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Published in: Abdominal Radiology 11/2020

01-11-2020 | Prostate Cancer | Review

Magnetic resonance imaging of the prostate after focal therapy with high-intensity focused ultrasound

Authors: Soleen Ghafoor, Anton S. Becker, Daniel Stocker, Borna K. Barth, Daniel Eberli, Olivio F. Donati, Hebert Alberto Vargas

Published in: Abdominal Radiology | Issue 11/2020

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Abstract

For clinically significant, locally confined prostate cancer, whole-gland radical prostatectomy and radiotherapy are established effective treatment strategies that, however, come at a cost of significant morbidity related to urinary and sexual side effects. The concept of risk stratification paired with a better understanding of prognostic factors has led to the development of alternative management options including active surveillance and focal therapy for appropriately selected patients with localized disease. High-intensity focused ultrasound (HIFU) is one such minimally invasive, image-guided treatment option for prostate cancer. Due to the relative novelty of HIFU and the increased use of magnetic resonance imaging in prostate cancer, many radiologists are not yet familiar with imaging findings related to HIFU, their temporal evolution as well as imaging appearance of recurrent disease after this type of focal therapy. HIFU induces sharply demarcated, localized coagulative necrosis of a tumor through thermal energy delivered via an endorectal or transurethral ultrasound transducer. In this pictorial review, we aim at providing relevant background information that will guide the reader through the general principles of HIFU in the prostate, as well as demonstrate the imaging appearance of expected post-HIFU changes versus recurrent tumor.
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Metadata
Title
Magnetic resonance imaging of the prostate after focal therapy with high-intensity focused ultrasound
Authors
Soleen Ghafoor
Anton S. Becker
Daniel Stocker
Borna K. Barth
Daniel Eberli
Olivio F. Donati
Hebert Alberto Vargas
Publication date
01-11-2020
Publisher
Springer US
Published in
Abdominal Radiology / Issue 11/2020
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-020-02577-5

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