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Annals of Hematology
Published in: Annals of Hematology 4/2004

01-04-2004 | Case Report

A new sarcomatoid variant of multiple myeloma in a 20-year-old male

Authors: I. C. Gauer, V. Hagen, H. Merz

Published in: Annals of Hematology | Issue 4/2004

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Abstract

We present a 20-year-old man with a rare variant of multiple myeloma with peculiar spindle cell morphology and sarcomatoid growth. The diagnosis of multiple myeloma was substantiated by clinical examinations. The patient was treated with several therapeutic trials including autologous stem cell support. Unfortunately, he developed a disseminated aspergillosis of the lungs and died of fatal lung bleeding. We recommended that "sarcomatous" multiple myeloma be considered in cases of "unclassifiable" sarcomatous tumors of the bone marrow.
Literature
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Badros A, Barlogie B, Siegel E, Roberts J, Langmaid C, Zangari M (2001) Results of autologous stem cell transplant in multiple myeloma patients with renal failure. Br J Haematol 114:822–829CrossRefPubMed
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Bartl R, Frisch B, Fateh-Moghadan A, Kettner G, Jaeger K, Sommerfeld W (1987) Histological classification and staging of multiple myeloma. Am J Clin Pathol 7:342–355
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Blade J, Kyle R.A, Greipp PR (1996) Presenting features and prognosis in 72 patients with multiple myeloma who were younger than 40 years. Br J Haematol 93:345–353PubMed
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Blade J, Kyle RA, Greipp PR (1996) Multiple myeloma in patients younger than 30 years, report of cases and review of the literature. Arch Int Med 156:1463–1468CrossRef
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Brunning RD, McKenna RW (1994) Atlas of tumor pathology: tumors of the bone marrow. Armed Forces Institute of Pathology, Bethesda, MD
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Grogan TM, Van Damp B, Kyle RA, Muller-Hermelink HK, Harris NL (2001) Plasma cell neoplasms. World Health Organization classification of tumors, pathology and genetics: tumours of hematopoietic and lymphoid tissues. IARC Press, Lyon
Metadata
Title
A new sarcomatoid variant of multiple myeloma in a 20-year-old male
Authors
I. C. Gauer
V. Hagen
H. Merz
Publication date
01-04-2004
Publisher
Springer-Verlag
Published in
Annals of Hematology / Issue 4/2004
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-003-0754-6

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