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Annals of Hematology
Published in: Annals of Hematology 10/2005

01-10-2005 | Letter to the Editor

Successful treatment of a patient with myelodysplastic syndrome (RAEB) with Darbepoetin-alfa in combination with Pegfilgrastim

Authors: Andreas Jakob, Friedrich W. Hirsch, Monika Engelhardt

Published in: Annals of Hematology | Issue 10/2005

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Excerpt

Dear Editor, …
Literature
1.
Casadevall N, Durieux P, Dubois S et al (2004) Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: a randomized, controlled trial. Blood 104:321–327CrossRefPubMed
2.
Hellstrom-Lindberg E, Gulbrandsen N, Lindberg G et al (2003) A validated decision model for treating the anemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life. Br J Haematol 120:1037–1046CrossRefPubMed
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Kasper C, Zahner J, Sayer HG (2002) Recombinant human erythropoietin in combined treatment with granulocyte- or granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes. J Cancer Res Clin Oncol 128:497–502
5.
Musto P, Sanpaolo G, D’Arena G et al (2001) Adding growth factors or IL-3 to erythropoietin has limited effects on anemia of transfusion-dependent patients with myelodysplastic syndromes unresponsive to erythropoietin alone. Haematologica 86:44–51PubMed
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Tehranchi R, Fadeel B, Forsblom AM et al (2003) Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors. Blood 101:1080–1086CrossRefPubMed
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Rigolin GM, Porta MD, Ciccone M et al (2004) In patients with myelodysplastic syndromes response to rhEPO and G-CSF treatment is related to an increase of cytogenetically normal CD34 cells. Br J Haematol 126:501–507CrossRefPubMed
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Cheson BD, Bennett JM, Kantarjian H et al (2000) Report of an international working group to standardize response criteria for myelodysplastic syndromes. Blood 96:3671–3674PubMed
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Musto P, Lanza F, Balleari E et al (2004) Darbepoetin alpha for the treatment of anaemia in low-intermediate risk myelodysplastic syndromes. Br J Haematol 128:204–209CrossRef
10.
Spiriti MAA, Latagliata R, Niscola P et al (2005) Impact of a new dosing regimen of epoetin alfa on quality of life an anemia in patients with low-risk myelodysplastic syndrome. Ann Hematol 84:167–176CrossRefPubMed
Metadata
Title
Successful treatment of a patient with myelodysplastic syndrome (RAEB) with Darbepoetin-alfa in combination with Pegfilgrastim
Authors
Andreas Jakob
Friedrich W. Hirsch
Monika Engelhardt
Publication date
01-10-2005
Publisher
Springer-Verlag
Published in
Annals of Hematology / Issue 10/2005
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-005-1060-2

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