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Published in: Abdominal Radiology 7/2015

01-10-2015 | Review Article

Quantitative assessment of solid renal masses by contrast-enhanced ultrasound with time–intensity curves: how we do it

Authors: Kevin G. King, Mittul Gulati, Harshawn Malhi, Darryl Hwang, Inderbir S. Gill, Phillip M. Cheng, Edward G. Grant, Vinay A. Duddalwar

Published in: Abdominal Radiology | Issue 7/2015

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Abstract

Purpose

To discuss the evaluation of the enhancement curve over time of the major renal cell carcinoma (RCC) subtypes, oncocytoma, and lipid-poor angiomyolipoma, to aid in the preoperative differentiation of these entities. Differentiation of these lesions is important, given the different prognoses of the subtypes, as well as the desire to avoid resecting benign lesions.

Methods

We discuss findings from CT, MR, and US, but with a special emphasis on contrast-enhanced ultrasound (CEUS). CEUS technique is described, as well as time–intensity curve analysis.

Results

Examples of each of the major RCC subtypes (clear cell, papillary, and chromophobe) are shown, as well as examples of oncocytoma and lipid-poor angiomyolipoma. For each lesion, the time–intensity curve of enhancement on CEUS is reviewed, and correlated with the enhancement curve over time reported for multiphase CT and MR.

Conclusions

Preoperative differentiation of the most common solid renal masses is important, and the time–intensity curves of these lesions show some distinguishing features that can aid in this differentiation. The use of CEUS is increasing, and as a modality it is especially well suited to the evaluation of the time–intensity curve.
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Metadata
Title
Quantitative assessment of solid renal masses by contrast-enhanced ultrasound with time–intensity curves: how we do it
Authors
Kevin G. King
Mittul Gulati
Harshawn Malhi
Darryl Hwang
Inderbir S. Gill
Phillip M. Cheng
Edward G. Grant
Vinay A. Duddalwar
Publication date
01-10-2015
Publisher
Springer US
Published in
Abdominal Radiology / Issue 7/2015
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-015-0468-y

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