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Published in: World Journal of Surgery 5/2020

Open Access 01-05-2020 | Surgery in Low and Middle Income Countries

Reducing Gastroschisis Mortality: A Quality Improvement Initiative at a Ugandan Pediatric Surgery Unit

Authors: A. Wesonga, M. Situma, K. Lakhoo

Published in: World Journal of Surgery | Issue 5/2020

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Abstract

Introduction

With modern treatment, survival of gastroschisis exceeds 90% in high-income countries. Survival in these countries has been largely attributed to prenatal diagnosis, delivery at tertiary facilities with timely resuscitation, timely intervention, parenteral nutrition and intensive care facilities. In sub-Saharan Africa, due to lack of these facilities, mortality rates are still alarmingly high ranging from 75 to 100%. In Uganda the mortality is 98%.

Aim

The aim of this study was to reduce gastroschisis mortality in a feasible, sustainable way using a locally derived gastroschisis care protocol at a referring hospital in Western Uganda.

Methods

Data collection was performed from January to October 2018. Nursing staff were interviewed regarding the survival and management of gastroschisis babies. A locally derived protocol was created with staff input and commitment from all the team members.

Results

Four mothers absconded and 17 babies were cared for using the newly designed protocol. Seven survived and were well at one month post discharge follow-up, reducing the mortality for this condition from 98 to 59%.

Conclusion

A dedicated team with minimal resources can significantly reduce the mortality in gastroschisis by almost 40% using a locally derived protocol.
Literature
1.
go back to reference Kilby MD (2006) The incidence of gastroschisis: is increasing in the UK, particularly among babies of young mothers. BMJ 332:250–251CrossRef Kilby MD (2006) The incidence of gastroschisis: is increasing in the UK, particularly among babies of young mothers. BMJ 332:250–251CrossRef
2.
go back to reference DriverC BruceJ, Bianchi A et al (2000) The contemporary outcome of gastroschisis. J Pediatr Surg 35:1719–1723CrossRef DriverC BruceJ, Bianchi A et al (2000) The contemporary outcome of gastroschisis. J Pediatr Surg 35:1719–1723CrossRef
4.
go back to reference Feldkamp ML, Botto LD, Byrne JL et al (2016) Clinical presentation and survival in a population-based cohort of infants with gastroschisis in Utah, 1997–2011. Am J Med Genet A 170:306–315CrossRef Feldkamp ML, Botto LD, Byrne JL et al (2016) Clinical presentation and survival in a population-based cohort of infants with gastroschisis in Utah, 1997–2011. Am J Med Genet A 170:306–315CrossRef
5.
go back to reference Ameh EA, Chirdan LB (2000) Ruptured exomphalos and gastroschisis: a retrospective analysis of morbidity and mortality in Nigerian children. Pediatr Surg Int 16:23–25CrossRef Ameh EA, Chirdan LB (2000) Ruptured exomphalos and gastroschisis: a retrospective analysis of morbidity and mortality in Nigerian children. Pediatr Surg Int 16:23–25CrossRef
6.
go back to reference Wesonga AS, Fitzgerald TN, Kabuye R et al (2016) Gastroschisis in Uganda: opportunities for improved survival. J Pediatr Surg 51:1772–1777CrossRef Wesonga AS, Fitzgerald TN, Kabuye R et al (2016) Gastroschisis in Uganda: opportunities for improved survival. J Pediatr Surg 51:1772–1777CrossRef
7.
go back to reference BradnockTJ Marven S, Owen A et al (2011) Gastroschisis: one year outcomes from national cohort study. BMJ 343:d6749CrossRef BradnockTJ Marven S, Owen A et al (2011) Gastroschisis: one year outcomes from national cohort study. BMJ 343:d6749CrossRef
9.
go back to reference Bickler S, Kyambi J, Rode H (2001) Pediatric surgery in sub-Saharan Africa. Pediatr Surg Int 17:442–447CrossRef Bickler S, Kyambi J, Rode H (2001) Pediatric surgery in sub-Saharan Africa. Pediatr Surg Int 17:442–447CrossRef
10.
go back to reference Stevens P, Muller E, Becker P (2016) Gastroschisis in a developing country: poor resuscitation is a more significant predictor of mortality than postnatal transfer time. S Afr J Surg 54:4–9PubMed Stevens P, Muller E, Becker P (2016) Gastroschisis in a developing country: poor resuscitation is a more significant predictor of mortality than postnatal transfer time. S Afr J Surg 54:4–9PubMed
11.
go back to reference Apfeld JC, WrenSM Macheka N et al (2015) Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe. Surgery 158:1475–1480CrossRef Apfeld JC, WrenSM Macheka N et al (2015) Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe. Surgery 158:1475–1480CrossRef
Metadata
Title
Reducing Gastroschisis Mortality: A Quality Improvement Initiative at a Ugandan Pediatric Surgery Unit
Authors
A. Wesonga
M. Situma
K. Lakhoo
Publication date
01-05-2020
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 5/2020
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-020-05373-w

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