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Published in: Abdominal Radiology 4/2015

01-04-2015

Ultrasound elastography: liver

Authors: Manish Dhyani, Arash Anvari, Anthony E. Samir

Published in: Abdominal Radiology | Issue 4/2015

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Abstract

Ultrasound elastography, also termed sonoelastography, is being used increasingly in clinical practice to aid the diagnosis and management of diffuse liver disease. Elastography has been shown to be capable of differentiating advanced and early-stage liver fibrosis, and consequently a major application in clinical liver care includes progression to cirrhosis risk stratification through (1) assessment of liver fibrosis stage in HCV and HBV patients, (2) distinguishing non-alcoholic steatohepatitis from simple steatosis in non-alcoholic fatty liver disease patients, and (3) prognostic evaluation of liver disease is autoimmune liver disease. In addition, elastographic characterization of focal liver lesions and evaluation of clinically significant portal hypertension have the potential to be clinically useful and are areas of active clinical research.
Literature
1.
go back to reference Younossi ZM, Stepanova M, Afendy M, et al. (2011) Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin Gastroenterol Hepatol 9:524–530 (e1– quiz e60). doi:10.1016/j.cgh.2011.03.020 PubMed Younossi ZM, Stepanova M, Afendy M, et al. (2011) Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin Gastroenterol Hepatol 9:524–530 (e1– quiz e60). doi:10.​1016/​j.​cgh.​2011.​03.​020 PubMed
2.
5.
go back to reference Schölmerich J, Holstege A (1990) Aetiology and pathophysiology of chronic liver disorders. Drugs 40(Suppl 3):3–22PubMed Schölmerich J, Holstege A (1990) Aetiology and pathophysiology of chronic liver disorders. Drugs 40(Suppl 3):3–22PubMed
6.
go back to reference Pellicoro A, Ramachandran P, Iredale JP, Fallowfield JA (2014) Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol 14:181–194. doi:10.1038/nri3623 PubMed Pellicoro A, Ramachandran P, Iredale JP, Fallowfield JA (2014) Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol 14:181–194. doi:10.​1038/​nri3623 PubMed
7.
8.
go back to reference The French METAVIR Cooperative Study Group (1994) Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology 20:15–20 The French METAVIR Cooperative Study Group (1994) Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology 20:15–20
9.
go back to reference Ishak K, Baptista A, Bianchi L, et al. (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22:696–699PubMed Ishak K, Baptista A, Bianchi L, et al. (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22:696–699PubMed
10.
go back to reference Mannan R, Misra V, Misra SP, Singh PA, Dwivedi M (2014) A comparative evaluation of scoring systems for assessing necro-inflammatory activity and fibrosis in liver biopsies of patients with chronic viral hepatitis. 10.7860/JCDR/2014/8704.4718 8:FC08–FC12 Mannan R, Misra V, Misra SP, Singh PA, Dwivedi M (2014) A comparative evaluation of scoring systems for assessing necro-inflammatory activity and fibrosis in liver biopsies of patients with chronic viral hepatitis. 10.7860/JCDR/2014/8704.4718 8:FC08–FC12
11.
go back to reference Actis GC, Olivero A, Lagget M, et al. (2007) The practice of percutaneous liver biopsy in a gastrohepatology day hospital: a retrospective study on 835 biopsies. Dig Dis Sci 52:2576–2579. doi:10.1007/s10620-006-9724-x PubMed Actis GC, Olivero A, Lagget M, et al. (2007) The practice of percutaneous liver biopsy in a gastrohepatology day hospital: a retrospective study on 835 biopsies. Dig Dis Sci 52:2576–2579. doi:10.​1007/​s10620-006-9724-x PubMed
12.
go back to reference Cadranel JF, Rufat P, Degos F (2000) Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF). Hepatology 32:477–481. doi:10.1053/jhep.2000.16602 PubMed Cadranel JF, Rufat P, Degos F (2000) Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF). Hepatology 32:477–481. doi:10.​1053/​jhep.​2000.​16602 PubMed
14.
go back to reference Sparchez Z (2005) Complications after percutaneous liver biopsy in diffuse hepatopathies. Rom J Gastroenterol 14:379–384PubMed Sparchez Z (2005) Complications after percutaneous liver biopsy in diffuse hepatopathies. Rom J Gastroenterol 14:379–384PubMed
16.
go back to reference Rousselet M-C, Michalak S, Dupré F, et al. (2005) Sources of variability in histological scoring of chronic viral hepatitis. Hepatology 41:257–264. doi:10.1002/hep.20535 PubMed Rousselet M-C, Michalak S, Dupré F, et al. (2005) Sources of variability in histological scoring of chronic viral hepatitis. Hepatology 41:257–264. doi:10.​1002/​hep.​20535 PubMed
19.
20.
go back to reference Wai C-T, Greenson JK, Fontana RJ, et al. (2003) A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 38:518–526. doi:10.1053/jhep.2003.50346 PubMed Wai C-T, Greenson JK, Fontana RJ, et al. (2003) A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 38:518–526. doi:10.​1053/​jhep.​2003.​50346 PubMed
21.
go back to reference Rosenberg WMC, Voelker M, Thiel R, et al. (2004) Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology 127:1704–1713PubMed Rosenberg WMC, Voelker M, Thiel R, et al. (2004) Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology 127:1704–1713PubMed
23.
25.
26.
go back to reference Sterling RK, Lissen E, Clumeck N et al. (2006) Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 43:1317–1325. doi: 10.1002/hep.21178 Sterling RK, Lissen E, Clumeck N et al. (2006) Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 43:1317–1325. doi: 10.​1002/​hep.​21178
27.
go back to reference Wang Q-B, Zhu H, Liu H-L, Zhang B (2012) Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis. Hepatology 56:239–247. doi:10.1002/hep.25610 PubMed Wang Q-B, Zhu H, Liu H-L, Zhang B (2012) Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis. Hepatology 56:239–247. doi:10.​1002/​hep.​25610 PubMed
29.
go back to reference Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST (2013) Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 57:1333–1342. doi:10.1002/hep.26141 PubMed Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST (2013) Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 57:1333–1342. doi:10.​1002/​hep.​26141 PubMed
31.
go back to reference Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH (2000) Pathogenesis, natural history, treatment, and prevention of hepatitis C. Ann Intern Med 132:296–305 Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH (2000) Pathogenesis, natural history, treatment, and prevention of hepatitis C. Ann Intern Med 132:296–305
33.
go back to reference Thein H-H, Yi Q, Dore GJ, Krahn MD (2008) Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression. Hepatology 48:418–431. doi:10.1002/hep.22375 PubMed Thein H-H, Yi Q, Dore GJ, Krahn MD (2008) Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression. Hepatology 48:418–431. doi:10.​1002/​hep.​22375 PubMed
34.
go back to reference Poynard T, Bedossa P, Opolon P, The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups (1997) Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 349:825–832PubMed Poynard T, Bedossa P, Opolon P, The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups (1997) Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 349:825–832PubMed
37.
38.
go back to reference Castera L, Vergniol J, Foucher J, et al. (2005) Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 128:343–350PubMed Castera L, Vergniol J, Foucher J, et al. (2005) Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 128:343–350PubMed
39.
go back to reference Sporea I, Sirli R, Deleanu A, Popescu A, Cornianu M (2008) Liver stiffness measurement by transient elastography in clinical practice. J Gastrointestin Liver Dis 17:395–399PubMed Sporea I, Sirli R, Deleanu A, Popescu A, Cornianu M (2008) Liver stiffness measurement by transient elastography in clinical practice. J Gastrointestin Liver Dis 17:395–399PubMed
40.
go back to reference Sporea I, Sirli R, Deleanu A, et al. (2008) Comparison of the liver stiffness measurement by transient elastography with the liver biopsy. World J Gastroenterol 14:6513–6517PubMedCentralPubMed Sporea I, Sirli R, Deleanu A, et al. (2008) Comparison of the liver stiffness measurement by transient elastography with the liver biopsy. World J Gastroenterol 14:6513–6517PubMedCentralPubMed
42.
go back to reference Masuzaki R, Tateishi R, Yoshida H, et al. (2008) Comparison of liver biopsy and transient elastography based on clinical relevance. Canadian journal of gastroenterology =. J Can de Gastroenterologie 22:753–757 Masuzaki R, Tateishi R, Yoshida H, et al. (2008) Comparison of liver biopsy and transient elastography based on clinical relevance. Canadian journal of gastroenterology =. J Can de Gastroenterologie 22:753–757
43.
go back to reference Lupsor M, Badea R, Stefanescu H, et al. (2008) Analysis of histopathological changes that influence liver stiffness in chronic hepatitis C. Results from a cohort of 324 patients. J Gastrointest Liver Dis 17:155–163 Lupsor M, Badea R, Stefanescu H, et al. (2008) Analysis of histopathological changes that influence liver stiffness in chronic hepatitis C. Results from a cohort of 324 patients. J Gastrointest Liver Dis 17:155–163
45.
go back to reference Sporea I, Sirli R, Bota S, et al. (2012) Comparative study concerning the value of acoustic radiation force impulse elastography (ARFI) in comparison with transient elastography (TE) for the assessment of liver fibrosis in patients with chronic hepatitis B and C. Ultrasound Med Biol 38:1310–1316. doi:10.1016/j.ultrasmedbio.2012.03.011 PubMed Sporea I, Sirli R, Bota S, et al. (2012) Comparative study concerning the value of acoustic radiation force impulse elastography (ARFI) in comparison with transient elastography (TE) for the assessment of liver fibrosis in patients with chronic hepatitis B and C. Ultrasound Med Biol 38:1310–1316. doi:10.​1016/​j.​ultrasmedbio.​2012.​03.​011 PubMed
46.
go back to reference Rizzo L, Calvaruso V, Cacopardo B, et al. (2011) Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatitis C. Am J Gastroenterol 106:2112–2120. doi:10.1038/ajg.2011.341 PubMed Rizzo L, Calvaruso V, Cacopardo B, et al. (2011) Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatitis C. Am J Gastroenterol 106:2112–2120. doi:10.​1038/​ajg.​2011.​341 PubMed
47.
go back to reference Ferraioli G, Tinelli C, Dal Bello B et al. (2012) Accuracy of real-time shear wave elastography for assessing liver fibrosis in chronic hepatitis C: a pilot study. Hepatology 56:2125–2133. doi: 10.1002/hep.25936 Ferraioli G, Tinelli C, Dal Bello B et al. (2012) Accuracy of real-time shear wave elastography for assessing liver fibrosis in chronic hepatitis C: a pilot study. Hepatology 56:2125–2133. doi: 10.​1002/​hep.​25936
48.
go back to reference Samir AE, Dhyani M, Vij A, et al. (2014) Shear-Wave Elastography for the Estimation of Liver Fibrosis in Chronic Liver Disease: determining Accuracy and Ideal Site for Measurement. Radiology . doi:10.1148/radiol.14140839 Samir AE, Dhyani M, Vij A, et al. (2014) Shear-Wave Elastography for the Estimation of Liver Fibrosis in Chronic Liver Disease: determining Accuracy and Ideal Site for Measurement. Radiology . doi:10.​1148/​radiol.​14140839
49.
go back to reference Sporea I, Bota S, Peck-Radosavljevic M, et al. (2012) Acoustic Radiation Force Impulse elastography for fibrosis evaluation in patients with chronic hepatitis C: an international multicenter study. Eur J Radiol 81:4112–4118. doi:10.1016/j.ejrad.2012.08.018 PubMed Sporea I, Bota S, Peck-Radosavljevic M, et al. (2012) Acoustic Radiation Force Impulse elastography for fibrosis evaluation in patients with chronic hepatitis C: an international multicenter study. Eur J Radiol 81:4112–4118. doi:10.​1016/​j.​ejrad.​2012.​08.​018 PubMed
50.
go back to reference Lupsor M, Badea R, Stefanescu H, et al. (2009) Performance of a new elastographic method (ARFI technology) compared to unidimensional transient elastography in the noninvasive assessment of chronic hepatitis C Preliminary results. J Gastrointestin Liver Dis 18:303–310PubMed Lupsor M, Badea R, Stefanescu H, et al. (2009) Performance of a new elastographic method (ARFI technology) compared to unidimensional transient elastography in the noninvasive assessment of chronic hepatitis C Preliminary results. J Gastrointestin Liver Dis 18:303–310PubMed
55.
go back to reference Oliveri F, Coco B, Ciccorossi P, et al. (2008) Liver stiffness in the hepatitis B virus carrier: a non-invasive marker of liver disease influenced by the pattern of transaminases. World J Gastroenterol 14:6154–6162PubMedCentralPubMed Oliveri F, Coco B, Ciccorossi P, et al. (2008) Liver stiffness in the hepatitis B virus carrier: a non-invasive marker of liver disease influenced by the pattern of transaminases. World J Gastroenterol 14:6154–6162PubMedCentralPubMed
60.
go back to reference Chan HL-Y, Wong GL-H, Choi PC-L, et al. (2009) Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B. J Viral Hepat 16:36–44. doi:10.1111/j.1365-2893.2008.01037.x PubMed Chan HL-Y, Wong GL-H, Choi PC-L, et al. (2009) Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B. J Viral Hepat 16:36–44. doi:10.​1111/​j.​1365-2893.​2008.​01037.​x PubMed
62.
go back to reference Degos F, Perez P, Roche B, et al. (2010) Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study). J Hepatol 53:1013–1021. doi:10.1016/j.jhep.2010.05.035 PubMed Degos F, Perez P, Roche B, et al. (2010) Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study). J Hepatol 53:1013–1021. doi:10.​1016/​j.​jhep.​2010.​05.​035 PubMed
64.
go back to reference Zhang D, Chen M, Wang R, et al. (2015) Comparison of Acoustic Radiation Force Impulse Imaging and Transient Elastography for Non-invasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B. Ultrasound Med Biol 41:7–14. doi:10.1016/j.ultrasmedbio.2014.07.018 PubMed Zhang D, Chen M, Wang R, et al. (2015) Comparison of Acoustic Radiation Force Impulse Imaging and Transient Elastography for Non-invasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B. Ultrasound Med Biol 41:7–14. doi:10.​1016/​j.​ultrasmedbio.​2014.​07.​018 PubMed
65.
go back to reference Chalasani N, Younossi Z, Lavine JE et al. (2012) The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 142:1592–1609. doi: 10.1053/j.gastro.2012.04.001 Chalasani N, Younossi Z, Lavine JE et al. (2012) The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 142:1592–1609. doi: 10.​1053/​j.​gastro.​2012.​04.​001
66.
68.
go back to reference Motosugi U, Ichikawa T, Niitsuma Y, Araki T (2011) Acoustic radiation force impulse elastography of the liver: can fat deposition in the liver affect the measurement of liver stiffness? Jpn J Radiol 29:639–643. doi:10.1007/s11604-011-0607-5 PubMed Motosugi U, Ichikawa T, Niitsuma Y, Araki T (2011) Acoustic radiation force impulse elastography of the liver: can fat deposition in the liver affect the measurement of liver stiffness? Jpn J Radiol 29:639–643. doi:10.​1007/​s11604-011-0607-5 PubMed
69.
go back to reference Ebinuma H, Saito H, Komuta M, et al. (2011) Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan((R)). J Gastroenterol 46:1238–1248. doi:10.1007/s00535-011-0437-3 PubMed Ebinuma H, Saito H, Komuta M, et al. (2011) Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan((R)). J Gastroenterol 46:1238–1248. doi:10.​1007/​s00535-011-0437-3 PubMed
70.
go back to reference Bota S, Sporea I, Sirli R, Popescu A, Jurchis A (2013) Factors which influence the accuracy of acoustic radiation force impulse (ARFI) elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis C. Ultrasound Med Biol. doi: 10.1016/j.ultrasmedbio.2012.09.017. (null:407–412) Bota S, Sporea I, Sirli R, Popescu A, Jurchis A (2013) Factors which influence the accuracy of acoustic radiation force impulse (ARFI) elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis C. Ultrasound Med Biol. doi: 10.​1016/​j.​ultrasmedbio.​2012.​09.​017. (null:407–412)
71.
go back to reference Poynard T, Munteanu M, Luckina E, et al. (2013) Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard. J Hepatol 58:928–935. doi:10.1016/j.jhep.2012.12.021 PubMed Poynard T, Munteanu M, Luckina E, et al. (2013) Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard. J Hepatol 58:928–935. doi:10.​1016/​j.​jhep.​2012.​12.​021 PubMed
72.
go back to reference Chen S-H, Li Y-F, Lai H-C, et al. (2012) Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C. BMC Gastroenterology 12:105. doi:10.1186/1471-230X-12-105 PubMedCentralPubMed Chen S-H, Li Y-F, Lai H-C, et al. (2012) Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C. BMC Gastroenterology 12:105. doi:10.​1186/​1471-230X-12-105 PubMedCentralPubMed
73.
go back to reference Yoon KT, Lim SM, Park JY, et al. (2012) Liver stiffness measurement using acoustic radiation force impulse (ARFI) elastography and effect of necroinflammation. Dig Dis Sci 57:1682–1691. doi:10.1007/s10620-012-2044-4 PubMed Yoon KT, Lim SM, Park JY, et al. (2012) Liver stiffness measurement using acoustic radiation force impulse (ARFI) elastography and effect of necroinflammation. Dig Dis Sci 57:1682–1691. doi:10.​1007/​s10620-012-2044-4 PubMed
74.
go back to reference Guzmán-Aroca F, Frutos-Bernal MD, Bas A et al. (2012) Detection of non-alcoholic steatohepatitis in patients with morbid obesity before bariatric surgery: preliminary evaluation with acoustic radiation force impulse imaging. Eur Radiol 22:2525–2532. doi: 10.1007/s00330-012-2505-3 Guzmán-Aroca F, Frutos-Bernal MD, Bas A et al. (2012) Detection of non-alcoholic steatohepatitis in patients with morbid obesity before bariatric surgery: preliminary evaluation with acoustic radiation force impulse imaging. Eur Radiol 22:2525–2532. doi: 10.​1007/​s00330-012-2505-3
75.
go back to reference Bota S, Sporea I, Peck-Radosavljevic M, et al. (2013) The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: a retrospective multicentre study. Dig Liver Dis 45:762–768. doi:10.1016/j.dld.2013.02.008 PubMed Bota S, Sporea I, Peck-Radosavljevic M, et al. (2013) The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: a retrospective multicentre study. Dig Liver Dis 45:762–768. doi:10.​1016/​j.​dld.​2013.​02.​008 PubMed
76.
go back to reference Fierbinteanu-Braticevici C, Sporea I, Panaitescu E, Tribus L (2013) Value of acoustic radiation force impulse imaging elastography for non-invasive evaluation of patients with nonalcoholic fatty liver disease. Ultrasound Med Biol 39:1942–1950. doi:10.1016/j.ultrasmedbio.2013.04.019 PubMed Fierbinteanu-Braticevici C, Sporea I, Panaitescu E, Tribus L (2013) Value of acoustic radiation force impulse imaging elastography for non-invasive evaluation of patients with nonalcoholic fatty liver disease. Ultrasound Med Biol 39:1942–1950. doi:10.​1016/​j.​ultrasmedbio.​2013.​04.​019 PubMed
77.
go back to reference Takaki S, Kawakami Y, Miyaki D, et al. (2014) Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients. Hepatol Res 44:280–287. doi:10.1111/hepr.12129 PubMed Takaki S, Kawakami Y, Miyaki D, et al. (2014) Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients. Hepatol Res 44:280–287. doi:10.​1111/​hepr.​12129 PubMed
78.
go back to reference Yoneda M, Mawatari H, Fujita K, et al. (2008) Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with nonalcoholic fatty liver disease (NAFLD). Dig Liver Dis 40:371–378. doi:10.1016/j.dld.2007.10.019 PubMed Yoneda M, Mawatari H, Fujita K, et al. (2008) Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with nonalcoholic fatty liver disease (NAFLD). Dig Liver Dis 40:371–378. doi:10.​1016/​j.​dld.​2007.​10.​019 PubMed
79.
go back to reference Wong VW-S, Vergniol J, Wong GL-H, et al. (2010) Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 51:454–462. doi:10.1002/hep.23312 PubMed Wong VW-S, Vergniol J, Wong GL-H, et al. (2010) Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 51:454–462. doi:10.​1002/​hep.​23312 PubMed
80.
go back to reference Lupsor M, Badea R, Stefanescu H, et al. (2010) Performance of unidimensional transient elastography in staging non-alcoholic steatohepatitis. J Gastrointestin Liver Dis 19:53–60PubMed Lupsor M, Badea R, Stefanescu H, et al. (2010) Performance of unidimensional transient elastography in staging non-alcoholic steatohepatitis. J Gastrointestin Liver Dis 19:53–60PubMed
82.
go back to reference Wong VW-S, Vergniol J, Wong GL-H, et al. (2012) Liver stiffness measurement using XL probe in patients with nonalcoholic fatty liver disease. Am J Gastroenterol 107:1862–1871. doi:10.1038/ajg.2012.331 PubMed Wong VW-S, Vergniol J, Wong GL-H, et al. (2012) Liver stiffness measurement using XL probe in patients with nonalcoholic fatty liver disease. Am J Gastroenterol 107:1862–1871. doi:10.​1038/​ajg.​2012.​331 PubMed
83.
go back to reference Myers RP, Pomier-Layrargues G, Kirsch R, et al. (2012) Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients. Hepatology 55:199–208. doi:10.1002/hep.24624 PubMed Myers RP, Pomier-Layrargues G, Kirsch R, et al. (2012) Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients. Hepatology 55:199–208. doi:10.​1002/​hep.​24624 PubMed
85.
go back to reference Yoshioka K, Hashimoto S, Kawabe N (2014) Measurement of liver stiffness as a non-invasive method for diagnosis of non-alcoholic fatty liver disease. Hepatol Res . doi:10.1111/hepr.12388 Yoshioka K, Hashimoto S, Kawabe N (2014) Measurement of liver stiffness as a non-invasive method for diagnosis of non-alcoholic fatty liver disease. Hepatol Res . doi:10.​1111/​hepr.​12388
86.
go back to reference Hoyert DL, Xu J (2012) Deaths: preliminary data for 2011. Natl Vital Stat Rep 61:1–51PubMed Hoyert DL, Xu J (2012) Deaths: preliminary data for 2011. Natl Vital Stat Rep 61:1–51PubMed
89.
go back to reference Nguyen-Khac E, Chatelain D, Tramier B, et al. (2008) Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Aliment Pharmacol Ther 28:1188–1198. doi:10.1111/j.1365-2036.2008.03831.x PubMed Nguyen-Khac E, Chatelain D, Tramier B, et al. (2008) Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Aliment Pharmacol Ther 28:1188–1198. doi:10.​1111/​j.​1365-2036.​2008.​03831.​x PubMed
90.
go back to reference Zhang D, Li P, Chen M, et al. (2014) Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease using acoustic radiation force impulse elastography. Abdom Imaging . doi:10.1007/s00261-014-0154-5 Zhang D, Li P, Chen M, et al. (2014) Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease using acoustic radiation force impulse elastography. Abdom Imaging . doi:10.​1007/​s00261-014-0154-5
93.
go back to reference Corpechot C, El Naggar A, Poujol-Robert A, et al. (2006) Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC. Hepatology 43:1118–1124. doi:10.1002/hep.21151 PubMed Corpechot C, El Naggar A, Poujol-Robert A, et al. (2006) Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC. Hepatology 43:1118–1124. doi:10.​1002/​hep.​21151 PubMed
94.
go back to reference Zhang D-K, Chen M, Liu Y, et al. (2014) Acoustic radiation force impulse elastography for non-invasive assessment of disease stage in patients with primary biliary cirrhosis: a preliminary study. Clin Radiol 69:836–840. doi:10.1016/j.crad.2014.03.019 PubMed Zhang D-K, Chen M, Liu Y, et al. (2014) Acoustic radiation force impulse elastography for non-invasive assessment of disease stage in patients with primary biliary cirrhosis: a preliminary study. Clin Radiol 69:836–840. doi:10.​1016/​j.​crad.​2014.​03.​019 PubMed
95.
go back to reference Whiting-O’Keefe QE, Fye KH, Sack KD (1991) Methotrexate and histologic hepatic abnormalities: a meta-analysis. Am J Med 90:711–716PubMed Whiting-O’Keefe QE, Fye KH, Sack KD (1991) Methotrexate and histologic hepatic abnormalities: a meta-analysis. Am J Med 90:711–716PubMed
96.
go back to reference Bambha K, Kim WR, Talwalkar J, et al. (2003) Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community. Gastroenterology 125:1364–1369PubMed Bambha K, Kim WR, Talwalkar J, et al. (2003) Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community. Gastroenterology 125:1364–1369PubMed
97.
go back to reference Corpechot C, Gaouar F, El Naggar A, et al. (2014) Baseline values and changes in liver stiffness measured by transient elastography are associated with severity of fibrosis and outcomes of patients with primary sclerosing cholangitis. Gastroenterology 146:970–979 ((quiz e15–e16)). doi:10.1053/j.gastro.2013.12.030 PubMed Corpechot C, Gaouar F, El Naggar A, et al. (2014) Baseline values and changes in liver stiffness measured by transient elastography are associated with severity of fibrosis and outcomes of patients with primary sclerosing cholangitis. Gastroenterology 146:970–979 ((quiz e15–e16)). doi:10.​1053/​j.​gastro.​2013.​12.​030 PubMed
99.
go back to reference Righi S, Fiorini E, De Molo C, et al. (2012) ARFI elastography in patients with chronic autoimmune liver diseases: a preliminary study. J Ultrasound 15:226–231PubMedCentralPubMed Righi S, Fiorini E, De Molo C, et al. (2012) ARFI elastography in patients with chronic autoimmune liver diseases: a preliminary study. J Ultrasound 15:226–231PubMedCentralPubMed
101.
104.
go back to reference Heide R, Strobel D, Bernatik T, Goertz RS (2010) Characterization of focal liver lesions (FLL) with acoustic radiation force impulse (ARFI) elastometry. Ultraschall Med 31:405–409. doi:10.1055/s-0029-1245565 PubMed Heide R, Strobel D, Bernatik T, Goertz RS (2010) Characterization of focal liver lesions (FLL) with acoustic radiation force impulse (ARFI) elastometry. Ultraschall Med 31:405–409. doi:10.​1055/​s-0029-1245565 PubMed
106.
go back to reference Ronot M, Di Renzo S, Gregoli B, et al. (2014) Characterization of fortuitously discovered focal liver lesions: additional information provided by shearwave elastography. Eur Radiol . doi:10.1007/s00330-014-3370-z Ronot M, Di Renzo S, Gregoli B, et al. (2014) Characterization of fortuitously discovered focal liver lesions: additional information provided by shearwave elastography. Eur Radiol . doi:10.​1007/​s00330-014-3370-z
107.
109.
111.
go back to reference Zhang P, Zhou P, Tian S-M, et al. (2013) Application of acoustic radiation force impulse imaging for the evaluation of focal liver lesion elasticity. Hepatobiliary Pancreat Dis Int 12:165–170PubMed Zhang P, Zhou P, Tian S-M, et al. (2013) Application of acoustic radiation force impulse imaging for the evaluation of focal liver lesion elasticity. Hepatobiliary Pancreat Dis Int 12:165–170PubMed
117.
go back to reference de Franchis R (2005) Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension. J. Hepatol 43:167–176 de Franchis R (2005) Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension. J. Hepatol 43:167–176
118.
go back to reference Garcia-Tsao G, Friedman S, Iredale J, Pinzani M (2010) Now there are many (stages) where before there was one: in search of a pathophysiological classification of cirrhosis. Hepatology 51:1445–1449. doi:10.1002/hep.23478 PubMedCentralPubMed Garcia-Tsao G, Friedman S, Iredale J, Pinzani M (2010) Now there are many (stages) where before there was one: in search of a pathophysiological classification of cirrhosis. Hepatology 51:1445–1449. doi:10.​1002/​hep.​23478 PubMedCentralPubMed
120.
go back to reference Shi K-Q, Fan Y-C, Pan Z-Z, et al. (2013) Transient elastography: a meta-analysis of diagnostic accuracy in evaluation of portal hypertension in chronic liver disease. Liver Int 33:62–71. doi:10.1111/liv.12003 PubMed Shi K-Q, Fan Y-C, Pan Z-Z, et al. (2013) Transient elastography: a meta-analysis of diagnostic accuracy in evaluation of portal hypertension in chronic liver disease. Liver Int 33:62–71. doi:10.​1111/​liv.​12003 PubMed
121.
go back to reference Elkrief L, Rautou P-E, Ronot M, et al. (2014) Prospective comparison of Spleen and liver stiffness by using shear-wave and transient elastography for detection of portal hypertension in cirrhosis. Radiology . doi:10.1148/radiol.14141210 PubMed Elkrief L, Rautou P-E, Ronot M, et al. (2014) Prospective comparison of Spleen and liver stiffness by using shear-wave and transient elastography for detection of portal hypertension in cirrhosis. Radiology . doi:10.​1148/​radiol.​14141210 PubMed
Metadata
Title
Ultrasound elastography: liver
Authors
Manish Dhyani
Arash Anvari
Anthony E. Samir
Publication date
01-04-2015
Publisher
Springer US
Published in
Abdominal Radiology / Issue 4/2015
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-015-0373-4

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