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CardioVascular and Interventional Radiology

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01-12-2018 | Laboratory Investigation

Effects of Different Mixing Agents on the Stability of Sodium Tetradecyl Sulfate (STS) Foam: An Experimental Study

Authors: Kazuki Hashimoto, MD, Barry Uchida, Masahiro Horikawa, Hidefumi Mimura, Khashayar Farsad

Published in: CardioVascular and Interventional Radiology | Issue 12/2018

Abstract

Purpose

To evaluate the effect of air, CO₂ and contrast medium-air on the dwell time (DT) stability of sodium tetradecyl sulfate (STS) foam.

Materials and Methods

Three types of foam sclerosants (air-foam, CO₂-foam, contrast-air-foam) were injected eight times into an inclined straight plastic tube (internal diameters 4 mm and 10 mm) filled with a blood substitute. Injections were captured by CCD camera, and images were transferred for digital analysis and calculation of DT.

Results

Contrast-air-foam and air-foam in a 4-mm tube showed 5.6-/3.3-fold greater DT compared to CO₂-foam, respectively (P = 0.001). Contrast-air-foam in a 10-mm tube showed 2.1-fold greater DT compared to CO₂-foam (P = 0.0167).

Conclusion

A mixture of air and iodinated contrast improves the stability of STS foam compared to mixtures using only air or CO₂. Further, animal and clinical studies are needed to validate this in vitro result.

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Title: Effects of Different Mixing Agents on the Stability of Sodium Tetradecyl Sulfate (STS) Foam: An Experimental Study
Authors: Kazuki Hashimoto, MD
Barry Uchida
Masahiro Horikawa
Hidefumi Mimura
Khashayar Farsad
Publication date: 01-12-2018
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 12/2018
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-018-2049-2

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Effects of Different Mixing Agents on the Stability of Sodium Tetradecyl Sulfate (STS) Foam: An Experimental Study

Abstract

Purpose

Materials and Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Materials and Methods

Results

Conclusion

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