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World Journal of Surgery
Published in: World Journal of Surgery 8/2018

Open Access 01-08-2018 | Original Scientific Report

Validation of the Japanese Version of the Low Anterior Resection Syndrome Score

Authors: Emi Akizuki, Hiroshi Matsuno, Tetsuta Satoyoshi, Masayuki Ishii, Akihiro Usui, Tomomi Ueki, Toshihiko Nishidate, Kenji Okita, Tsunekazu Mizushima, Masaki Mori, Ichiro Takemasa

Published in: World Journal of Surgery | Issue 8/2018

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Abstract

Background

The low anterior resection syndrome (LARS) score is a patient-reported outcome measure to evaluate the severity of bowel dysfunction after rectal cancer surgery by scoring the major symptoms of LARS. The aim of this study was to translate the English version of the LARS score into Japanese and to investigate the validity and reliability of the LARS score.

Methods

The LARS score was translated in Japanese following current international recommendations. A total of 149 rectal cancer patients completed the LARS score questionnaire and were also asked a single question assessing the impact of bowel function on quality of life (QoL). A total of 136 patients answered the LARS score questionnaire twice.

Results

The Japanese LARS score showed high convergent validity, based on its good correlation between the LARS score and QoL (p < 0.001). The LARS score was able to discriminate between patients according to the tumor distance to anal verge (p < 0.001), type of surgery (p < 0.001), and time since surgery (p = 0.001). Patients after ultra-low anterior resection and intersphincteric resection showed especially high scores. The score also had high test–retest reliability (intraclass correlation coefficient: 0.87).

Conclusion

The Japanese LARS score is a valid and reliable tool for measuring LARS. The LARS score is appropriate for assessments in postoperative bowel function and international comparison. Using this score, patient-reported outcome measures of LARS in Japanese patients can be shared internationally. Additional validation reports from non-English speaking countries can support the LARS score as a worldwide assessment tool for postoperative bowel dysfunction.
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Metadata
Title
Validation of the Japanese Version of the Low Anterior Resection Syndrome Score
Authors
Emi Akizuki
Hiroshi Matsuno
Tetsuta Satoyoshi
Masayuki Ishii
Akihiro Usui
Tomomi Ueki
Toshihiko Nishidate
Kenji Okita
Tsunekazu Mizushima
Masaki Mori
Ichiro Takemasa
Publication date
01-08-2018
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 8/2018
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-018-4519-8

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