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Published in: International Orthopaedics 2/2019

Open Access 01-02-2019 | Original Paper

Bone combined cement grafting in giant cell tumor around the knee reduces mechanical failure

Authors: Wangsiyuan Teng, Peng Lin, Yong Li, Xiaobo Yan, Hengyuan Li, Binghao Li, Zhan Wang, Yan Wu, Shengdong Wang, Xingzhi Zhou, Zenan Wang, Zhaoming Ye

Published in: International Orthopaedics | Issue 2/2019

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Abstract

Objectives

The aims of our study are (1) to explore the risk factors of mechanical failure (MF), (2) to figure out an index to evaluate this risk, and (3) to select an optimal reconstruction strategy to reduce this risk.

Methods

We retrospectively reviewed 104 patients from Dec. 2008 to Mar. 2016, undergone extensive knee curettages in our institution. Radiographs and post-operative interviews were used to classified cases of MF. Relative factors (age, tumor location, the invaded area, etc.) were also collected and analyzed by SPSS software.

Results

Thick subchondral bony layer (p = 0.006) and combined grafting of the cement and bone (p = 0.006) had lower risk of mechanical failure. Mechanical failure appeared to happen in the femur (p = 0.012) more easily. The ROC curve (AUC = 0.722) reveals that less post-operative bony layer (≤ 3.3 mm) is more likely to cause mechanical failure. The Kaplan-Meier survival curve showing increased survival in those patients after a combination grafting surgery (HR, 3.799; p = 0.006).

Conclusion

Based on our study results, combined grafting of the cement and bone reduced the risk of mechanical failure in the knee due to the thin subchondral bone layer (SCB), especially in the femur.
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Metadata
Title
Bone combined cement grafting in giant cell tumor around the knee reduces mechanical failure
Authors
Wangsiyuan Teng
Peng Lin
Yong Li
Xiaobo Yan
Hengyuan Li
Binghao Li
Zhan Wang
Yan Wu
Shengdong Wang
Xingzhi Zhou
Zenan Wang
Zhaoming Ye
Publication date
01-02-2019
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 2/2019
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-018-3939-2

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