Published in:
01-10-2009 | Case Report
Successful twin pregnancy while on cyclophosphamide therapy in a patient with lupus nephritis
Authors:
Rajiva Gupta, S. Deepanjali, M. M. Thabah, P. Kaur, S. Gupta
Published in:
Rheumatology International
|
Issue 12/2009
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Excerpt
Intravenous pulse cyclophosphamide is the standard therapy for the treatment of lupus nephritis [
1]. Menstrual irregularities and premature ovarian failure can result from the prolonged use of cyclophosphamide [
2,
3]. The teratogenic potential of cyclophosphamide has also been reported [
4], and its effect has been proven in humans [
5]. Its effect on pregnancy outcomes has not been studied well. We report a case of successful twin pregnancy during treatment with cyclophosphamide in a patient with lupus nephritis. …