossRef
5.
go back to reference NIH Consensus Conference (1993) Impotence NIH Consensus Development Panel on Impotence. JAMA 270:83CrossRef NIH Consensus Conference (1993) Impotence NIH Consensus Development Panel on Impotence. JAMA 270:83CrossRef
6.
go back to reference Litwin MS, Nied RJ, Dhanani N (1998) Health-related quality of life in men with erectile dysfunction. J Gen Intern Med 13:159PubMedCrossRef Litwin MS, Nied RJ, Dhanani N (1998) Health-related quality of life in men with erectile dysfunction. J Gen Intern Med 13:159PubMedCrossRef
7.
go back to reference Gordon D, Beastall GH, Thomson JA, Sturrock RD (1986) Androgenic status and sexual function in males with rheumatoid arthritis and ankylosing spondylitis. Q J Med 60:671PubMed Gordon D, Beastall GH, Thomson JA, Sturrock RD (1986) Androgenic status and sexual function in males with rheumatoid arthritis and ankylosing spondylitis. Q J Med 60:671PubMed
8.
go back to reference Dincer U, Cakar E, Kiralp MZ, Dursun H (2007) Assessment of sexual dysfunction in male patients with Ankylosing Spondylitis. Rheumatol Int 27:561PubMedCrossRef Dincer U, Cakar E, Kiralp MZ, Dursun H (2007) Assessment of sexual dysfunction in male patients with Ankylosing Spondylitis. Rheumatol Int 27:561PubMedCrossRef
9.
go back to reference Pirildar T, Muezzinoglu T, Pirildar S (2004) Sexual function in ankylosing spondylitis: A study of 65 men. J Urol 171:1598PubMedCrossRef Pirildar T, Muezzinoglu T, Pirildar S (2004) Sexual function in ankylosing spondylitis: A study of 65 men. J Urol 171:1598PubMedCrossRef
10.
go back to reference van Berlo WTM, van de Wiel HBM, Taal E, Rasker JJ, Schultz WCMW, van Rijswijk MH (2007) Sexual functioning of people with rheumatoid arthritis: a multicenter study. Clin Rheumatol 26:30PubMedCrossRef van Berlo WTM, van de Wiel HBM, Taal E, Rasker JJ, Schultz WCMW, van Rijswijk MH (2007) Sexual functioning of people with rheumatoid arthritis: a multicenter study. Clin Rheumatol 26:30PubMedCrossRef
11.
go back to reference Cakar E, Dincer U, Kiralp MZ, Taskaynatan MA, Yasar E, Bayman EO et al (2007) Sexual problems in male ankylosing spondylitis patients: relationship with functionality, disease activity, quality of life, and emotional status. Clin Rheumatol 26:1607PubMedCrossRef Cakar E, Dincer U, Kiralp MZ, Taskaynatan MA, Yasar E, Bayman EO et al (2007) Sexual problems in male ankylosing spondylitis patients: relationship with functionality, disease activity, quality of life, and emotional status. Clin Rheumatol 26:1607PubMedCrossRef
12.
go back to reference Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A (1994) A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 21:2286PubMed Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A (1994) A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 21:2286PubMed
13.
go back to reference Akkoc Y, Karatepe AG, Akar S, Kirazli Y, Akkoc N (2005) A Turkish version of the Bath Ankylosing Spondylitis Disease Activity Index: reliability and validity. Rheumatol Int 25:280PubMedCrossRef Akkoc Y, Karatepe AG, Akar S, Kirazli Y, Akkoc N (2005) A Turkish version of the Bath Ankylosing Spondylitis Disease Activity Index: reliability and validity. Rheumatol Int 25:280PubMedCrossRef
14.
go back to reference Calin A, Garrett S, Whitelock H, Kennedy LG, O’Hea J, Mallorie P et al (1994) A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol 21:2281PubMed Calin A, Garrett S, Whitelock H, Kennedy LG, O’Hea J, Mallorie P et al (1994) A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol 21:2281PubMed
15.
go back to reference Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A (1994) Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 21:1694PubMed Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A (1994) Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 21:1694PubMed
17.
go back to reference Kocyigit H, Gulseren S, Erol A, Hizli N, Memis A (2003) The reliability and validity of the Turkish version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Clin Rheumatol 22:18PubMedCrossRef Kocyigit H, Gulseren S, Erol A, Hizli N, Memis A (2003) The reliability and validity of the Turkish version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Clin Rheumatol 22:18PubMedCrossRef
18.
go back to reference Doran S, Aridogan IA (2009) Erektil Disfonksiyon Degerlendirmesi (Chapt. 3). In: Kadioglu A, Basar M, Semerci B, Orhan I, Asci R, Yaman O et al (eds) Erkek ve Kadin Cinsel Sagligi, 1st edn. Turk Androloji Dernegi, Istanbul, pp 137–143 Doran S, Aridogan IA (2009) Erektil Disfonksiyon Degerlendirmesi (Chapt. 3). In: Kadioglu A, Basar M, Semerci B, Orhan I, Asci R, Yaman O et al (eds) Erkek ve Kadin Cinsel Sagligi, 1st edn. Turk Androloji Dernegi, Istanbul, pp 137–143
19.
go back to reference Gurbuz N, Tasci AI (2004) Dunya ve Turkiye’deki Erektil Disfonksiyon Epidemiyolojisi (chapt. 2). In: Kadioglu A, Basar M, Semerci B, Orhan I, Asci R, Yaman O et al (eds) Erkek ve Kadin Cinsel Sagligi, 1st edn. Turk Androloji Dernegi, Istanbul, pp 57–78 Gurbuz N, Tasci AI (2004) Dunya ve Turkiye’deki Erektil Disfonksiyon Epidemiyolojisi (chapt. 2). In: Kadioglu A, Basar M, Semerci B, Orhan I, Asci R, Yaman O et al (eds) Erkek ve Kadin Cinsel Sagligi, 1st edn. Turk Androloji Dernegi, Istanbul, pp 57–78
20.
go back to reference Shiri R, Koskimaki J, Hakkinen J, Tammela TL, Auvinen A, Hakama M (2006) Effect of nonsteroidal anti-inflammatory drug use on the incidence of erectile dysfunction. J Urol 175:1812PubMedCrossRef Shiri R, Koskimaki J, Hakkinen J, Tammela TL, Auvinen A, Hakama M (2006) Effect of nonsteroidal anti-inflammatory drug use on the incidence of erectile dysfunction. J Urol 175:1812PubMedCrossRef
21.
go back to reference Ireland A, Jewell DP (1989) Sulfasalazine-induced impotence: a beneficial resolution with olsalazine? J Clin Gastroenterol 11:711PubMed Ireland A, Jewell DP (1989) Sulfasalazine-induced impotence: a beneficial resolution with olsalazine? J Clin Gastroenterol 11:711PubMed
22.
go back to reference Elst P, Sybesma T, van der Stadt RJ, Prins AP, Muller WH, den Butter A (1984) Sexual problems in rheumatoid arthritis and ankylosing spondylitis. Arthritis Rheum 27:217PubMedCrossRef Elst P, Sybesma T, van der Stadt RJ, Prins AP, Muller WH, den Butter A (1984) Sexual problems in rheumatoid arthritis and ankylosing spondylitis. Arthritis Rheum 27:217PubMedCrossRef
23.
go back to reference Bal K, Oder M, Sahin AS, Karatas CT, Demir O, Can E et al (2007) Prevalence of metabolic syndrome and its association with erectile dysfunction among urologic patients: metabolic backgrounds of erectile dysfunction. Urology 69:356PubMedCrossRef Bal K, Oder M, Sahin AS, Karatas CT, Demir O, Can E et al (2007) Prevalence of metabolic syndrome and its association with erectile dysfunction among urologic patients: metabolic backgrounds of erectile dysfunction. Urology 69:356PubMedCrossRef
Metadata
Title
Sexual functions in ankylosing spondylitis
Authors
Serpil Bal
Kaan Bal
Yasemin Turan
Gonca Deniz
Alev Gürgan
Işıl Karataş Berkit
Ömer Faruk Şendur
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 7/2011
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1406-5

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