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Published in: International Orthopaedics 5/2014

01-05-2014 | Original Paper

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Authors: Mohamed Ahmed Mashhour, Mohamed Abdel Rahman

Published in: International Orthopaedics | Issue 5/2014

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Abstract

Purpose

Various methods for the treatment of chondroblastoma of bone have been used including simple curettage, or combined with bone grafting, in addition to the use of adjuvant therapy. However, local recurrence still represents a challenge in the management of this aggressive tumour. This study focuses on evaluating the role of intraregional extended curettage together with the use of adjuvant cryotherapy and autogenous bone grafting in the treatment of benign chondroblastoma of bone aiming to decrease the recurrence rate.

Methods

All patients with chondroblastoma included in this study underwent intralesional extended curettage, adjuvant cryotherapy using liquid nitrogen, and autogenous iliac crest bone grafting. Follow up for healing of chondroblastoma lesions and detection of any local recurrence was assessed on clinical and radiological bases. The functional outcome was assessed by the Musculoskeletal Tumour Society scoring system.

Results

The mean follow-up period was 49 months. The average time for bone healing was 7.4 months. Our rate of local recurrence is 7.1 %. Two patients (14.3 %) developed physeal growth arrest. One patient had superficial skin sloughing (7.1 %). None of the cases had pathological fracture. The mean Musculoskeletal Tumour Society functional score was 92.7 %.

Conclusion

Chondroblastoma is an aggressive benign bone tumour with a high rate of recurrence. The use of high-speed burr combined with adjuvant intralesional cryotherapy and iliac crest autogenous bone grafting is a reliable method of treatment with a low rate of recurrence.
Literature
1.
go back to reference Campanacci M (1999) Bone and soft tissue tumors: clinical features, imaging, pathology, and treatment. Springer, New York and Piccin Nuova Libraria, Padova, Italy Campanacci M (1999) Bone and soft tissue tumors: clinical features, imaging, pathology, and treatment. Springer, New York and Piccin Nuova Libraria, Padova, Italy
2.
3.
go back to reference Schajowicz F, Gallardo H (1970) Epiphysial chondroblastoma of bone: a climco-pathological study of sixty-nine cases. J Bone Joint Surg Br 52-B(2):205–226 Schajowicz F, Gallardo H (1970) Epiphysial chondroblastoma of bone: a climco-pathological study of sixty-nine cases. J Bone Joint Surg Br 52-B(2):205–226
4.
go back to reference Springfield DS, Capanna R, Gherlinzoni F, Picci P, Campanacci M (1985) Chondroblastoma. A review of seventy cases. J Bone Joint Surg Am 67(5):748–755PubMed Springfield DS, Capanna R, Gherlinzoni F, Picci P, Campanacci M (1985) Chondroblastoma. A review of seventy cases. J Bone Joint Surg Am 67(5):748–755PubMed
5.
go back to reference Hsu CC, Wang JW, Chen CE, Lin JW (2003) Results of curettage and high-speed burring for chondroblastoma of the bone. Chang Gung Med J 26(10):761–767PubMed Hsu CC, Wang JW, Chen CE, Lin JW (2003) Results of curettage and high-speed burring for chondroblastoma of the bone. Chang Gung Med J 26(10):761–767PubMed
8.
go back to reference Garin IE, Wang EH (2008) Chondroblastoma. J Orthop Surg (Hong Kong) 16(1):84–87 Garin IE, Wang EH (2008) Chondroblastoma. J Orthop Surg (Hong Kong) 16(1):84–87
9.
go back to reference Jaffe HL, Lichtenstein L (1942) Benign chondroblastoma of bone: a reinterpretation of the so-called calcifying or chondromatous giant cell tumor. Am J Pathol 18(6):969–991PubMedCentralPubMed Jaffe HL, Lichtenstein L (1942) Benign chondroblastoma of bone: a reinterpretation of the so-called calcifying or chondromatous giant cell tumor. Am J Pathol 18(6):969–991PubMedCentralPubMed
10.
go back to reference Erler K, Yildiz C, Demiralp B, Ozdemir MT, Basbozkurt M (2003) Chondroblastoma of the distal femur. A case report. Acta Orthop Belg 69(5):467–472PubMed Erler K, Yildiz C, Demiralp B, Ozdemir MT, Basbozkurt M (2003) Chondroblastoma of the distal femur. A case report. Acta Orthop Belg 69(5):467–472PubMed
11.
go back to reference Aboulafia AJ, Kennon RE, Jelinek JS (1999) Begnign bone tumors of childhood. J Am Acad Orthop Surg 7(6):377–388PubMed Aboulafia AJ, Kennon RE, Jelinek JS (1999) Begnign bone tumors of childhood. J Am Acad Orthop Surg 7(6):377–388PubMed
12.
go back to reference Fletcher CDM, Unni KK, Mertens F (2002) World Health Organization Classification of Tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon Fletcher CDM, Unni KK, Mertens F (2002) World Health Organization Classification of Tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon
14.
go back to reference Ramappa AJ, Lee FY, Tang P, Carlson JR, Gebhardt MC, Mankin HJ (2000) Chondroblastoma of bone. J Bone Joint Surg Am 82-A(8):1140–1145PubMed Ramappa AJ, Lee FY, Tang P, Carlson JR, Gebhardt MC, Mankin HJ (2000) Chondroblastoma of bone. J Bone Joint Surg Am 82-A(8):1140–1145PubMed
16.
go back to reference Enneking WF (1986) A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res 204:9–24PubMed Enneking WF (1986) A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res 204:9–24PubMed
17.
go back to reference Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ (1993) A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res 286:241–246PubMed Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ (1993) A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res 286:241–246PubMed
18.
go back to reference Brien EW, Mirra JM, Kerr R (1997) Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. I. The intramedullary cartilage tumors. Skelet Radiol 26(6):325–353CrossRef Brien EW, Mirra JM, Kerr R (1997) Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. I. The intramedullary cartilage tumors. Skelet Radiol 26(6):325–353CrossRef
19.
go back to reference Huvos AG, Marcove RC, Erlandson RA, Mike V (1972) Chondroblastoma of bone. A clinicopathologic and electron microscopic study. Cancer 29(3):760–771PubMedCrossRef Huvos AG, Marcove RC, Erlandson RA, Mike V (1972) Chondroblastoma of bone. A clinicopathologic and electron microscopic study. Cancer 29(3):760–771PubMedCrossRef
20.
go back to reference Schreuder HW, Pruszczynski M, Veth RP, Lemmens JA (1998) Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery. Eur J Surg Oncol 24(2):120–126PubMedCrossRef Schreuder HW, Pruszczynski M, Veth RP, Lemmens JA (1998) Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery. Eur J Surg Oncol 24(2):120–126PubMedCrossRef
21.
go back to reference Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM (2001) Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. Radiology 221(2):463–468PubMedCrossRef Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM (2001) Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. Radiology 221(2):463–468PubMedCrossRef
22.
go back to reference Lim CT, Tan LB, Nathan SS (2012) Prospective evaluation of argon gas probe delivery for cryotherapy of bone tumours. Ann Acad Med Singapore 41(8):347–353PubMed Lim CT, Tan LB, Nathan SS (2012) Prospective evaluation of argon gas probe delivery for cryotherapy of bone tumours. Ann Acad Med Singapore 41(8):347–353PubMed
24.
go back to reference Bickels J, Kollender Y, Merimsky O, Isaakov J, Petyan-Brand R, Meller I (2004) Closed argon-based cryoablation of bone tumours. J Bone Joint Surg Br 86(5):714–718PubMedCrossRef Bickels J, Kollender Y, Merimsky O, Isaakov J, Petyan-Brand R, Meller I (2004) Closed argon-based cryoablation of bone tumours. J Bone Joint Surg Br 86(5):714–718PubMedCrossRef
25.
go back to reference Kyriakos M, Land VJ, Penning HL, Parker SG (1985) Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma. Cancer 55(8):1770–1789PubMedCrossRef Kyriakos M, Land VJ, Penning HL, Parker SG (1985) Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma. Cancer 55(8):1770–1789PubMedCrossRef
26.
go back to reference Rodgers WB, Mankin HJ (1996) Metastatic malignant chondroblastoma. Am J Orthop (Belle Mead NJ) 25(12):846–849 Rodgers WB, Mankin HJ (1996) Metastatic malignant chondroblastoma. Am J Orthop (Belle Mead NJ) 25(12):846–849
29.
go back to reference Tomic S, Lešić A, Bumbaširević M, Sopta J, Rakočević Z, Atkinson HD (2010) An aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov technique: A case report. J Orthop Surg Res 5:47 Tomic S, Lešić A, Bumbaširević M, Sopta J, Rakočević Z, Atkinson HD (2010) An aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov technique: A case report. J Orthop Surg Res 5:47
Metadata
Title
Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery
Authors
Mohamed Ahmed Mashhour
Mohamed Abdel Rahman
Publication date
01-05-2014
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 5/2014
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-013-2178-9

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