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CardioVascular and Interventional Radiology
Published in: CardioVascular and Interventional Radiology 6/2016

Open Access 01-06-2016 | Clinical Investigation

Novel Software-Assisted Hemodynamic Evaluation of Pelvic Flow During Chemoperfusion of Pelvic Arteries for Bladder Cancer: Double- Versus Single-Balloon Technique

Authors: Kiyohito Yamamoto, Kazuhiro Yamamoto, Go Nakai, Haruhito Azuma, Yoshifumi Narumi

Published in: CardioVascular and Interventional Radiology | Issue 6/2016

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Abstract

Purpose

Approximately 83 % of patients with bladder cancer have achieved a complete response after undergoing a novel bladder preservation therapy involving balloon-occluded intra-arterial infusion chemotherapy (BOAI) using a four-lumen double-balloon catheter, known as the Osaka Medical College regimen. This study aimed to show the quantitative difference in hemodynamics of the bladder arteries using syngo iFlow (Siemens Healthcare, Erlangen, Germany), which provides an automatic tool for quantitative blood flow analysis between double BOAI (D-BOAI) and conventional single BOAI (S-BOAI).

Materials and Methods

Fifty patients were included. The catheters were introduced into both posterior trunks of the internal iliac arteries via contralateral femoral artery access. A side hole between the distal and proximal balloons was placed at the origin of each bladder artery to allow clear visualization of angiographic flow of the injected agent into the urinary bladder. Digital subtraction angiography was used during analysis with the syngo iFlow to evaluate the hemodynamics of the contrast medium in the pelvic arteries during BOAI. The comparative change in the amount of contrast medium in the bladder arteries between D-BOAI and S-BOAI was assessed using syngo iFlow.

Results

One-hundred pelvic sides were analyzed. The amount of contrast medium in the bladder arteries using D-BOAI was more than twice that using S-BOAI (right, 3.03-fold; left, 2.81-fold).

Conclusion

The amount of contrast medium in the bladder arteries using D-BOAI was higher than that using conventional S-BOAI. This may increase the anticancer drug concentration in the affected bladder, leading to a good clinical response.
Literature
1.
Azuma H, Kotake Y, Yamamoto K, et al. Effect of combined therapy using balloon-occluded arterial infusion of cisplatin and hemodialysis with concurrent radiation for locally invasive bladder cancer. Am J Clin Oncol. 2008;31(1):11–21.CrossRefPubMed
2.
Azuma H, Yamamoto K, Inamoto T, et al. Total cystectomy versus bladder preservation therapy for locally invasive bladder cancer: effect of combined therapy using balloon-occluded arterial infusion of anticancer agent and hemodialysis with concurrent radiation. Am J Clin Oncol. 2009;32(6):592–606.CrossRefPubMed
3.
Azuma H, Inamoto T, Takahara K, et al. Effect of a novel bladder preservation therapy, BOAI-CDDP-radiation (OMC-regimen). Int J Oncol. 2013;43(1):79–87.PubMed
4.
Azuma H, Inamoto T, Takahara K, et al. A great option for elderly patients with locally invasive bladder cancer, BOAI-CDDP-radiation (OMC regimen). Int J Oncol. 2013;43(4):1087–94.PubMed
5.
Azuma H, Inamoto T, Takahara K, et al. The novel bladder preservation therapy BOAI-CDDP-radiation (OMC-regimen): a new treatment option for invasive bladder cancer patients with lymph node metastasis. Int J Oncol. 2014;44(6):1895–903.PubMed
6.
Azuma H, Inamoto T, Takahara K, et al. Novel bladder preservation therapy with Osaka Medical College regimen. J Urol. 2015;193(2):443–50.CrossRefPubMed
7.
Azuma H, Inamoto T, Takahara K, et al. Neoadjuvant and adjuvant chemotherapy for locally advanced bladder carcinoma: development of novel bladder preservation approach, Osaka Medical College regimen. Int J Urol. 2012;19(1):26–38.CrossRefPubMed
8.
Azuma H, Inamoto T, Ibuki N, et al. Novel bladder preservation therapy for locally invasive bladder cancer: combined therapy using balloon-occluded arterial infusion of anticancer agent and hemodialysis with concurrent radiation. Int J Oncol. 2010;37(4):773–85.CrossRefPubMed
9.
Azuma H, Inamoto T, Ibuki N, et al. Utility of the novel bladder preservation therapy, BOAI-CDDP-radiation (OMC-regimen), for elderly patients with invasive bladder cancer. Int J Oncol. 2011;38(1):13–24.PubMed
10.
Strother CM, Bender F, Deuerling-Zheng Y, et al. Parametric color coding of digital subtraction angiography. AJNR Am J Neuroradiol. 2010;31(5):919–24.CrossRefPubMed
11.
Lin CJ, Hung SC, Guo WY, et al. Monitoring peri-therapeutic cerebral circulation time: a feasibility study using color-coded quantitative DSA in patients with steno-occlusive arterial disease. AJNR Am J Neuroradiol. 2012;33(9):1685–90.CrossRefPubMed
12.
Saad WE, Anderson CL, Kowarschik M, et al. Quantifying increased hepatic arterial flow with test balloon occlusion of the splenic artery in liver transplant recipients with suspected splenic steal syndrome: quantitative digitally subtracted angiography correlation with arterial Doppler parameters. Vasc Endovascular Surg. 2012;46(5):384–92.CrossRefPubMed
13.
Golitz P, Struffert T, Lucking H, et al. Parametric color coding of digital subtraction angiography in the evaluation of carotid cavernous fistulas. Clin Neuroradiol. 2013;23(2):113–20.CrossRefPubMed
14.
Zhang XB, Zhuang ZG, Ye H, et al. Objective assessment of transcatheter arterial chemoembolization angiographic endpoints: preliminary study of quantitative digital subtraction angiography. J Vasc Interv Radiol JVIR. 2013;24(5):667–71.CrossRefPubMed
Metadata
Title
Novel Software-Assisted Hemodynamic Evaluation of Pelvic Flow During Chemoperfusion of Pelvic Arteries for Bladder Cancer: Double- Versus Single-Balloon Technique
Authors
Kiyohito Yamamoto
Kazuhiro Yamamoto
Go Nakai
Haruhito Azuma
Yoshifumi Narumi
Publication date
01-06-2016
Publisher
Springer US
Published in
CardioVascular and Interventional Radiology / Issue 6/2016
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-016-1296-3

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