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Published in: Annals of Hematology 11/2019

01-11-2019 | Acidosis | Letter to the Editor

Fatal type B lactic acidosis in a patient with end-stage liver disease related to homozygous sickle cell disease

Authors: Véronique Masy, Etienne Sokal, Nadejda Ranguelov, Bénédicte Brichard, Pierre-François Laterre, Philippe Hantson

Published in: Annals of Hematology | Issue 11/2019

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Excerpt

Hepatic involvement by sickle cell disease (SCD) can result in a variety of symptoms ranging from mild to life-threatening. Acute intrahepatic cholestasis is a rare but often fatal condition, with multi-organ failure as a terminal event. The following observation is suggesting that extreme hyperbilirubinemia may be associated with energetic failure. …
Literature
1.
go back to reference Finsterer J, Scorza FA (2017) Effects of antiepileptic drugs on mitochondrial functions, morphology, kinetics, biogenesis, and survival. Epilepsy Res. 136:5–11CrossRef Finsterer J, Scorza FA (2017) Effects of antiepileptic drugs on mitochondrial functions, morphology, kinetics, biogenesis, and survival. Epilepsy Res. 136:5–11CrossRef
2.
go back to reference Lipka K, Bülow HH (2003) Lactic acidosis following convulsions. Acta Anaesthesiol Scand. 47:616–618CrossRef Lipka K, Bülow HH (2003) Lactic acidosis following convulsions. Acta Anaesthesiol Scand. 47:616–618CrossRef
3.
go back to reference Karacaoglu PK, Asma S, Korur A et al (2016) East Mediterranean region sickle cell disease mortality trial: retrospective multicenter cohort analysis of 735 patients. Ann Hematol. 95:993–1000CrossRef Karacaoglu PK, Asma S, Korur A et al (2016) East Mediterranean region sickle cell disease mortality trial: retrospective multicenter cohort analysis of 735 patients. Ann Hematol. 95:993–1000CrossRef
4.
go back to reference Manci EA, Culberson DE, Yang YM, Gardner TM, Powell R, Haynes J Jr, Shah AK, Mankad VN, Investigators of the Cooperative Study of Sickle Cell Disease (2003) Causes of death in sickle cell disease: an autopsy study. Br J Haematol. 123:359–365CrossRef Manci EA, Culberson DE, Yang YM, Gardner TM, Powell R, Haynes J Jr, Shah AK, Mankad VN, Investigators of the Cooperative Study of Sickle Cell Disease (2003) Causes of death in sickle cell disease: an autopsy study. Br J Haematol. 123:359–365CrossRef
5.
go back to reference Haydek JP, Taborda C, Shah R, Reshamwala PA, McLemore M, Rassi FE, Chawla S (2019) Extreme hyperbilirubinemia: an indicator of morbidity and mortality in sickle cell disease. World J Hepatol. 11:287–293CrossRef Haydek JP, Taborda C, Shah R, Reshamwala PA, McLemore M, Rassi FE, Chawla S (2019) Extreme hyperbilirubinemia: an indicator of morbidity and mortality in sickle cell disease. World J Hepatol. 11:287–293CrossRef
Metadata
Title
Fatal type B lactic acidosis in a patient with end-stage liver disease related to homozygous sickle cell disease
Authors
Véronique Masy
Etienne Sokal
Nadejda Ranguelov
Bénédicte Brichard
Pierre-François Laterre
Philippe Hantson
Publication date
01-11-2019
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 11/2019
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-019-03822-8

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