Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Annals of Hematology
Published in: Annals of Hematology 9/2019

01-09-2019 | Hemolytic Anemia | Letter to the Editor

Hb Fairfax [HBB:c.285_286insGAGCTGCACTGTGAC] in a Brazilian patient with severe hemolytic anemia—identification and functional study

Authors: S. E. Jorge, C. Lanaro, D. M. Albuquerque, P. H. Nascimento, G. A. Pedroso, S. C. Oliveira, M. R. P. Grigoleto, M. N. N. Santos, F. F. Costa, M. F. Sonati

Published in: Annals of Hematology | Issue 9/2019

Login to get access

Excerpt

Dear Editor, …
Literature
1.
Greenberg J, Fairbanks VF, Hoyer J, Thibodeau SN, Fairfax VA (1997) Hemoglobin Fairfax, a tandem duplication of β90–94 inserted between β94–β95 (proved by DNA sequence analysis): a previously undescribed unstable hemoglobin variant associated with severe hemolytic anemia and stroke during early childhood [abstract]. Blood 90(Suppl. 1):27B
2.
3.
4.
Dacie JV, Lewis SM (1995) Practical haematology, 8th edn. Churchill Livingstone, New York
5.
6.
Hartelveld CL, Thelen MH, Rutten JJ, Leuverman J, Akkermans N, van Delft P, Arlesteijn S, Giordano PC (2005) HbGeldrop St Anna [beta94(FG1)Asp-->Tyr]: a new hemoglobin variant observed in a diabetic patient. Hemoglobin 29(2):107–112
7.
Como PF, Kennett D, Wilkinson T, Kronenberg H (1983) A new hemoglobin with high oxygen affinity - hemoglobin Bunbury: alpha 2 beta 2 [94 (FG1) Asp replaced by Asn]. Hemoglobin 7(5):413–421CrossRefPubMed
8.
Wajcman H, Aguilar I Bascompete JL, Labie D, Poyart C, Bohn B (1982) Structural and functional studies of hemoglobin Barcelona (alpha 2 beta 2 94 Asp (FG1) replaced by His). Consequences of altering an important intra chain salt bridge involved in the alkaline Bohr effect. J Mol Biol 156(1):185–202CrossRefPubMed
9.
Dash S, Das R (2004) Late emergence of polycythemia in a case of Hb Chandigarh [beta94(FG1)Asp-->Gly]. Hemoglobin 28(3):273–274CrossRefPubMed
Metadata
Title
Hb Fairfax [HBB:c.285_286insGAGCTGCACTGTGAC] in a Brazilian patient with severe hemolytic anemia—identification and functional study
Authors
S. E. Jorge
C. Lanaro
D. M. Albuquerque
P. H. Nascimento
G. A. Pedroso
S. C. Oliveira
M. R. P. Grigoleto
M. N. N. Santos
F. F. Costa
M. F. Sonati
Publication date
01-09-2019
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 9/2019
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-019-03728-5

Other articles of this Issue 9/2019

Annals of Hematology 9/2019 Go to the issue

Letter to the Editor

Risk factors of infection in patients with hematological malignancy

Original Article

Age-dependent determinants of infectious complications profile in children and adults after hematopoietic cell transplantation: lesson from the nationwide study

Letter to the Editor

Molecular response of CSF3R T618I harboring chronic neutrophilic leukemia after induction chemotherapy linked to cord blood transplantation

Original Article

Incidence and outcome of invasive fungal disease after front-line intensive chemotherapy in patients with acute myeloid leukemia: impact of antifungal prophylaxis

Original Article

Direct comparison of two extended-half-life recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A

Original Article

Clinical characteristics and outcomes of primary adrenal diffuse large B cell lymphoma in a large contemporary cohort: a SEER-based analysis
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits