Skip to main content
Top
Published in: Annals of Hematology 7/2015

Open Access 01-07-2015 | Original Article

Trends in quality of non-Hodgkin’s lymphoma care: is it getting better?

Authors: J. J. C. Stienen, P. B. Ottevanger, L. Wennekes, S. A. M. van de Schans, H. M. Dekker, R. W. M. van der Maazen, J. H. J. M. van Krieken, N. M. A. Blijlevens, R. P. M. G. Hermens, On behalf of the PEARL study group

Published in: Annals of Hematology | Issue 7/2015

Login to get access

Abstract

This study outlines trends in quality of delivered non-Hodgkin’s lymphoma (NHL) care in the Netherlands between 2007 and 2011 and to what extend this was influenced by the national Visible Care program, which aimed at increasing transparency by providing insight into the quality of healthcare. We analyzed data collected from medical records in two observational studies, combined into 20 validated quality indicators (QIs) of which 6 were included in the national program. A random sample of 771 patients, diagnosed with NHL in 26 Dutch hospitals, was examined. Multilevel regression analyses were used to assess differences in quality of NHL care and to provide insight into the effect of the national program. We reported improved adherence to only 3 out of 6 QIs involved in the national program and none of the other 14 validated QIs. Improvement was shown for performance of all recommended staging techniques (from 26  to  43 %), assessment of International Prognostic Index (from 21  to  43 %), and multidisciplinary discussion of patients (from 23  to  41 %). We found limited improvement in quality of NHL care between 2007 and 2011; improvement potential (<80 % adherence) was still present for 13 QIs. The national program seems to have a small positive effect, but has not influenced all 20 indicators which represent the most important, measurable parts in quality of NHL care. These results illustrate the need for tailored implementation and quality improvement initiatives.
Literature
4.
go back to reference Dotan E, Aggarwal C, Smith MR (2010) Impact of rituximab (Rituxan) on the treatment of B-cell non-Hodgkin's lymphoma. P T 35(3):148–157PubMedCentralPubMed Dotan E, Aggarwal C, Smith MR (2010) Impact of rituximab (Rituxan) on the treatment of B-cell non-Hodgkin's lymphoma. P T 35(3):148–157PubMedCentralPubMed
5.
go back to reference Lindenmeyer LP, Hegele V, Caregnato JP, Wust D, Grazziotin L, Stoll P (2013) Follow-up of patients receiving rituximab for diffuse large B cell lymphoma: an overview of systematic reviews. Ann Hematol. doi:10.1007/s00277-013-1811-4 PubMed Lindenmeyer LP, Hegele V, Caregnato JP, Wust D, Grazziotin L, Stoll P (2013) Follow-up of patients receiving rituximab for diffuse large B cell lymphoma: an overview of systematic reviews. Ann Hematol. doi:10.​1007/​s00277-013-1811-4 PubMed
6.
go back to reference Clarke C, O'Malley C (2007) Chapter 28: non-Hodgkin lymphoma. SEER survival monograph: cancer survival among adults: U.S. SEER program, 1988-2001, patient and tumor characteristics., vol Pub.No. 07-6215. National Cancer Institute, NIH, Bethesda Clarke C, O'Malley C (2007) Chapter 28: non-Hodgkin lymphoma. SEER survival monograph: cancer survival among adults: U.S. SEER program, 1988-2001, patient and tumor characteristics., vol Pub.No. 07-6215. National Cancer Institute, NIH, Bethesda
9.
go back to reference Tilly H, Vitolo U, Walewski J, da Silva MG, Shpilberg O, Andre M, Pfreundschuh M, Dreyling M, Group EGW (2012) Diffuse large B-cell lymphoma (DLBCL): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 23(Suppl 7):vii78–vii82. doi:10.1093/annonc/mds273 CrossRefPubMed Tilly H, Vitolo U, Walewski J, da Silva MG, Shpilberg O, Andre M, Pfreundschuh M, Dreyling M, Group EGW (2012) Diffuse large B-cell lymphoma (DLBCL): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 23(Suppl 7):vii78–vii82. doi:10.​1093/​annonc/​mds273 CrossRefPubMed
10.
go back to reference Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Fisher RI, Glenn MJ, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press O, Rabinovitch R, Reddy N, Reid E, Sokol L, Swinnen LJ, Tsien C, Vose JM, Yahalom J, Zafar N, Dwyer M, Sundar H (2014) Non-Hodgkin's lymphomas, Version 2.2014. J Natl Compr Cancer Netw: JNCCN 12(6):916–946PubMed Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Fisher RI, Glenn MJ, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press O, Rabinovitch R, Reddy N, Reid E, Sokol L, Swinnen LJ, Tsien C, Vose JM, Yahalom J, Zafar N, Dwyer M, Sundar H (2014) Non-Hodgkin's lymphomas, Version 2.2014. J Natl Compr Cancer Netw: JNCCN 12(6):916–946PubMed
11.
go back to reference Campbell SM, Braspenning J, Hutchinson A, Marshall MN (2003) Research methods used in developing and applying quality indicators in primary care. BMJ 326(7393):816–819. doi:10.1136/bmj.326.7393.816 Campbell SM, Braspenning J, Hutchinson A, Marshall MN (2003) Research methods used in developing and applying quality indicators in primary care. BMJ 326(7393):816–819. doi:10.​1136/​bmj.​326.​7393.​816
13.
14.
go back to reference Wennekes L, Ottevanger PB, Raemaekers JM, Schouten HC, de Kok MW, Punt CJ, Grol RP, Wollersheim HC, Hermens RP (2011) Development and measurement of guideline-based indicators for patients with non-Hodgkin's lymphoma. J Clin Oncol 29(11):1436–1444. doi:10.1200/jco.2010.30.1622 CrossRefPubMed Wennekes L, Ottevanger PB, Raemaekers JM, Schouten HC, de Kok MW, Punt CJ, Grol RP, Wollersheim HC, Hermens RP (2011) Development and measurement of guideline-based indicators for patients with non-Hodgkin's lymphoma. J Clin Oncol 29(11):1436–1444. doi:10.​1200/​jco.​2010.​30.​1622 CrossRefPubMed
17.
go back to reference van der Geest LG, Krijnen P, Wouters MW, Erkelens WG, Marinelli AW, Nortier HJ, Tollenaar RA, Struikmans H, Comprehensive Cancer Centre the Netherlands LL (2012) Improved guideline compliance after a 3-year audit of multidisciplinary colorectal cancer care in the western part of the Netherlands. J Surg Oncol 106(1):1–9. doi:10.1002/jso.23038 CrossRefPubMed van der Geest LG, Krijnen P, Wouters MW, Erkelens WG, Marinelli AW, Nortier HJ, Tollenaar RA, Struikmans H, Comprehensive Cancer Centre the Netherlands LL (2012) Improved guideline compliance after a 3-year audit of multidisciplinary colorectal cancer care in the western part of the Netherlands. J Surg Oncol 106(1):1–9. doi:10.​1002/​jso.​23038 CrossRefPubMed
18.
go back to reference Foster D (2013) Essential reading for smart spending: dr Foster hospital guide 2013 Foster D (2013) Essential reading for smart spending: dr Foster hospital guide 2013
19.
go back to reference Campbell SM, Cantrill JA, Roberts D (2000) Prescribing indicators for UK general practice: Delphi consultation study. BMJ 321(7258):425–428 Campbell SM, Cantrill JA, Roberts D (2000) Prescribing indicators for UK general practice: Delphi consultation study. BMJ 321(7258):425–428
20.
go back to reference Stienen JJ, Hermens RP, Wennekes L, van de Schans SA, Dekker HM, Blijlevens NM, van der Maazen RW, Adang EM, van Krieken JH, Ottevanger PB (2013) Improvement of hospital care for patients with non-Hodgkin's lymphoma: protocol for a cluster randomized controlled trial (PEARL study). Implementation Science: IS 8:77. doi:10.1186/1748-5908-8-77 CrossRefPubMedCentralPubMed Stienen JJ, Hermens RP, Wennekes L, van de Schans SA, Dekker HM, Blijlevens NM, van der Maazen RW, Adang EM, van Krieken JH, Ottevanger PB (2013) Improvement of hospital care for patients with non-Hodgkin's lymphoma: protocol for a cluster randomized controlled trial (PEARL study). Implementation Science: IS 8:77. doi:10.​1186/​1748-5908-8-77 CrossRefPubMedCentralPubMed
21.
go back to reference Mourad SM, Nelen WL, Hermens RP, Bancsi LF, Braat DD, Zielhuis GA, Grol RP, Kremer JA (2008) Variation in subfertility care measured by guideline-based performance indicators. Hum Reprod 23(11):2493–2500. doi:10.1093/humrep/den281 CrossRefPubMed Mourad SM, Nelen WL, Hermens RP, Bancsi LF, Braat DD, Zielhuis GA, Grol RP, Kremer JA (2008) Variation in subfertility care measured by guideline-based performance indicators. Hum Reprod 23(11):2493–2500. doi:10.​1093/​humrep/​den281 CrossRefPubMed
22.
go back to reference Ouwens MM, Marres HA, Hermens RR, Hulscher MM, van den Hoogen FJ, Grol RP, Wollersheim HC (2007) Quality of integrated care for patients with head and neck cancer: development and measurement of clinical indicators. Head Neck 29(4):378–386. doi:10.1002/hed.20532 CrossRefPubMed Ouwens MM, Marres HA, Hermens RR, Hulscher MM, van den Hoogen FJ, Grol RP, Wollersheim HC (2007) Quality of integrated care for patients with head and neck cancer: development and measurement of clinical indicators. Head Neck 29(4):378–386. doi:10.​1002/​hed.​20532 CrossRefPubMed
24.
go back to reference Campbell MK, Fayers PM, Grimshaw JM (2005) Determinants of the intracluster correlation coefficient in cluster randomized trials: the case of implementation research. Clin Trials 2(2):99–107CrossRefPubMed Campbell MK, Fayers PM, Grimshaw JM (2005) Determinants of the intracluster correlation coefficient in cluster randomized trials: the case of implementation research. Clin Trials 2(2):99–107CrossRefPubMed
25.
go back to reference Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159–174CrossRefPubMed Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159–174CrossRefPubMed
26.
go back to reference Cheson BD, Pfistner B, Juweid ME, Gascoyne RD, Specht L, Horning SJ, Coiffier B, Fisher RI, Hagenbeek A, Zucca E, Rosen ST, Stroobants S, Lister TA, Hoppe RT, Dreyling M, Tobinai K, Vose JM, Connors JM, Federico M, Diehl V, International Harmonization Project on L (2007) Revised response criteria for malignant lymphoma. J Clin Oncol 25(5):579–586. doi:10.1200/jco.2006.09.2403 CrossRefPubMed Cheson BD, Pfistner B, Juweid ME, Gascoyne RD, Specht L, Horning SJ, Coiffier B, Fisher RI, Hagenbeek A, Zucca E, Rosen ST, Stroobants S, Lister TA, Hoppe RT, Dreyling M, Tobinai K, Vose JM, Connors JM, Federico M, Diehl V, International Harmonization Project on L (2007) Revised response criteria for malignant lymphoma. J Clin Oncol 25(5):579–586. doi:10.​1200/​jco.​2006.​09.​2403 CrossRefPubMed
29.
go back to reference Keating NL, Landrum MB, Lamont EB, Bozeman SR, Krasnow SH, Shulman LN, Brown JR, Earle CC, Oh WK, Rabin M, McNeil BJ (2011) Quality of care for older patients with cancer in the Veterans Health Administration versus the private sector: a cohort study. Ann Intern Med 154(11):727–736. doi:10.7326/0003-4819-154-11-201106070-00004 CrossRefPubMed Keating NL, Landrum MB, Lamont EB, Bozeman SR, Krasnow SH, Shulman LN, Brown JR, Earle CC, Oh WK, Rabin M, McNeil BJ (2011) Quality of care for older patients with cancer in the Veterans Health Administration versus the private sector: a cohort study. Ann Intern Med 154(11):727–736. doi:10.​7326/​0003-4819-154-11-201106070-00004 CrossRefPubMed
30.
go back to reference Forsythe LP, Arora NK, Alfano CM, Weaver KE, Hamilton AS, Aziz N, Rowland JH (2014) Role of oncologists and primary care physicians in providing follow-up care to non-Hodgkin lymphoma survivors within 5 years of diagnosis: a population-based study. Support Care Cancer 22(6):1509–1517. doi:10.1007/s00520-013-2113-z Forsythe LP, Arora NK, Alfano CM, Weaver KE, Hamilton AS, Aziz N, Rowland JH (2014) Role of oncologists and primary care physicians in providing follow-up care to non-Hodgkin lymphoma survivors within 5 years of diagnosis: a population-based study. Support Care Cancer 22(6):1509–1517. doi:10.​1007/​s00520-013-2113-z
31.
go back to reference Fung CH, Lim YW, Mattke S, Damberg C, Shekelle PG (2008) Systematic review: the evidence that publishing patient care performance data improves quality of care. Ann Intern Med 148(2):111–123CrossRefPubMed Fung CH, Lim YW, Mattke S, Damberg C, Shekelle PG (2008) Systematic review: the evidence that publishing patient care performance data improves quality of care. Ann Intern Med 148(2):111–123CrossRefPubMed
33.
go back to reference Ivers N, Jamtvedt G, Flottorp S, Young JM, Odgaard-Jensen J, French SD, O'Brien MA, Johansen M, Grimshaw J, Oxman AD (2012) Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev 6, CD000259. doi:10.1002/14651858.CD000259.pub3 PubMed Ivers N, Jamtvedt G, Flottorp S, Young JM, Odgaard-Jensen J, French SD, O'Brien MA, Johansen M, Grimshaw J, Oxman AD (2012) Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev 6, CD000259. doi:10.​1002/​14651858.​CD000259.​pub3 PubMed
Metadata
Title
Trends in quality of non-Hodgkin’s lymphoma care: is it getting better?
Authors
J. J. C. Stienen
P. B. Ottevanger
L. Wennekes
S. A. M. van de Schans
H. M. Dekker
R. W. M. van der Maazen
J. H. J. M. van Krieken
N. M. A. Blijlevens
R. P. M. G. Hermens
On behalf of the PEARL study group
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 7/2015
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-015-2340-0

Other articles of this Issue 7/2015

Annals of Hematology 7/2015 Go to the issue