Published in:
01-11-2019 | Acidosis | Letter to the Editor
Fatal type B lactic acidosis in a patient with end-stage liver disease related to homozygous sickle cell disease
Authors:
Véronique Masy, Etienne Sokal, Nadejda Ranguelov, Bénédicte Brichard, Pierre-François Laterre, Philippe Hantson
Published in:
Annals of Hematology
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Issue 11/2019
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Excerpt
Hepatic involvement by sickle cell disease (SCD) can result in a variety of symptoms ranging from mild to life-threatening. Acute intrahepatic cholestasis is a rare but often fatal condition, with multi-organ failure as a terminal event. The following observation is suggesting that extreme hyperbilirubinemia may be associated with energetic failure. …