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Rheumatology International
Published in: Rheumatology International 5/2005

01-07-2005 | Case Report

Successful treatment of pure red cell aplasia associated with systemic lupus erythematosus with oral danazol and steroid

Authors: Alice YK Chan, Edmund K Li, LS Tam, Gregory Cheng, Paul CL Choi

Published in: Rheumatology International | Issue 5/2005

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Abstract

We describe a middle-aged Chinese systemic lupus erythematosus (SLE) patient developing steroid refractory and transfusion dependent red cell aplasia. Oral danazol 200 mg twice per day was started together with low-dose prednisolone therapy. There was no further recurrence of anemia 1 month after this combined therapy.
Literature
1.
Choi BG, Yoo WH (2002) Successful treatment of pure red cell aplasia with plasmapheresis in a patient with systemic lupus erythematosus. Yonsei Med J 43(2):274–278PubMed
2.
Kiely PD, McGuckin CP, Collins DA, Bevan DH et al (1995) Erythrocyte aplasia and systemic lupus erythematosus. Lupus 4:407–411PubMed
3.
Linardaki GD, Boki KA, Fartakis A, Tzioufas AG (1999) Pure red cell aplasia as presentation of systemic lupus erythematosus: Antibodies to erythropoietin. Scand J Rheumatol 28:189–191CrossRefPubMed
4.
Abkowitz JL, Kadin ME, Powell JS, Adamson JW (1986) Pure red cell aplasia: lymphocyte inhibition of erythropoiesis. Br J Haematol 63:59–67PubMed
5.
Clark DA, Dessypris EN, Krantz SB (1984) Studies on pure red cell aplasia. XI. Results of immunosuppressive treatment of 37 patients. Blood 63:277PubMed
6.
Winkler A, Jackson RW, Kay DS (1988) High dose intravenous cyclophosphamide treatment of systemic lupus erythematosus associated aplastic anemia. Arthritis Rheum 31:693PubMed
7.
Duarte-Salazar C, Cazarin-Barrientos J, Goycochea-Robles MV, Collazo-Jaloma J et al (2000) Successful treatment of pure red cell aplasia associated with systemic lupus erythematosus with cyclosporin A. Rheumatol 39:1155–1157CrossRef
8.
Ilan Y, Naparstek Y (1993) Pure red cell aplasia associated with systemic lupus erythematosus: remission after a single course of intravenous immunoglobulin. Acta Haematol 89:152–154PubMed
9.
Lippman SM, Durie BGM, Garewal HS, Giordano G et al (1986) Efficacy of danazol in pure red cell aplasia. Am J Hematol 23:373–379PubMed
10.
Roubinian JR, Papoian R, Talal N (1977) Androgenic hormones modulate autoantibody responses and improve survival in murine lupus. J Clin Invest 59:1066–1070PubMed
11.
Roubinian JR, Talal N, Greenspan JS, Goodman JR et al (1978) Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med 147:1568–1583CrossRefPubMed
12.
Michalski JP, McCombs CC, Roubinian JR, Talal N (1983) Effect of androgen therapy on survival and suppressor cell activity in aged NZB/NZW F1 hybrid mice. Clin Exp Immunol 52:229–233PubMed
13.
Stein CM (2001) Immunoregulatory drugs. In: Ruddy S (ed) Kelley’s Textbook of Rheumatology. W.B. Saunders, Philadelphia, pp 879–898
Metadata
Title
Successful treatment of pure red cell aplasia associated with systemic lupus erythematosus with oral danazol and steroid
Authors
Alice YK Chan
Edmund K Li
LS Tam
Gregory Cheng
Paul CL Choi
Publication date
01-07-2005
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 5/2005
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-004-0521-6

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