Skip to main content
Top
Published in: CardioVascular and Interventional Radiology 3/2014

01-06-2014 | Clinical Investigation

Outcome Study of Real-time MR-guided Cervical Periradicular Injection Therapy in an Open 1.0 Tesla MRI System

Authors: Martin H. Maurer, Alexander C. Disch, Tony Hartwig, Diane M. Renz, Nils Schreiter, B. Hamm, Florian Streitparth

Published in: CardioVascular and Interventional Radiology | Issue 3/2014

Login to get access

Abstract

Purpose

To evaluate the accuracy, safety, and efficacy of cervical nerve root injection therapy using magnetic resonance guidance in an open 1.0 T MRI system.

Methods

Between September 2009 and April 2012, a total of 21 patients (9 men, 12 women; mean age 47.1 ± 11.1 years) underwent MR-guided cervical periradicular injection for cervical radicular pain in an open 1.0 T system. An interactive proton density-weighted turbo spin echo (PDw TSE) sequence was used for real-time guidance of the MR-compatible 20-gauge injection needle. Clinical outcome was evaluated on a verbal numeric rating scale (VNRS) before injection therapy (baseline) and at 1 week and 1, 3, and 6 months during follow-up.

Results

All procedures were technically successful and there were no major complications. The mean preinterventional VNRS score was 7.42 and exhibited a statistically significant decrease (P < 0.001) at all follow-up time points: 3.86 ± 1.53 at 1 week, 3.21 ± 2.19 at 1 month, 2.58 ± 2.54 at 3 months, and 2.76 ± 2.63 at 6 months. At 6 months, 14.3 % of the patients reported complete resolution of radicular pain and 38.1 % each had either significant (4–8 VNRS score points) or mild (1–3 VNRS score points) relief of pain; 9.5 % experienced no pain relief.

Conclusion

Magnetic resonance fluoroscopy-guided periradicular cervical spine injection is an accurate, safe, and efficacious treatment option for patients with cervical radicular pain. The technique may be a promising alternative to fluoroscopy- or CT-guided injections of the cervical spine, especially in young patients and in patients requiring repeat injections.
Literature
1.
go back to reference Martin BI, Deyo RA, Mirza SK et al (2008) Expenditures and health status among adults with back and neck problems. JAMA 299:656–664PubMedCrossRef Martin BI, Deyo RA, Mirza SK et al (2008) Expenditures and health status among adults with back and neck problems. JAMA 299:656–664PubMedCrossRef
2.
go back to reference Kolstad F, Leivseth G, Nygaard OP (2005) Transforaminal steroid injections in the treatment of cervical radiculopathy. A prospective outcome study. Acta Neurochir 147:1065–1070PubMedCrossRef Kolstad F, Leivseth G, Nygaard OP (2005) Transforaminal steroid injections in the treatment of cervical radiculopathy. A prospective outcome study. Acta Neurochir 147:1065–1070PubMedCrossRef
3.
go back to reference Bush K, Hillier S (1996) Outcome of cervical radiculopathy treated with periradicular/epidural corticosteroid injections: a prospective study with independent clinical review. Eur Spine J 5:319–325PubMedCrossRef Bush K, Hillier S (1996) Outcome of cervical radiculopathy treated with periradicular/epidural corticosteroid injections: a prospective study with independent clinical review. Eur Spine J 5:319–325PubMedCrossRef
4.
go back to reference Vallee JN, Feydy A, Carlier RY (2001) Chronic cervical radiculopathy: lateral-approach periradicular corticosteroid injection. Radiology 218:886–892PubMedCrossRef Vallee JN, Feydy A, Carlier RY (2001) Chronic cervical radiculopathy: lateral-approach periradicular corticosteroid injection. Radiology 218:886–892PubMedCrossRef
5.
go back to reference Schellhas KP, Pollei SR, Johnson BA (2007) Selective cervical nerve root blockade: experience with a safe and reliable technique using an anterolateral approach for needle placement. AJNR Am J Neuroradiol 28:1909–1914PubMedCrossRef Schellhas KP, Pollei SR, Johnson BA (2007) Selective cervical nerve root blockade: experience with a safe and reliable technique using an anterolateral approach for needle placement. AJNR Am J Neuroradiol 28:1909–1914PubMedCrossRef
6.
go back to reference Paulson EK, Sheafor DH, Enterline DS (2001) CT fluoroscopy-guided interventional procedures: techniques and radiation dose to radiologists. Radiology 220:161–167PubMedCrossRef Paulson EK, Sheafor DH, Enterline DS (2001) CT fluoroscopy-guided interventional procedures: techniques and radiation dose to radiologists. Radiology 220:161–167PubMedCrossRef
7.
go back to reference Brenner DJ, Hall EJ (2007) Computed tomography—an increasing source of radiation exposure. N Engl J Med 357:2277–2284PubMedCrossRef Brenner DJ, Hall EJ (2007) Computed tomography—an increasing source of radiation exposure. N Engl J Med 357:2277–2284PubMedCrossRef
8.
go back to reference Streitparth F, Walter T, Wonneberger U et al (2010) Image-guided spinal injection procedures in open highfield MRI with vertical field orientation: feasibility and technical features. Eur Radiol 20:395–403PubMedCrossRef Streitparth F, Walter T, Wonneberger U et al (2010) Image-guided spinal injection procedures in open highfield MRI with vertical field orientation: feasibility and technical features. Eur Radiol 20:395–403PubMedCrossRef
9.
go back to reference Sequeiros RB, Ojala RO, Klemola R et al (2002) MRI-guided periradicular nerve root infiltration therapy in low-field (0.23-T) MRI system using optical instrument tracking. Eur Radiol 12:1331–1337PubMedCrossRef Sequeiros RB, Ojala RO, Klemola R et al (2002) MRI-guided periradicular nerve root infiltration therapy in low-field (0.23-T) MRI system using optical instrument tracking. Eur Radiol 12:1331–1337PubMedCrossRef
10.
go back to reference Fritz J, Thomas C, Clasen S et al (2009) Freehand real-time MRI-guided lumbar spinal injection procedures at 1.5 T: feasibility, accuracy, and safety. AJR Am J Roentgenol 192:W161–W167PubMedCrossRef Fritz J, Thomas C, Clasen S et al (2009) Freehand real-time MRI-guided lumbar spinal injection procedures at 1.5 T: feasibility, accuracy, and safety. AJR Am J Roentgenol 192:W161–W167PubMedCrossRef
11.
go back to reference Streitparth F, De Bucourt M, Hartwig T et al (2013) Real-time MR-guided lumbosacral periradicular injection therapy using an open 1.0-T MRI system: an outcome study. Invest Radiol 48:471–476PubMedCrossRef Streitparth F, De Bucourt M, Hartwig T et al (2013) Real-time MR-guided lumbosacral periradicular injection therapy using an open 1.0-T MRI system: an outcome study. Invest Radiol 48:471–476PubMedCrossRef
12.
go back to reference Bangard C, Paszek J, Berg F et al (2007) MR imaging of claustrophobic patients in an open 1.0 T scanner: motion artifacts and patient acceptability compared with closed bore magnets. Eur J Radiol 64:152–157PubMedCrossRef Bangard C, Paszek J, Berg F et al (2007) MR imaging of claustrophobic patients in an open 1.0 T scanner: motion artifacts and patient acceptability compared with closed bore magnets. Eur J Radiol 64:152–157PubMedCrossRef
13.
go back to reference Razzaq AA, O’Brien D, Mathew B et al (2007) Efficacy and durability of fluoroscopically guided cervical nerve root block. Br J Neurosurg 21:365–369PubMedCrossRef Razzaq AA, O’Brien D, Mathew B et al (2007) Efficacy and durability of fluoroscopically guided cervical nerve root block. Br J Neurosurg 21:365–369PubMedCrossRef
14.
go back to reference Jee H, Lee JH, Kim J et al (2013) Ultrasound-guided selective nerve root block versus fluoroscopy-guided transforaminal block for the treatment of radicular pain in the lower cervical spine: a randomized, blinded, controlled study. Skeletal Radiol 42:69–78PubMedCrossRef Jee H, Lee JH, Kim J et al (2013) Ultrasound-guided selective nerve root block versus fluoroscopy-guided transforaminal block for the treatment of radicular pain in the lower cervical spine: a randomized, blinded, controlled study. Skeletal Radiol 42:69–78PubMedCrossRef
15.
go back to reference Kanal E, Barkovich AJ, Bell C et al (2013) ACR guidance document on MR safe practices: 2013. J Magn Reson Imaging 37:501–530PubMedCrossRef Kanal E, Barkovich AJ, Bell C et al (2013) ACR guidance document on MR safe practices: 2013. J Magn Reson Imaging 37:501–530PubMedCrossRef
16.
go back to reference Chung JY, Yim JH, Seo HY et al (2012) The efficacy and persistence of selective nerve root block under fluoroscopic guidance for cervical radiculopathy. Asian Spine J 6:227–232PubMedCentralPubMedCrossRef Chung JY, Yim JH, Seo HY et al (2012) The efficacy and persistence of selective nerve root block under fluoroscopic guidance for cervical radiculopathy. Asian Spine J 6:227–232PubMedCentralPubMedCrossRef
17.
go back to reference Wolter T, Knoeller S, Berlis A, Hader C (2010) CT-guided cervical selective nerve root block with a dorsal approach. AJNR Am J Neuroradiol 31:1831–1836PubMedCrossRef Wolter T, Knoeller S, Berlis A, Hader C (2010) CT-guided cervical selective nerve root block with a dorsal approach. AJNR Am J Neuroradiol 31:1831–1836PubMedCrossRef
18.
go back to reference Brouwers PJ, Kottink EJ, Simon MA, Prevo RL (2001) A cervical anterior spinal artery syndrome after diagnostic blockade of the right C6-nerve root. Pain 91:397–399PubMedCrossRef Brouwers PJ, Kottink EJ, Simon MA, Prevo RL (2001) A cervical anterior spinal artery syndrome after diagnostic blockade of the right C6-nerve root. Pain 91:397–399PubMedCrossRef
19.
go back to reference Tiso RL, Cutler T, Catania JA, Whalen K (2004) Adverse central nervous system sequelae after selective transforaminal block: the role of corticosteroids. Spine J 4:468–474PubMedCrossRef Tiso RL, Cutler T, Catania JA, Whalen K (2004) Adverse central nervous system sequelae after selective transforaminal block: the role of corticosteroids. Spine J 4:468–474PubMedCrossRef
20.
go back to reference Rozin L, Rozin R, Koehler SA, Shakir A et al (2003) Death during transforaminal epidural steroid nerve root block (C7) due to perforation of the left vertebral artery. Am J Forensic Med Pathol 24:351–355PubMedCrossRef Rozin L, Rozin R, Koehler SA, Shakir A et al (2003) Death during transforaminal epidural steroid nerve root block (C7) due to perforation of the left vertebral artery. Am J Forensic Med Pathol 24:351–355PubMedCrossRef
21.
go back to reference Ziai WC, Ardelt AA, Llinas RH (2006) Brainstem stroke following uncomplicated cervical epidural steroid injection. Arch Neuroradiol 63:1643–1646 Ziai WC, Ardelt AA, Llinas RH (2006) Brainstem stroke following uncomplicated cervical epidural steroid injection. Arch Neuroradiol 63:1643–1646
22.
go back to reference Scanlon GC, Moeller-Bertram T, Romanowsky SM, Wallace MS (2007) Cervical transforaminal epidural steroid injections: more dangerous than we think? Spine 32:1249–1256PubMedCrossRef Scanlon GC, Moeller-Bertram T, Romanowsky SM, Wallace MS (2007) Cervical transforaminal epidural steroid injections: more dangerous than we think? Spine 32:1249–1256PubMedCrossRef
23.
go back to reference Wolter T, Mohadjer M, Berlis A, Knoeller S (2009) Cervical CT-guided, selective nerve root blocks: improved safety by dorsal approach. AJNR Am J Neuroradiol 30:336–337PubMedCrossRef Wolter T, Mohadjer M, Berlis A, Knoeller S (2009) Cervical CT-guided, selective nerve root blocks: improved safety by dorsal approach. AJNR Am J Neuroradiol 30:336–337PubMedCrossRef
24.
go back to reference Ma DJ, Gilula LA, Riew KD (2005) Complications of fluoroscopically guided extraforaminal cervical nerve blocks. An analysis of 1036 injections. J Bone Joint Surg Am 87:1025–1030PubMedCrossRef Ma DJ, Gilula LA, Riew KD (2005) Complications of fluoroscopically guided extraforaminal cervical nerve blocks. An analysis of 1036 injections. J Bone Joint Surg Am 87:1025–1030PubMedCrossRef
25.
go back to reference Crall TS, Gilula LA, Kim YJ et al (2006) The diagnostic effect of various needle tip positions in selective lumbar nerve blocks: an analysis of 1202 injections. Spine 31:920–922PubMedCrossRef Crall TS, Gilula LA, Kim YJ et al (2006) The diagnostic effect of various needle tip positions in selective lumbar nerve blocks: an analysis of 1202 injections. Spine 31:920–922PubMedCrossRef
26.
go back to reference Nawfel RD, Judy PF, Silverman SG et al (2000) Patient and personnel exposure during CT fluoroscopy-guided interventional procedures. Radiology 216:180–184PubMedCrossRef Nawfel RD, Judy PF, Silverman SG et al (2000) Patient and personnel exposure during CT fluoroscopy-guided interventional procedures. Radiology 216:180–184PubMedCrossRef
27.
28.
go back to reference Schmid G, Schmitz A, Borchardt D et al (2006) Effective dose of CT- and fluoroscopy-guided perineural/epidural injections of the lumbar spine: a comparative study. Cardiovasc Intervent Radiol 29:84–91PubMedCrossRef Schmid G, Schmitz A, Borchardt D et al (2006) Effective dose of CT- and fluoroscopy-guided perineural/epidural injections of the lumbar spine: a comparative study. Cardiovasc Intervent Radiol 29:84–91PubMedCrossRef
29.
go back to reference Hoang JK, Yoshizumi TT, Toncheva G et al (2011) Radiation dose exposure for lumbar spine epidural steroid injections: a comparison of conventional fluoroscopy data and CT fluoroscopy techniques. AJR Am J Roentgenol 197:778–792PubMedCrossRef Hoang JK, Yoshizumi TT, Toncheva G et al (2011) Radiation dose exposure for lumbar spine epidural steroid injections: a comparison of conventional fluoroscopy data and CT fluoroscopy techniques. AJR Am J Roentgenol 197:778–792PubMedCrossRef
30.
go back to reference Deli M, Fritz J, Mateiescu S et al (2013) Saline as the sole contrast agent for successful MRI-guided epidural injections. Cardiovasc Intervent Radiol 36:748–755PubMedCrossRef Deli M, Fritz J, Mateiescu S et al (2013) Saline as the sole contrast agent for successful MRI-guided epidural injections. Cardiovasc Intervent Radiol 36:748–755PubMedCrossRef
31.
go back to reference Moche M, Zajonz D, Kahn T, Busse H (2010) MRI-guided procedures in various regions of the body using a robotic assistance system in a closed-bore scanner: preliminary clinical experience and limitations. J Magn Reson Imaging 31:964–974PubMedCrossRef Moche M, Zajonz D, Kahn T, Busse H (2010) MRI-guided procedures in various regions of the body using a robotic assistance system in a closed-bore scanner: preliminary clinical experience and limitations. J Magn Reson Imaging 31:964–974PubMedCrossRef
32.
go back to reference Fritz J, U-Thainual P, Ungi T et al (2013) Augmented reality visualisation using an image overlay system for MR-guided interventions: technical performance of spine injection procedures in human cadavers at 1.5 Tesla. Eur Radiol 23:235–245PubMedCrossRef Fritz J, U-Thainual P, Ungi T et al (2013) Augmented reality visualisation using an image overlay system for MR-guided interventions: technical performance of spine injection procedures in human cadavers at 1.5 Tesla. Eur Radiol 23:235–245PubMedCrossRef
33.
go back to reference Maurer MH, Schreiter N, de Bucourt M et al (2013) Cost comparison of nerve root infiltration of the lumbar spine under MRI and CT guidance. Eur Radiol 23:1487–1494PubMedCrossRef Maurer MH, Schreiter N, de Bucourt M et al (2013) Cost comparison of nerve root infiltration of the lumbar spine under MRI and CT guidance. Eur Radiol 23:1487–1494PubMedCrossRef
Metadata
Title
Outcome Study of Real-time MR-guided Cervical Periradicular Injection Therapy in an Open 1.0 Tesla MRI System
Authors
Martin H. Maurer
Alexander C. Disch
Tony Hartwig
Diane M. Renz
Nils Schreiter
B. Hamm
Florian Streitparth
Publication date
01-06-2014
Publisher
Springer US
Published in
CardioVascular and Interventional Radiology / Issue 3/2014
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-013-0738-4

Other articles of this Issue 3/2014

CardioVascular and Interventional Radiology 3/2014 Go to the issue