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Published in: Abdominal Radiology 5/2013

01-10-2013

MRI of perianal fistulas: bridging the radiological–surgical divide

Authors: Kenneth L. Gage, Swati Deshmukh, Katarzyna J. Macura, Ihab R. Kamel, Atif Zaheer

Published in: Abdominal Radiology | Issue 5/2013

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Abstract

Perianal fistula is a clinical entity with multiple surgical treatment options. Recently, magnetic resonance imaging (MRI) has emerged as an important imaging modality in the management of perianal fistulas. It provides accurate description of the fistula within the anal canal in relation to the sphincter complex and other pelvic floor structures as well as the associated complications such as abscess. By understanding the surgical viewpoint, the appearance of perianal fistulas, associated complications, and post-treatment findings of commonly used surgical interventions can more accurately be interpreted to aid clinicians. The objective of the article is to review MRI indications and findings, radiological versus surgical classification schemes, and surgical treatment options for perianal fistulas.
Literature
1.
go back to reference Zanotti C, Martinez-Puente C, Pascual I, et al. (2007) An assessment of the incidence of fistula-in-ano in four countries of the European Union. Int J Colorectal Dis 22(12):1459–1462PubMedCrossRef Zanotti C, Martinez-Puente C, Pascual I, et al. (2007) An assessment of the incidence of fistula-in-ano in four countries of the European Union. Int J Colorectal Dis 22(12):1459–1462PubMedCrossRef
2.
go back to reference Sainio P (1984) Fistula-in-ano in a defined population. Incidence and epidemiological aspects. Ann Chir Gynaecol 73(4):219–224PubMed Sainio P (1984) Fistula-in-ano in a defined population. Incidence and epidemiological aspects. Ann Chir Gynaecol 73(4):219–224PubMed
3.
go back to reference Morris J, Spencer JA, Ambrose NS (2000) MR imaging classification of perianal fistulas and its implications for patient management. Radiographics 20(3):623–635PubMed Morris J, Spencer JA, Ambrose NS (2000) MR imaging classification of perianal fistulas and its implications for patient management. Radiographics 20(3):623–635PubMed
4.
go back to reference Hamadani A, Haigh PI, Liu I-LA, Abbas MA (2009) Who is at risk for developing chronic anal fistula or recurrent anal sepsis after initial perianal abscess? Dis Colon Rectum 52(2):217–221PubMedCrossRef Hamadani A, Haigh PI, Liu I-LA, Abbas MA (2009) Who is at risk for developing chronic anal fistula or recurrent anal sepsis after initial perianal abscess? Dis Colon Rectum 52(2):217–221PubMedCrossRef
5.
go back to reference Schwartz DA, Loftus EV Jr, Tremaine WJ, et al. (2002) The natural history of fistulizing Crohn’s disease in Olmsted County, Minnesota. Gastroenterology 122(4):875–880PubMedCrossRef Schwartz DA, Loftus EV Jr, Tremaine WJ, et al. (2002) The natural history of fistulizing Crohn’s disease in Olmsted County, Minnesota. Gastroenterology 122(4):875–880PubMedCrossRef
6.
go back to reference Hellers G, Bergstrand O, Ewerth S, Holmström B (1980) Occurrence and outcome after primary treatment of anal fistulae in Crohn’s disease. Gut 21(6):525–527PubMedCrossRef Hellers G, Bergstrand O, Ewerth S, Holmström B (1980) Occurrence and outcome after primary treatment of anal fistulae in Crohn’s disease. Gut 21(6):525–527PubMedCrossRef
7.
go back to reference Karban A, Itay M, Davidovich O, et al. (2007) Risk factors for perianal Crohn’s disease: the role of genotype, phenotype, and ethnicity. Am J Gastroenterol 102(8):1702–1708PubMedCrossRef Karban A, Itay M, Davidovich O, et al. (2007) Risk factors for perianal Crohn’s disease: the role of genotype, phenotype, and ethnicity. Am J Gastroenterol 102(8):1702–1708PubMedCrossRef
8.
go back to reference Lohsiriwat V, Yodying H, Lohsiriwat D (2010) Incidence and factors influencing the development of fistula-in-ano after incision and drainage of perianal abscesses. J Med Assoc Thai 93(1):61–65PubMed Lohsiriwat V, Yodying H, Lohsiriwat D (2010) Incidence and factors influencing the development of fistula-in-ano after incision and drainage of perianal abscesses. J Med Assoc Thai 93(1):61–65PubMed
9.
go back to reference Devaraj B, Khabassi S, Cosman BC (2011) Recent smoking is a risk factor for anal abscess and fistula. Dis Colon Rectum 54(6):681–685PubMedCrossRef Devaraj B, Khabassi S, Cosman BC (2011) Recent smoking is a risk factor for anal abscess and fistula. Dis Colon Rectum 54(6):681–685PubMedCrossRef
11.
go back to reference Halligan S, Healy JC, Bartram CI (1998) Magnetic resonance imaging of fistula-in-ano: STIR or SPIR? Br J Radiol 71(842):141–145PubMed Halligan S, Healy JC, Bartram CI (1998) Magnetic resonance imaging of fistula-in-ano: STIR or SPIR? Br J Radiol 71(842):141–145PubMed
12.
go back to reference Sabir N, Sungurtekin U, Erdem E, Nessar M (2000) Magnetic resonance imaging with rectal Gd-DTPA: new tool for the diagnosis of perianal fistula. Int J Colorectal Dis 15(5–6):317–322PubMedCrossRef Sabir N, Sungurtekin U, Erdem E, Nessar M (2000) Magnetic resonance imaging with rectal Gd-DTPA: new tool for the diagnosis of perianal fistula. Int J Colorectal Dis 15(5–6):317–322PubMedCrossRef
13.
go back to reference Hori M, Oto A, Orrin S, Suzuki K, Baron RL (2009) Diffusion-weighted MRI: a new tool for the diagnosis of fistula in ano. J Magn Reson Imaging 30(5):1021–1026PubMedCrossRef Hori M, Oto A, Orrin S, Suzuki K, Baron RL (2009) Diffusion-weighted MRI: a new tool for the diagnosis of fistula in ano. J Magn Reson Imaging 30(5):1021–1026PubMedCrossRef
14.
go back to reference Yildirim N, Gökalp G, Öztürk E, et al. (2012) Ideal combination of MRI sequences for perianal fistula classification and the evaluation of additional findings for readers with varying levels of experience. Diagn Interv Radiol 18(1):11–19PubMed Yildirim N, Gökalp G, Öztürk E, et al. (2012) Ideal combination of MRI sequences for perianal fistula classification and the evaluation of additional findings for readers with varying levels of experience. Diagn Interv Radiol 18(1):11–19PubMed
15.
go back to reference Erturk SM, Alberich-Bayarri A, Herrmann KA, et al. (2009) Use of 3.0-T MR imaging for evaluation of the abdomen. Radiographics 29(6):1547–1563PubMedCrossRef Erturk SM, Alberich-Bayarri A, Herrmann KA, et al. (2009) Use of 3.0-T MR imaging for evaluation of the abdomen. Radiographics 29(6):1547–1563PubMedCrossRef
16.
go back to reference Libicher M, Scharf J, Wunsch A, et al. (1998) MRI of pouch-related fistulas in ulcerative colitis after restorative proctocolectomy. J Comput Assist Tomogr 22(4):664–668PubMedCrossRef Libicher M, Scharf J, Wunsch A, et al. (1998) MRI of pouch-related fistulas in ulcerative colitis after restorative proctocolectomy. J Comput Assist Tomogr 22(4):664–668PubMedCrossRef
17.
go back to reference Schaefer O, Lohrmann C, Langer M (2004) Assessment of anal fistulas with high-resolution subtraction MR-fistulography: comparison with surgical findings. J Magn Reson Imaging 19(1):91–98PubMedCrossRef Schaefer O, Lohrmann C, Langer M (2004) Assessment of anal fistulas with high-resolution subtraction MR-fistulography: comparison with surgical findings. J Magn Reson Imaging 19(1):91–98PubMedCrossRef
18.
go back to reference Horsthuis K, Lavini C, Bipat S (2009) Perianal Crohn disease: evaluation of dynamic contrast-enhanced MR imaging as an indicator of disease activity. Radiology 251(2):380–387PubMedCrossRef Horsthuis K, Lavini C, Bipat S (2009) Perianal Crohn disease: evaluation of dynamic contrast-enhanced MR imaging as an indicator of disease activity. Radiology 251(2):380–387PubMedCrossRef
19.
go back to reference deSouza NM, Gilderdale DJ, Coutts GA, Puni R, Steiner RE (1998) MRI of fistula-in-ano: a comparison of endoanal coil with external phased array coil techniques. J Comput Assist Tomogr 22(3):357–363PubMedCrossRef deSouza NM, Gilderdale DJ, Coutts GA, Puni R, Steiner RE (1998) MRI of fistula-in-ano: a comparison of endoanal coil with external phased array coil techniques. J Comput Assist Tomogr 22(3):357–363PubMedCrossRef
20.
go back to reference Halligan S, Bartram CI (1998) MR imaging of fistula in ano: are endoanal coils the gold standard? AJR Am J Roentgenol 171(2):407–412PubMedCrossRef Halligan S, Bartram CI (1998) MR imaging of fistula in ano: are endoanal coils the gold standard? AJR Am J Roentgenol 171(2):407–412PubMedCrossRef
21.
22.
go back to reference de Miguel Criado J, del Salto LG, Rivas PF, et al. (2012) MR imaging evaluation of perianal fistulas: spectrum of imaging features. Radiographics 32(1):175–194PubMedCrossRef de Miguel Criado J, del Salto LG, Rivas PF, et al. (2012) MR imaging evaluation of perianal fistulas: spectrum of imaging features. Radiographics 32(1):175–194PubMedCrossRef
23.
go back to reference Eisenhammer S (1958) A new approach to the anorectal fistulous abscess based on the high intermuscular lesion. Surg Gynecol Obstet 106(5):595–599PubMed Eisenhammer S (1958) A new approach to the anorectal fistulous abscess based on the high intermuscular lesion. Surg Gynecol Obstet 106(5):595–599PubMed
24.
go back to reference Parks AG, Gordon PH, Hardcastle JD (1976) A classification of fistula-in-ano. Br J Surg 63(1):1–12PubMedCrossRef Parks AG, Gordon PH, Hardcastle JD (1976) A classification of fistula-in-ano. Br J Surg 63(1):1–12PubMedCrossRef
25.
go back to reference de Miguel Criado J, Garcia del Salto L, Rivas PF, et al. (2012) MR imaging evaluation of perianal fistulas: spectrum of imaging features. Radiographics 32:175–194PubMedCrossRef de Miguel Criado J, Garcia del Salto L, Rivas PF, et al. (2012) MR imaging evaluation of perianal fistulas: spectrum of imaging features. Radiographics 32:175–194PubMedCrossRef
26.
go back to reference Spencer JA, Chapple K, Wilson D, et al. (1998) Outcome after surgery for perianal fistula: predictive value of MR imaging. AJR Am J Roentgenol 171(2):403–406PubMedCrossRef Spencer JA, Chapple K, Wilson D, et al. (1998) Outcome after surgery for perianal fistula: predictive value of MR imaging. AJR Am J Roentgenol 171(2):403–406PubMedCrossRef
27.
28.
29.
go back to reference Beets-Tan RG, Beets GL, van der Hoop AG, et al. (2001) Preoperative MR imaging of anal fistulas: does it really help the surgeon? Radiology 218(1):75–84PubMed Beets-Tan RG, Beets GL, van der Hoop AG, et al. (2001) Preoperative MR imaging of anal fistulas: does it really help the surgeon? Radiology 218(1):75–84PubMed
30.
go back to reference Buchanan GN, Halligan S, Bartram CI, et al. (2004) Clinical examination, endosonography, and MR imaging in preoperative assessment of fistula in ano: comparison with outcome-based reference standard. Radiology 233(3):674–681PubMedCrossRef Buchanan GN, Halligan S, Bartram CI, et al. (2004) Clinical examination, endosonography, and MR imaging in preoperative assessment of fistula in ano: comparison with outcome-based reference standard. Radiology 233(3):674–681PubMedCrossRef
31.
go back to reference van der Hagen SJ, Baeten CG, Soeters PB, et al. (2005) Anti-TNF-alpha (infliximab) used as induction treatment in case of active proctitis in a multistep strategy followed by definitive surgery of complex anal fistulas in Crohn’s disease: a preliminary report. Dis Colon Rectum 48(4):758–767PubMedCrossRef van der Hagen SJ, Baeten CG, Soeters PB, et al. (2005) Anti-TNF-alpha (infliximab) used as induction treatment in case of active proctitis in a multistep strategy followed by definitive surgery of complex anal fistulas in Crohn’s disease: a preliminary report. Dis Colon Rectum 48(4):758–767PubMedCrossRef
32.
go back to reference Buchanan G, Halligan S, Williams A, et al. (2002) Effect of MRI on clinical outcome of recurrent fistula-in-ano. Lancet 360(9346):1661–1662PubMedCrossRef Buchanan G, Halligan S, Williams A, et al. (2002) Effect of MRI on clinical outcome of recurrent fistula-in-ano. Lancet 360(9346):1661–1662PubMedCrossRef
33.
go back to reference Buchanan GN, Halligan S, Williams AB, et al. (2003) Magnetic resonance imaging for primary fistula in ano. Br J Surg 90(7):877–881PubMedCrossRef Buchanan GN, Halligan S, Williams AB, et al. (2003) Magnetic resonance imaging for primary fistula in ano. Br J Surg 90(7):877–881PubMedCrossRef
34.
go back to reference Buchanan GN, Halligan S, Taylor S, et al. (2004) MRI of fistula in ano: inter- and intraobserver agreement and effects of directed education. AJR Am J Roentgenol 183(1):135–140PubMedCrossRef Buchanan GN, Halligan S, Taylor S, et al. (2004) MRI of fistula in ano: inter- and intraobserver agreement and effects of directed education. AJR Am J Roentgenol 183(1):135–140PubMedCrossRef
35.
go back to reference Beckingham IJ, Spencer JA, Ward J, et al. (1996) Prospective evaluation of dynamic contrast enhanced magnetic resonance imaging in the evaluation of fistula in ano. Br J Surg 83(10):1396–1398PubMedCrossRef Beckingham IJ, Spencer JA, Ward J, et al. (1996) Prospective evaluation of dynamic contrast enhanced magnetic resonance imaging in the evaluation of fistula in ano. Br J Surg 83(10):1396–1398PubMedCrossRef
36.
go back to reference Williams JG, Farrands PA, Williams AB, et al. (2007) The treatment of anal fistula: ACPGBI position statement. Colorectal Dis 9(Suppl 4):18–50PubMedCrossRef Williams JG, Farrands PA, Williams AB, et al. (2007) The treatment of anal fistula: ACPGBI position statement. Colorectal Dis 9(Suppl 4):18–50PubMedCrossRef
37.
go back to reference Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB (2003) AGA technical review on perianal Crohn’s disease. Gastroenterology 125(5):1508–1530PubMedCrossRef Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB (2003) AGA technical review on perianal Crohn’s disease. Gastroenterology 125(5):1508–1530PubMedCrossRef
38.
go back to reference Keshaw H, Foong KS, Forbes A, et al. (2010) Perianal fistulae in Crohn’s Disease: current and future approaches to treatment. Inflamm Bowel Dis 16(5):870–880PubMedCrossRef Keshaw H, Foong KS, Forbes A, et al. (2010) Perianal fistulae in Crohn’s Disease: current and future approaches to treatment. Inflamm Bowel Dis 16(5):870–880PubMedCrossRef
Metadata
Title
MRI of perianal fistulas: bridging the radiological–surgical divide
Authors
Kenneth L. Gage
Swati Deshmukh
Katarzyna J. Macura
Ihab R. Kamel
Atif Zaheer
Publication date
01-10-2013
Publisher
Springer US
Published in
Abdominal Radiology / Issue 5/2013
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-012-9965-4

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