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01-09-2006 | Case Report

Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement

Authors: Ayşe Tosun, Gül Serdaroğlu, Mehmet Tayyip Aslan, Muzaffer Polat, Taner Akalın, Hasan Tekgul, Sarenur Gökben

Published in: Rheumatology International | Issue 11/2006

Abstract

Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He had a rapidly progressive course and died in 7 weeks after the onset of the disease despite steroid and immunosuppressive treatment. The second case (a 14-year-old boy) was presented with myositis complicated with hepatitis. He also had a chronic course of JDM with unfavorable outcome. It appears that the prognosis of patients with severe JDM is related with the degree of autoimmune vasculitis on extra musculocutaneous involvement.

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Title: Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
Authors: Ayşe Tosun
Gül Serdaroğlu
Mehmet Tayyip Aslan
Muzaffer Polat
Taner Akalın
Hasan Tekgul
Sarenur Gökben
Publication date: 01-09-2006
Publisher: Springer-Verlag
Published in: Rheumatology International / Issue 11/2006
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-006-0141-4

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