Published in:
Open Access
01-02-2019 | Original Paper
Bone combined cement grafting in giant cell tumor around the knee reduces mechanical failure
Authors:
Wangsiyuan Teng, Peng Lin, Yong Li, Xiaobo Yan, Hengyuan Li, Binghao Li, Zhan Wang, Yan Wu, Shengdong Wang, Xingzhi Zhou, Zenan Wang, Zhaoming Ye
Published in:
International Orthopaedics
|
Issue 2/2019
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Abstract
Objectives
The aims of our study are (1) to explore the risk factors of mechanical failure (MF), (2) to figure out an index to evaluate this risk, and (3) to select an optimal reconstruction strategy to reduce this risk.
Methods
We retrospectively reviewed 104 patients from Dec. 2008 to Mar. 2016, undergone extensive knee curettages in our institution. Radiographs and post-operative interviews were used to classified cases of MF. Relative factors (age, tumor location, the invaded area, etc.) were also collected and analyzed by SPSS software.
Results
Thick subchondral bony layer (p = 0.006) and combined grafting of the cement and bone (p = 0.006) had lower risk of mechanical failure. Mechanical failure appeared to happen in the femur (p = 0.012) more easily. The ROC curve (AUC = 0.722) reveals that less post-operative bony layer (≤ 3.3 mm) is more likely to cause mechanical failure. The Kaplan-Meier survival curve showing increased survival in those patients after a combination grafting surgery (HR, 3.799; p = 0.006).
Conclusion
Based on our study results, combined grafting of the cement and bone reduced the risk of mechanical failure in the knee due to the thin subchondral bone layer (SCB), especially in the femur.