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Annals of Hematology
Published in: Annals of Hematology 10/2015

01-10-2015 | Letter to the Editor

Chronic myelomonocytic leukemia coexisting with monoclonal gammopathy: concomitant response to azacitidine of both disorders

Authors: Pasquale Niscola, Agostina Siniscalchi, Andrea Tendas, Laura Scaramucci, Stefano Fratoni, Paolo de Fabritiis, Tommaso Caravita

Published in: Annals of Hematology | Issue 10/2015

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Excerpt

Dear Editor, …
Literature
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Raz I, Polliack A (1984) Coexistence of myelomonocytic leukemia and monoclonal gammopathy or myeloma. Simultaneous presentation in three patients. Cancer 53(1):83–5CrossRefPubMed
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Berner Y, Berrebi A (1986) Myeloproliferative disorders and nonmyelomatous paraprotein. A study of five patients and review of the literature. Isr J Med Sci 22(2):109–12PubMed
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Maeda T, Ashie T, Kikuiri K, Ishiyama N, Takakura M, Ise T (1989) Chronic myelomonocytic leukemia with polyneuropathy and IgA-paraprotein. Jpn J Med 28(6):709–16CrossRefPubMed
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Tessema M, Länger F, Dingemann J, Ganser A, Kreipe H, Lehmann U (2003) Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML). Leukemia 17(5):910–8CrossRefPubMed
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Galm O, Wilop S, Reichelt J, Jost E, Gehbauer G, Herman JG, Osieka R (2004) DNA methylation changes in multiple myeloma. Leukemia 18(10):1687–92CrossRefPubMed
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Piras G, Monne M, Palmas AD, Calvisi A, Asproni R, Vacca F, Pilo L, Gabbas A, Latte G (2014) Methylation analysis of the phosphates and tensin homologue on chromosome 10 gene (PTEN) in multiple myeloma. Clin Epigenetics 6(1):16PubMedCentralCrossRefPubMed
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Heller G, Schmidt WM, Ziegler B, Holzer S, Müllauer L, Bilban M, Zielinski CC, Drach J, Zöchbauer-Müller S (2008) Genome-wide transcriptional response to 5-aza-2′-deoxycytidine and trichostatin a in multiple myeloma cells. Cancer Res 68(1):44–54CrossRefPubMed
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Cheson BD, Greenberg PL, Bennett JM, Lowenberg B, Wijermans PW, Nimer SD, Pinto A, Beran M, de Witte TM, Stone RM, Mittelman M, Sanz GF, Gore SD, Schiffer CA, Kantarjian H (2006) Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 108(2):419–25CrossRefPubMed
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Onida F, Barosi G, Leone G, Malcovati L, Morra E, Santini V, Specchia G, Tura S (2013) Management recommendations for chronic myelomonocytic leukemia: consensus statements from the SIE, SIES. GITMO groups. Haematologica 98(9):1344–52PubMedCentralCrossRefPubMed
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Tendas A, Cupelli L, Siniscalchi A, Scaramucci L, Giovannini M, Dentamaro T, Perrotti A, Caravita T, de Fabritiis P, Niscola P (2014) Azacitidine in chronic myelomonocytic leukemia: an effective and manageable approach. Mediterr J Hematol Infect Dis 6(1):e2014020PubMedCentralCrossRefPubMed
Metadata
Title
Chronic myelomonocytic leukemia coexisting with monoclonal gammopathy: concomitant response to azacitidine of both disorders
Authors
Pasquale Niscola
Agostina Siniscalchi
Andrea Tendas
Laura Scaramucci
Stefano Fratoni
Paolo de Fabritiis
Tommaso Caravita
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 10/2015
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-015-2431-y

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