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01-08-2016 | Original Scientific Report

Perioperative Blood Transfusion is Associated with an Increased Mortality in Older Surgical Patients

Authors: Cristina Roque-Castellano, Joaquín Marchena-Gómez, Roberto Fariña-Castro, María Asunción Acosta-Mérida, María Desirée Armas-Ojeda, María Isabel Sánchez-Guédez

Published in: World Journal of Surgery | Issue 8/2016

Abstract

Background

More surgical interventions are being performed on octogenarian patients. The aim of this study was to identify factors associated with operative mortality and to determine if perioperative transfusions could affect mortality outcomes in a nonselected series of octogenarian patients undergoing surgery.

Methods

A descriptive cross-sectional study was performed on a population of 413 consecutive patients over 80 years old, treated surgically, and divided into two groups: transfused and nontransfused patients. The following variables were recorded: sociodemographic characteristics, main diagnoses, surgical procedure and its characteristics, ASA score, Charlson comorbidity index (CCI), National Nosocomial Infection Surveillance (NNIS) index, transfusion requirements, the Clavien-Dindo classification of surgical complications, and operative mortality.

Results

The mean age of the patients was 84.5 years (SD + 3.6). Transfused (25.2 %) and nontransfused patients had similar characteristics; except for neoplasia (P <0.001), NNIS (P = 0.008), operative mortality (P = 0.004), and complications according to Clavien-Dindo score (P <0.001). Operative mortality was 20.1 % (83 patients). The predictive variables associated with operative mortality were ASA score (P <0.001), emergency surgery (P <0.001), and blood transfusion (P = 0.004). After adjusting for the variables age, ASA class, NNIS, emergency surgery, and neoplasia, the multivariate analysis showed that the perioperative transfusion in octogenarian patients continued to be significantly associated with operative mortality (P = 0.019; OR 1.97, 95 % CI 1.12–3.47).

Conclusion

Perioperative transfusion is an independent predictor of postoperative mortality in surgical octogenarian patients.

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Title: Perioperative Blood Transfusion is Associated with an Increased Mortality in Older Surgical Patients
Authors: Cristina Roque-Castellano
Joaquín Marchena-Gómez
Roberto Fariña-Castro
María Asunción Acosta-Mérida
María Desirée Armas-Ojeda
María Isabel Sánchez-Guédez
Publication date: 01-08-2016
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 8/2016
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-016-3521-2

At a glance: The STEP trials

Springer Medicine

Perioperative Blood Transfusion is Associated with an Increased Mortality in Older Surgical Patients

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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