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01-08-2010 | Case Report

Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP)

Authors: Felix Wantke, Meinhard Kneussl, Marianne Hubner, Kurt Derfler, Thomas Brücke, Sabine Schmaldienst

Published in: Rheumatology International | Issue 10/2010

Abstract

We report of a 46-year-old female patient with cryptogen organizing pneumonia preceeding the rare SRP positive necrotising myositis without cardiac involvement and no sign of dysphagia. Myositis showed full regression without oral immune suppression but with extracorporeal treatment, performed as a combined therapy of plasmaexchange and immunoadsorption. After 33-month of treatment, anti-SRP antibodies were not detectable any more.

British Thoracic Society Interstitial Lung Disease Guideline Group (2008) Interstitial lung disease guideline. Thorax 63(Suppl V):v1–v58CrossRef

American Thoracic Society/European Respiratory Society (2002) International multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 165:277–304

Katzenstein AL, Mukhopadhyay S, Myers JL (2008) Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases. Hum Pathol 39:1275–1294. doi:10.1016/j.humpath.2008.05.009 CrossRefPubMed

Cordier JF, Costabel U, duBois R (2004) Cryptogenic organizing pneumonia. Orphanet encylcopedia, October 2004. http://www.orphanet/data/patho/GB/uk-CryptoOrgPneum.pdf

Kao AH, Lacomis D, Lucas M, Fertig N, Oddis CV (2004) Anti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy. Arthritis Rheum 50:209–215. doi:10.1002/art.11484 CrossRefPubMed

Nelson RP, Ballow M (2003) Immunomodulation and immunotherapy: drugs, cytokines, cytokine receptors and antibodies. J Allergy Clin Immunol 111:S720–S732. doi:10.1067/mai.2003.146 CrossRefPubMed

Dittrich E, Schmaldienst S, Langer M, Jansen M, Hörl WH, Derfler K (2002) Immunoadsorption and plasma exchange in pregnancy. Kidney Blood Press Res 25:232–239. doi:10.1159/000066343 CrossRefPubMed

Schmaldienst S, Müllner M, Goldammer A, Spitzauer S, Banyai S, Hörl WH, Derfler K (2001) Intravenous immunoglobulin application following immunoadsorption: benefit or risk in patients with autoimmune diseases? Rheumatology 40:513–521. doi:10.1093/rheumatology/40.5.513 CrossRefPubMed

Hengstman GJ, ter Laak HJ, Vree Egberts WT, Lundberg IE, Moutsopoulos HM, Vencovsky J, Doria A, Mosca M, van Venrooij WJ, van Engelen BG (2006) Anti-signal recognition particle autoantibodies: marker of a necrotising myopathy. Ann Rheum Dis 65:1635–1638. doi:10.1136/ard.2006.052191 CrossRefPubMed

10.

Knoell KA, Hook M, Grice P, Hendrix J (1999) Dermatomyositis associated with bronchiolitis obliterans organizing pneumonia. J Am Acad Dermatol 40:328–330. doi:10.1016/S0190-9622(99)70478-0 CrossRefPubMed

11.

Dalakas MC, Hohlfeld R (2003) Polymyositis and dermatomyositis. Lancet 362:971–982. doi:10.1016/S0140-6736(03)14368-1 CrossRefPubMed

12.

Choi EHS, Isenberg DA (2002) Treatment of dermatomyositis and polymyositis. Rheumatology 41:7–13. doi:10.1093/rheumatology/41.1.7 CrossRef

13.

Brouwer R, Hengstman GJ, Vree Egberts W, Ehrfeld H, Bozic B, Ghirardello A, Grøndal G, Hietarinta M, Isenberg D, Kalden JR, Lundberg I, Moutsopoulos H, Roux-Lombard P, Vencovsky J, Wikman A, Seelig HP, van Engelen BG, van Venrooij WJ (2001) Autoantibody profiles in sera of European patients with myositis. Ann Rheum Dis 60:116–123. doi:10.1136/ard.60.2.116 CrossRefPubMed

14.

Wild K, Rosendal KR, Sinning I (2004) A structural step into the SRP cycle—microreview. Mol Microbiol 53:357–363. doi:10.1111/j.1365-2958.2004.04139.x CrossRefPubMed

15.

Kalenian M, Zweiman B (1997) Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia and anti-Jo-1 antibodies—an interesting association. Clin Diagn Lab Immunol 4:236–240PubMed

16.

Imaski T, Tanaka S, Ogura T, Ishikawa A, Takahashi T (1996) Polymyositis and Sjögren’s syndrome associated with bronchiolitis obliterans organizing pneumonia. Intern Med 35:231–235. doi:10.2169/internalmedicine.35.231 CrossRef

17.

Fata F, Rathore R, Schiff C, Herzlich BC (1997) Bronchiolitis obliterans organizing pneumonia as the first manifestation of polymyositis. South Med J 90:227–230PubMed

18.

Tazelaar HD, Viggiano RW, Pickersgill J, Colby TV (1990) Interstitial lung disease in polymyositis and dermatomyositis: clinical features and prognosis as correlated with histological findings. Am Rev Respir Dis 141:727–733PubMed

19.

Lee CS, Chen TL, Tzen CY, Lin FJ, Peng MJ, Wu CL, Chen PJ (2002) Idiopathic inflammatory myopathy with diffuse alveolar damage. Clin Rheumatol 21:391–396. doi:10.1007/s100670200104 CrossRefPubMed

20.

Suzuki S, Satoh T, Sato S, Otomo M, Hirayama Y, Sato H, Kawai M, Ishihara T, Suzuki N, Kuwana M (2008) Clinical utility of anti-signal recognition particle antibody in the differential diagnosis of myopathy. Rheumatology 47:1539–1542. doi:10.1093/rheumatology/ken325 CrossRefPubMed

21.

Rouster-Stevens KA, Pachman LM (2008) Autoantibody to signal recognition particle in African American girls with juvenile polymyositis. J Rheumatol 35:927–929PubMed

Title: Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP)
Authors: Felix Wantke
Meinhard Kneussl
Marianne Hubner
Kurt Derfler
Thomas Brücke
Sabine Schmaldienst
Publication date: 01-08-2010
Publisher: Springer-Verlag
Published in: Rheumatology International / Issue 10/2010
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-009-1059-4

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