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Published in:

01-04-2008 | Review

Immunological mechanisms in glaucoma

Authors: F. Grus, D. Sun

Published in: Seminars in Immunopathology | Issue 2/2008

Abstract

Glaucoma is one of the most frequent causes of blindness worldwide. The elevated intraocular pressure does not explain glaucoma in all patients but can be considered as a risk factor of the disease. There are some evidences that autoimmune mechanisms may be involved in this disorder. This review attempts to demonstrate the findings about autoimmune mechanisms in glaucoma patients. Consistent up- and down-regulations in the autoantibody profiles against ocular antigens are present in glaucoma patients. These changes in natural autoimmunity could be found in independent study populations and might be a promising tool for glaucoma detection.

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Title: Immunological mechanisms in glaucoma
Authors: F. Grus
D. Sun
Publication date: 01-04-2008
Publisher: Springer-Verlag
Published in: Seminars in Immunopathology / Issue 2/2008
Print ISSN: 1863-2297
Electronic ISSN: 1863-2300
DOI: https://doi.org/10.1007/s00281-008-0105-8

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