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CardioVascular and Interventional Radiology
Published in: CardioVascular and Interventional Radiology 3/2013

01-06-2013 | Clinical Investigation

Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections

Authors: Martin Deli, Jan Fritz, Serban Mateiescu, Martin Busch, John A. Carrino, Jan Becker, Marietta Garmer, Dietrich Grönemeyer

Published in: CardioVascular and Interventional Radiology | Issue 3/2013

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Abstract

Purpose

To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T.

Methods

A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications.

Results

105 MRI-guided epidural injections (12 of 105 with gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 ± 9 min in the gadolinium-enhanced saline solution group and 22 ± 8 min in the saline solution group (p = 0.75).

Conclusion

Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.
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Metadata
Title
Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections
Authors
Martin Deli
Jan Fritz
Serban Mateiescu
Martin Busch
John A. Carrino
Jan Becker
Marietta Garmer
Dietrich Grönemeyer
Publication date
01-06-2013
Publisher
Springer-Verlag
Published in
CardioVascular and Interventional Radiology / Issue 3/2013
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-012-0489-7

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