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Published in:

01-10-2006

Intersphincteric Resection in Patients with Very Low Rectal Cancer: A Review of the Japanese Experience

Authors: Norio Saito, M.D., Yoshihiro Moriya, M.D., Kazuo Shirouzu, M.D., Koutarou Maeda, M.D., Hidetaka Mochizuki, M.D., Keiji Koda, M.D., Takashi Hirai, M.D., Masanori Sugito, M.D., Masaaki Ito, M.D., Akihiro Kobayashi, M.D.

Published in: Diseases of the Colon & Rectum | Special Issue 1/2006

Purpose

This study was designed to evaluate the feasibility and oncologic and functional outcomes of intersphincteric resection for very low rectal cancer.

Methods

A feasibility study was performed using 213 specimens from abdominoperineal resections of rectal cancer. Oncologic and functional outcomes were investigated in 228 patients with rectal cancer located <5 cm from the anal verge who underwent intersphincteric resection at seven institutions in Japan between 1995 and 2004.

Results

Curative operations were accomplished by intersphincteric resection in 86 percent of patients who underwent abdominoperineal resection. Complete microscopic curative surgery was achieved by intersphincteric resection in 225 of 228 patients. Morbidity was 24 percent, and mortality was 0.4 percent. During the median observation time of 41 months, rate of local recurrence was 5.8 percent at three years, and five-year overall and disease-free survival rates were 91.9 percent and 83.2 percent, respectively. In 181 patients who received stoma closure, 68 percent displayed good continence, and only 7 percent showed worsened continence at 24 months after stoma closure. Patients with total intersphincteric resection displayed significantly worse continence than patients with partial or subtotal resection.

Conclusions

Curability with intersphincteric resection was verified histologically, and acceptable oncologic and functional outcomes were obtained by using these procedures in patients with very low rectal cancer. However, information on potential functional adverse effects after intersphincteric resection should be provided to patients preoperatively.

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Title: Intersphincteric Resection in Patients with Very Low Rectal Cancer: A Review of the Japanese Experience
Authors: Norio Saito, M.D.
Yoshihiro Moriya, M.D.
Kazuo Shirouzu, M.D.
Koutarou Maeda, M.D.
Hidetaka Mochizuki, M.D.
Keiji Koda, M.D.
Takashi Hirai, M.D.
Masanori Sugito, M.D.
Masaaki Ito, M.D.
Akihiro Kobayashi, M.D.
Publication date: 01-10-2006
Publisher: Springer-Verlag
Published in: Diseases of the Colon & Rectum / Issue Special Issue 1/2006
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI: https://doi.org/10.1007/s10350-006-0598-y

ACC 2024 Congress

Springer Medicine

Intersphincteric Resection in Patients with Very Low Rectal Cancer: A Review of the Japanese Experience

Purpose

Methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Purpose

Methods

Results

Conclusions

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