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International Orthopaedics

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01-06-2021 | Antibiotic | Original Paper

The vancomycin soaking technique: no differences in autograft re-rupture rate. A comparative study

Authors: Daniel Pérez-Prieto, Simone Perelli, Ferran Corcoll, Gonzalo Rojas, Verónica Montiel, Juan Carlos Monllau

Published in: International Orthopaedics | Issue 6/2021

Abstract

Purpose

The main aim of this study was to evaluate the re-rupture risk after an anterior cruciate ligament reconstruction (ACL-R) using the vancomycin soaking technique and to compare it with the re-rupture risk in patients on whom this technique was not utilized. The secondary purpose was to compare the functional outcomes of those two subsets of patients operated on for ACL-R.

The hypotheses are that the vancomycin soaking technique does not affect the re-rupture risk or the functional outcomes.

Material and methods

A retrospective historical cohort study was conducted. Two groups were compared in terms of the re-rupture rate (traumatic or atraumatic) and functional outcomes (International Knee Documentation Committee (IKDC), Tegner, and Lysholm). Group 1 consisted of patients that received pre-operative IV antibiotics. In group 2, the patients received pre-operative IV antibiotics along with a graft that had been presoaked in a vancomycin solution. A minimum follow-up of five years was required.

Results

There were 17 patients that suffered a re-rupture in group 1 (4.7%) and 15 in group 2 (3.9%) (n.s.). IKDC was 82.0 in group 1 and 83.9 in group 2 (p = 0.049); Tegner scored 4 in both groups (n.s.) and Lysholm was 90.3 in group 1 and 92.0 in group 2 (p = 0.015).

Conclusion

The vancomycin soaking technique for ACL autografts is a safe procedure for the daily clinical practice, in terms of re-ruptures. Moreover, it does not impair functional outcomes after an ACL-R.

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Title: The vancomycin soaking technique: no differences in autograft re-rupture rate. A comparative study
Authors: Daniel Pérez-Prieto
Simone Perelli
Ferran Corcoll
Gonzalo Rojas
Verónica Montiel
Juan Carlos Monllau
Publication date: 01-06-2021
Publisher: Springer Berlin Heidelberg
Keywords: Antibiotic
Vancomycin
Published in: International Orthopaedics / Issue 6/2021
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI: https://doi.org/10.1007/s00264-020-04805-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The vancomycin soaking technique: no differences in autograft re-rupture rate. A comparative study

Abstract

Purpose

Material and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Material and methods

Results

Conclusion

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